Aliases for SLC26A11 Gene
External Ids for SLC26A11 Gene
Previous GeneCards Identifiers for SLC26A11 Gene
This gene encodes a member of the solute linked carrier 26 family of anion exchangers. Members of this family of proteins are essential for numerous cellular functions including homeostasis and intracellular electrolyte balance. The encoded protein is a sodium independent sulfate transporter that is sensitive to the anion exchanger inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
GeneCards Summary for SLC26A11 Gene
SLC26A11 (Solute Carrier Family 26 Member 11) is a Protein Coding gene. Diseases associated with SLC26A11 include Deafness, Autosomal Dominant 20. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include secondary active sulfate transmembrane transporter activity and sulfate transmembrane transporter activity.
UniProtKB/Swiss-Prot for SLC26A11 Gene
Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC).