Aliases for SLC25A6 Gene
Aliases for SLC25A6 Gene
External Ids for SLC25A6 Gene
Previous HGNC Symbols for SLC25A6 Gene
- ANT3
Previous GeneCards Identifiers for SLC25A6 Gene
- GC0XM000980
- GC0XM000821
- GC0XM001081
- GC0XM001150
- GC0YM001548
- GC0XM001548
- GC0XM001465
- GC0XM001505
Summaries for SLC25A6 Gene
-
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]
GeneCards Summary for SLC25A6 Gene
SLC25A6 (Solute Carrier Family 25 Member 6) is a Protein Coding gene. Diseases associated with SLC25A6 include Male Reproductive Organ Benign Neoplasm and Autosomal Dominant Progressive External Ophthalmoplegia. Among its related pathways are Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins and Transport of the SLBP independent Mature mRNA. Gene Ontology (GO) annotations related to this gene include transporter activity and ATP:ADP antiporter activity. An important paralog of this gene is SLC25A5.
UniProtKB/Swiss-Prot for SLC25A6 Gene
-
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Additional gene information for SLC25A6 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC25A6 Gene
Genomics for SLC25A6 Gene
GeneHancer (GH) Regulatory Elements for SLC25A6 Gene
Promoters and enhancers for SLC25A6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around SLC25A6 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the SLC25A6 gene promoter:
-
- Pax-5
- PPAR-gamma2
- PPAR-gamma1
- GCNF
- GCNF-1
Regulatory Element Products
Genomic Locations for SLC25A6 Gene
Genomic Locations for SLC25A6 Gene
- chrX:1,386,152-1,392,724
- (GRCh38/hg38)
- Size:
- 6,573 bases
- Orientation:
- Minus strand
- chrX:1,505,045-1,511,617
- (GRCh37/hg19)
- Size:
- 6,573 bases
- Orientation:
- Minus strand
Genomic View for SLC25A6 Gene
Genes around SLC25A6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp22.33 and Yp11.2 by Entrez Gene
- Xp22.32 and Yp11.3 by HGNC
- Xp22.33 by Ensembl
SLC25A6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SLC25A6 Gene
Proteins for SLC25A6 Gene
-
Protein details for SLC25A6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P12236-ADT3_HUMAN
- Recommended name:
- ADP/ATP translocase 3
- Protein Accession:
- P12236
- Q96C49
Protein attributes for SLC25A6 Gene
- Size:
- 298 amino acids
- Molecular mass:
- 32866 Da
- Quaternary structure:
-
- Found in a complex with ARL2, ARL2BP and SLC25A6 (By similarity). Homodimer. Interacts with influenza A virus PB1-F2 protein and HIV-1 Vpr.
- Miscellaneous:
-
- The gene coding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.
Protein Expression for SLC25A6 Gene
Post-translational modifications for SLC25A6 Gene
Other Protein References for SLC25A6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for SLC25A6
- Invitrogen Antibodies for SLC25A6
- GeneTex SLC25A6 Antibody for SLC25A6
-
Santa Cruz Biotechnology (SCBT) Antibodies for SLC25A6
Protein Products
-
OriGene Purified Proteins for SLC25A6
- Search Origene for MassSpec and Protein Over-expression Lysates for SLC25A6
- Origene Custom Protein Services for SLC25A6
- antibodies-online: Search results for 5 available SLC25A6 Proteins ranked by validation data
- Compare Top SLC25A6 Proteins
-
Quality Products:
- Search GeneTex for Proteins for SLC25A6
Assay Products
- antibodies-online: Search results for 7 available SLC25A6 Elisa Kits ranked by validation data
- Compare Top SLC25A6 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SLC25A6 Gene
Domains & Families for SLC25A6 Gene
Gene Families for SLC25A6 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- FDA approved drug targets
- Plasma proteins
- Predicted membrane proteins
- Transporters
Protein Domains for SLC25A6 Gene
Suggested Antigen Peptide Sequences for SLC25A6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P12236UniProtKB/Swiss-Prot:
ADT3_HUMAN :- The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.
- Belongs to the mitochondrial carrier (TC 2.A.29) family.
- Domain:
-
- The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.
- Family:
-
- Belongs to the mitochondrial carrier (TC 2.A.29) family.
