Aliases for SLC25A6 Gene
External Ids for SLC25A6 Gene
Previous HGNC Symbols for SLC25A6 Gene
Previous GeneCards Identifiers for SLC25A6 Gene
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]
GeneCards Summary for SLC25A6 Gene
SLC25A6 (Solute Carrier Family 25 Member 6) is a Protein Coding gene. Diseases associated with SLC25A6 include Influenza and Bubonic Plague. Among its related pathways are Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins and HIV Life Cycle. Gene Ontology (GO) annotations related to this gene include transporter activity and ATP:ADP antiporter activity. An important paralog of this gene is SLC25A5.
UniProtKB/Swiss-Prot Summary for SLC25A6 Gene
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.