This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] See more...

Aliases for SLC27A6 Gene

Aliases for SLC27A6 Gene

  • Solute Carrier Family 27 Member 6 2 3 4 5
  • Fatty-Acid-Coenzyme A Ligase, Very Long-Chain 2 2 3 4
  • ACSVL2 2 3 4
  • FACVL2 2 3 4
  • FATP6 2 3 4
  • Solute Carrier Family 27 (Fatty Acid Transporter), Member 6 2 3
  • Very Long-Chain Acyl-CoA Synthetase Homolog 1 3 4
  • Long-Chain Fatty Acid Transport Protein 6 3 4
  • Arachidonate--CoA Ligase 3 4
  • VLCS-H1 2 3
  • Acyl-CoA Synthetase Very Long Chain Family, Member 2 3
  • Fatty Acid Transport Protein 6 4
  • EC 6.2.1.15 4
  • EC 6.2.1.7 50
  • EC 6.2.1.- 4
  • HVLCS-H1 4
  • EC 6.2.1 50
  • SLC27A6 5
  • FATP-6 4
  • VLCSH1 4

External Ids for SLC27A6 Gene

Previous GeneCards Identifiers for SLC27A6 Gene

  • GC00U990498
  • GC05P128212
  • GC05P128377
  • GC05P128328
  • GC05P127873
  • GC05P123491

Summaries for SLC27A6 Gene

Entrez Gene Summary for SLC27A6 Gene

  • This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for SLC27A6 Gene

SLC27A6 (Solute Carrier Family 27 Member 6) is a Protein Coding gene. Diseases associated with SLC27A6 include Platelet Glycoprotein Iv Deficiency and Restrictive Dermopathy, Lethal. Among its related pathways are Transport of vitamins, nucleosides, and related molecules and Insulin resistance. Gene Ontology (GO) annotations related to this gene include nucleotide binding and very long-chain fatty acid-CoA ligase activity. An important paralog of this gene is SLC27A2.

UniProtKB/Swiss-Prot Summary for SLC27A6 Gene

  • Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart (PubMed:12556534). Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs) (By similarity).

Gene Wiki entry for SLC27A6 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLC27A6 Gene

Genomics for SLC27A6 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SLC27A6 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05J128534 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 250.7 -1.0 -1012 5.6 ZNF600 ATF2 ZNF223 ZNF10 ZSCAN16 POLR2A ZIC2 ZBTB10 CEBPB FEZF1 FBN2 SLC27A6 lnc-C5orf63-6 CCDC192 HSALNG0044729 SLC12A2
GH05J128965 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas 269.9 +428.1 428088 3 ZNF600 ZIC2 HES1 ZNF341 KLF7 KLF9 SP2 PRDM10 ZBTB48 ZNF189 SLC27A6 RF00017-4396 piR-54324-018 ISOC1 FBN2
GH05J129093 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas 16 +557.9 557888 4.6 SP1 ZNF207 MYC ZNF600 IKZF1 SSRP1 ZNF580 KLF9 CEBPA ZNF223 ISOC1 HSALNG0044738 MIR4633 SLC27A6 ADAMTS19
GH05J129002 Enhancer 0.3 Ensembl 39.6 +464.7 464688 1.8 EGR1 SLC27A6 piR-38756-003 piR-56186-064 ISOC1 FBN2
GH05J129082 Enhancer 0.8 Ensembl 12.7 +544.8 544788 0.4 MYC NCOR1 ZNF592 BHLHE40 TAL1 RELA PRDM10 HLTF STAT5A MLLT1 lnc-ISOC1-2 SLC27A6 ISOC1 HSALNG0044735 LOC102723638 FBN2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLC27A6 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SLC27A6

Top Transcription factor binding sites by QIAGEN in the SLC27A6 gene promoter:
  • AML1a
  • COMP1
  • NF-1
  • NF-1/L

Genomic Locations for SLC27A6 Gene

Latest Assembly
chr5:128,538,013-129,033,642
(GRCh38/hg38)
Size:
495,630 bases
Orientation:
Plus strand

Previous Assembly
chr5:128,301,181-128,369,328
(GRCh37/hg19 by Entrez Gene)
Size:
68,148 bases
Orientation:
Plus strand

chr5:127,873,706-128,369,335
(GRCh37/hg19 by Ensembl)
Size:
495,630 bases
Orientation:
Plus strand

Genomic View for SLC27A6 Gene

Genes around SLC27A6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC27A6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC27A6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC27A6 Gene

Proteins for SLC27A6 Gene

  • Protein details for SLC27A6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y2P4-S27A6_HUMAN
    Recommended name:
    Long-chain fatty acid transport protein 6
    Protein Accession:
    Q9Y2P4
    Secondary Accessions:
    • Q6IAM5
    • Q7Z6E6
    • Q86YF6

    Protein attributes for SLC27A6 Gene

    Size:
    619 amino acids
    Molecular mass:
    70112 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC27A6 Gene

Selected DME Specific Peptides for SLC27A6 Gene

Q9Y2P4:
  • TSGTTGLPKA
  • QYIGELCRYL
  • RWKGENV

Post-translational modifications for SLC27A6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC27A6 Gene

Domains & Families for SLC27A6 Gene

Gene Families for SLC27A6 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters

Protein Domains for SLC27A6 Gene

InterPro:
Blocks:
  • AMP-binding signature

Suggested Antigen Peptide Sequences for SLC27A6 Gene

GenScript: Design optimal peptide antigens:
  • Very long-chain acyl-CoA synthetase homolog 1 (S27A6_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9Y2P4

UniProtKB/Swiss-Prot:

S27A6_HUMAN :
  • Belongs to the ATP-dependent AMP-binding enzyme family.
Family:
  • Belongs to the ATP-dependent AMP-binding enzyme family.
genes like me logo Genes that share domains with SLC27A6: view

Function for SLC27A6 Gene

Molecular function for SLC27A6 Gene

UniProtKB/Swiss-Prot Function:
Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart (PubMed:12556534). Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs) (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=hexadecanoate(out) = hexadecanoate(in); Xref=Rhea:RHEA:45256, ChEBI:CHEBI:7896; Evidence={ECO:0000269|PubMed:12556534};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=(9Z,12Z)-octadecadienoate(out) = (9Z,12Z)-octadecadienoate(in); Xref=Rhea:RHEA:45264, ChEBI:CHEBI:30245; Evidence={ECO:0000269|PubMed:12556534};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=(9Z)-octadecenoate(out) = (9Z)-octadecenoate(in); Xref=Rhea:RHEA:33655, ChEBI:CHEBI:30823; Evidence={ECO:0000269|PubMed:12556534};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=(5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate; Xref=Rhea:RHEA:19713, ChEBI:CHEBI:30616, ChEBI:CHEBI:32395, ChEBI:CHEBI:33019, ChEBI:CHEBI:57287, ChEBI:CHEBI:57368, ChEBI:CHEBI:456215; EC=6.2.1.15; Evidence={ECO:0000250|UniProtKB:E9Q9W4};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + CoA + tetracosanoate = AMP + diphosphate + tetracosanoyl-CoA; Xref=Rhea:RHEA:33639, ChEBI:CHEBI:30616, ChEBI:CHEBI:31014, ChEBI:CHEBI:33019, ChEBI:CHEBI:57287, ChEBI:CHEBI:65052, ChEBI:CHEBI:456215; Evidence={ECO:0000250|UniProtKB:E9Q9W4};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=(9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate; Xref=Rhea:RHEA:33607, ChEBI:CHEBI:30616, ChEBI:CHEBI:30823, ChEBI:CHEBI:33019, ChEBI:CHEBI:57287, ChEBI:CHEBI:57387, ChEBI:CHEBI:456215; Evidence={ECO:0000250|UniProtKB:E9Q9W4};.

Enzyme Numbers (IUBMB) for SLC27A6 Gene

Phenotypes From GWAS Catalog for SLC27A6 Gene

Gene Ontology (GO) - Molecular Function for SLC27A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003824 catalytic activity IEA --
GO:0004467 long-chain fatty acid-CoA ligase activity TAS,IBA 21873635
GO:0005324 long-chain fatty acid transporter activity IBA 21873635
GO:0016874 ligase activity IEA --
genes like me logo Genes that share ontologies with SLC27A6: view
genes like me logo Genes that share phenotypes with SLC27A6: view

Animal Models for research

  • Taconic Biosciences Mouse Models for SLC27A6

miRNA for SLC27A6 Gene

miRTarBase miRNAs that target SLC27A6

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC27A6

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC27A6 Gene

Localization for SLC27A6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC27A6 Gene

Cell membrane, sarcolemma. Multi-pass membrane protein. Cell membrane. Multi-pass membrane protein. Note=In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36. {ECO:0000305 PubMed:12556534}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SLC27A6 gene
Compartment Confidence
plasma membrane 5
peroxisome 3
extracellular 2
mitochondrion 2
nucleus 2
endoplasmic reticulum 2
cytosol 2
cytoskeleton 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SLC27A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0042383 sarcolemma IEA --
genes like me logo Genes that share ontologies with SLC27A6: view

Pathways & Interactions for SLC27A6 Gene

genes like me logo Genes that share pathways with SLC27A6: view

Gene Ontology (GO) - Biological Process for SLC27A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000038 very long-chain fatty acid metabolic process TAS 10471116
GO:0001676 long-chain fatty acid metabolic process IEA --
GO:0006629 lipid metabolic process IEA --
GO:0006631 fatty acid metabolic process IEA --
GO:0006869 lipid transport IEA --
genes like me logo Genes that share ontologies with SLC27A6: view

No data available for SIGNOR curated interactions for SLC27A6 Gene

Drugs & Compounds for SLC27A6 Gene

(5) Drugs for SLC27A6 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Palmitic Acid Approved Pharma 27
Stearic acid Approved, Experimental Pharma 0
arachidonic acid Experimental Pharma 41
Myristic acid Experimental Pharma 0
Tridecanoic acid Experimental Pharma 0

(7) Additional Compounds for SLC27A6 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Arachidic acid
  • Arachic acid
  • Arachidinic acid
  • Arachinsaeure
  • C20:0
  • CH3-[CH2]18-COOH
506-30-9
Heptadecanoic acid
  • 17:0
  • C17:0
  • CH3-[CH2]15-COOH
  • Heptadecoic acid
  • Heptadecylic acid
506-12-7
Heptadecanoyl CoA
  • Heptadecanoyl-coenzyme A
  • Heptadecanoate
  • Heptadecanoic acid
  • Heptadecanoic acid CoA
  • Heptadecanoyl coenzyme A
3546-17-6
Pentadecanoic acid
  • 15:00
  • C15
  • C15:0
  • N-Pentadecanoic acid
  • Pentadecylic acid
1002-84-2
genes like me logo Genes that share compounds with SLC27A6: view

Transcripts for SLC27A6 Gene

mRNA/cDNA for SLC27A6 Gene

3 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC27A6

Alternative Splicing Database (ASD) splice patterns (SP) for SLC27A6 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
SP1: -
SP2:
SP3: - -
SP4: -
SP5: -
SP6: - -

Relevant External Links for SLC27A6 Gene

GeneLoc Exon Structure for
SLC27A6

Expression for SLC27A6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SLC27A6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC27A6 Gene

This gene is overexpressed in Heart - Left Ventricle (x8.6), Esophagus - Muscularis (x5.7), Heart - Atrial Appendage (x5.2), and Adrenal Gland (x4.6).

Protein differential expression in normal tissues from HIPED for SLC27A6 Gene

This gene is overexpressed in Fetal heart (23.2), Retina (19.2), and Testis (7.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SLC27A6 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLC27A6

SOURCE GeneReport for Unigene cluster for SLC27A6 Gene:

Hs.49765

mRNA Expression by UniProt/SwissProt for SLC27A6 Gene:

Q9Y2P4-S27A6_HUMAN
Tissue specificity: Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus.

Evidence on tissue expression from TISSUES for SLC27A6 Gene

  • Liver(4.5)
  • Nervous system(4.5)
  • Heart(2.9)
  • Muscle(2.8)
  • Eye(2.1)
genes like me logo Genes that share expression patterns with SLC27A6: view

Primer products for research

No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC27A6 Gene

Orthologs for SLC27A6 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLC27A6 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SLC27A6 29 30
  • 99.25 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia SLC27A6 29 30
  • 87.02 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia SLC27A6 29 30
  • 83.98 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Slc27a6 29
  • 81.48 (n)
Mouse
(Mus musculus)
Mammalia Slc27a6 29 16 30
  • 80.29 (n)
OneToOne
Chicken
(Gallus gallus)
Aves SLC27A6 29 30
  • 72.11 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia SLC27A6 30
  • 66 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia slc27a6 29
  • 69.41 (n)
Str.16676 29
African clawed frog
(Xenopus laevis)
Amphibia Xl.9882 29
Zebrafish
(Danio rerio)
Actinopterygii LOC568883 29
  • 59.33 (n)
slc27a6 30
  • 55 (a)
OneToOne
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FAT1 30
  • 29 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 38 (a)
OneToMany
Species where no ortholog for SLC27A6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for SLC27A6 Gene

ENSEMBL:
Gene Tree for SLC27A6 (if available)
TreeFam:
Gene Tree for SLC27A6 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SLC27A6: view image
Alliance of Genome Resources:
Additional Orthologs for SLC27A6

Paralogs for SLC27A6 Gene

(6) SIMAP similar genes for SLC27A6 Gene using alignment to 2 proteins:

  • S27A6_HUMAN
  • D6RAJ2_HUMAN
genes like me logo Genes that share paralogs with SLC27A6: view

Variants for SLC27A6 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SLC27A6 Gene

SNP ID Clinical significance and condition Chr 05 pos Variation AA Info Type
rs2526247 -- p.Leu19Val

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SLC27A6 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SLC27A6 Gene

Variant ID Type Subtype PubMed ID
esv1008060 CNV deletion 20482838
esv1641373 CNV deletion 17803354
esv2407327 CNV deletion 18987734
esv2656691 CNV deletion 23128226
esv2730759 CNV deletion 23290073
esv2730760 CNV deletion 23290073
esv2730761 CNV deletion 23290073
esv2730763 CNV deletion 23290073
esv3324011 CNV insertion 20981092
esv3606738 CNV loss 21293372
esv3606739 CNV gain 21293372
esv3606741 CNV loss 21293372
esv3606743 CNV gain 21293372
esv5198 CNV loss 18987735
nsv1015525 CNV loss 25217958
nsv1074331 CNV deletion 25765185
nsv1121650 CNV deletion 24896259
nsv327282 CNV deletion 16902084
nsv328601 CNV insertion 16902084
nsv329438 CNV insertion 16902084
nsv329829 CNV deletion 16902084
nsv4996 CNV insertion 18451855
nsv599701 CNV gain 21841781
nsv819884 CNV gain 19587683
nsv830485 CNV gain 17160897
nsv958295 CNV deletion 24416366

Variation tolerance for SLC27A6 Gene

Residual Variation Intolerance Score: 83.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.65; 56.85% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SLC27A6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC27A6
Leiden Open Variation Database (LOVD)
SLC27A6

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC27A6 Gene

Disorders for SLC27A6 Gene

MalaCards: The human disease database

(5) MalaCards diseases for SLC27A6 Gene - From: COP and GCD

Disorder Aliases PubMed IDs
platelet glycoprotein iv deficiency
  • bleeding disorder, platelet-type, 10; bdplt10
restrictive dermopathy, lethal
  • tight skin contracture syndrome, lethal
melkersson-rosenthal syndrome
  • mros; mrs
persistent fetal circulation syndrome
  • congenital alveolar capillary dysplasia with misalignment of pulmonary veins
dilated cardiomyopathy
  • congestive cardiomyopathy
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SLC27A6

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with SLC27A6: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SLC27A6 Gene

Publications for SLC27A6 Gene

  1. Characterization of a heart-specific fatty acid transport protein. (PMID: 12556534) Gimeno RE … Stahl A (The Journal of biological chemistry 2003) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein. (PMID: 10479480) Steinberg SJ … Watkins PA (Molecular genetics and metabolism 1999) 2 3
  4. New Insight on Solute Carrier Family 27 Member 6 (SLC27A6) in Tumoral and Non-Tumoral Breast Cells. (PMID: 30911270) Yen MC … Hsu YL (International journal of medical sciences 2019) 3
  5. Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. (PMID: 30021884) Fasci D … Heck AJR (Molecular & cellular proteomics : MCP 2018) 3

Products for SLC27A6 Gene

Sources for SLC27A6 Gene