Function for SLC25A6 Gene
Molecular function for SLC25A6 Gene
- UniProtKB/Swiss-Prot Function:
- Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005471 | ATP:ADP antiporter activity | NAS | 2541251 |
| GO:0005515 | protein binding | IPI | 21370995 |
| GO:0015207 | adenine transmembrane transporter activity | TAS | -- |
| GO:0022857 | transmembrane transporter activity | IBA,IEA | -- |
Phenotypes for SLC25A6 Gene
- GenomeRNAi human phenotypes for SLC25A6:
-
- Decreased homologous recombination repair frequency
- Negative genetic interaction between BLM-/- and BLM+/+
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- shRNA abundance <= 50%
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SLC25A6
-
CRISPR Products
-
OriGene CRISPR knockouts for SLC25A6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SLC25A6
- genomics-online: gRNA clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
- Applied Biological Materials CRISPR for SLC25A6
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA for SLC25A6 Gene
- miRTarBase miRNAs that target SLC25A6
-
- hsa-mir-16-5p (MIRT031609)
- hsa-mir-421 (MIRT039389)
- hsa-mir-423-3p (MIRT042493)
- hsa-mir-204-3p (MIRT738832)
- hsa-mir-3148 (MIRT740246)
- hsa-mir-3153 (MIRT740399)
- hsa-mir-4438 (MIRT744505)
- hsa-mir-4505 (MIRT745541)
- hsa-mir-4514 (MIRT745726)
- hsa-mir-4646-5p (MIRT746442)
- hsa-mir-4668-5p (MIRT746830)
- hsa-mir-4692 (MIRT747132)
- hsa-mir-5095 (MIRT749699)
- hsa-mir-549a (MIRT750845)
- hsa-mir-5787 (MIRT751490)
- hsa-mir-6733-5p (MIRT754123)
- hsa-mir-6739-5p (MIRT754320)
- hsa-mir-6808-5p (MIRT756601)
- hsa-mir-6893-5p (MIRT758746)
- hsa-mir-7151-3p (MIRT759182)
- hsa-mir-940 (MIRT760842)
- hsa-mir-139-5p (MIRT762612)
miRNA Products
Inhibitory RNA Products
- Origene shrna and RNAi products in human, mouse, rat for SLC25A6
- Browse OriGene Inhibitory RNA Products For SLC25A6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC25A6
- genomics-online: shRNA clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
Clone Products
- Sino Biological Human cDNA Clone for SLC25A6
- VectorBuilder custom plasmid, inducible vectors for SLC25A6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SLC25A6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SLC25A6
- Applied Biological Materials Clones for SLC25A6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for SLC25A6
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC25A6 Gene
Localization for SLC25A6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SLC25A6 Gene
- Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| mitochondrion | 5 |
| nucleus | 5 |
| cytosol | 2 |
| peroxisome | 1 |
- Mitochondria (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | HDA | 21630459 |
| GO:0005739 | mitochondrion | IEA,IDA | -- |
| GO:0005743 | mitochondrial inner membrane | TAS | -- |
| GO:0005744 | mitochondrial inner membrane presequence translocase complex | TAS | 2541251 |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for SLC25A6 Gene
Pathways by source for SLC25A6 Gene
1 BioSystems pathway for SLC25A6 Gene
14 Reactome pathways for SLC25A6 Gene
8 KEGG pathways for SLC25A6 Gene
1 GeneGo (Thomson Reuters) pathway for SLC25A6 Gene
2 Qiagen pathways for SLC25A6 Gene
Interacting Proteins for SLC25A6 Gene
Selected Interacting proteins:
P12236-ADT3_HUMAN
ENSP00000370808
for SLC25A6 Gene via
IID
UniProtKB
MINT
STRING
GPS-Prot Interaction Network for SLC25A6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006626 | protein targeting to mitochondrion | TAS | -- |
| GO:0006839 | mitochondrial transport | IBA | -- |
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0015853 | adenine transport | IEA | -- |
| GO:0015866 | ADP transport | IEA | -- |
No data available for SIGNOR curated interactions for SLC25A6 Gene
Drugs & Compounds for SLC25A6 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
(1) ApexBio Compounds for SLC25A6 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Atractyloside Dipotassium Salt | ANT inhibitor | 102130-43-8 |
Transcripts for SLC25A6 Gene
mRNA/cDNA for SLC25A6 Gene
- (1) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (2534) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000381401 2062 bps (uc004cpt.4 uc004fpg.4)
- ENST00000475167 900 bps (uc064xtn.1 uc065cnp.1)
- ENST00000484026 854 bps (uc064xto.1 uc065cnq.1)
Unigene Clusters for SLC25A6 Gene
- Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for SLC25A6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SLC25A6
- genomics-online: gRNA clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
- Applied Biological Materials CRISPR for SLC25A6
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
Inhibitory RNA Products
- Origene shrna and RNAi products in human, mouse, rat for SLC25A6
- Browse OriGene Inhibitory RNA Products For SLC25A6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC25A6
- genomics-online: shRNA clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
Clone Products
- Sino Biological Human cDNA Clone for SLC25A6
- VectorBuilder custom plasmid, inducible vectors for SLC25A6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SLC25A6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SLC25A6
- Applied Biological Materials Clones for SLC25A6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | · | 4f | ^ | 5a | · | 5b | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||
| SP8: | - | - | - | ||||||||||||||||||||||||||||||
| SP9: |
Expression for SLC25A6 Gene
This gene is overexpressed in Nasal epithelium (13.2), Brain (7.6), and Frontal cortex (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SLC25A6 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SLC25A6 Gene:
SLC25A6SOURCE GeneReport for Unigene cluster for SLC25A6 Gene:
Hs.350927Evidence on tissue expression from TISSUES for SLC25A6 Gene
- Lung(5)
- Nervous system(5)
- Eye(4.9)
- Liver(4.9)
- Intestine(4.4)
- Muscle(4.3)
- Skin(4.3)
- Pancreas(4)
- Stomach(4)
- Kidney(3.7)
- Blood(3.6)
- Heart(3.2)
- Spleen(2.2)
- Thyroid gland(2.2)
- Adrenal gland(2)
- Bone(2)
- Bone marrow(2)
- Lymph node(2)
Primer Products
-
OriGene qPCR primer pairs and template standards for SLC25A6
-
OriGene qPCR primer pairs for SLC25A6
- genomics-online: primer clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC25A6 Gene
Orthologs for SLC25A6 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| cow (Bos Taurus) |
Mammalia | SLC25A6 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SLC25A6 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Slc25a6 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | SLC25A6 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | -- 34 |
|
ManyToMany | |
| SLC25A6 33 |
|
||||
| lizard (Anolis carolinensis) |
Reptilia | SLC25A6 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | slc25a6 34 33 |
|
ManyToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | sesB 34 35 |
|
ManyToMany | |
| Ant2 34 35 33 |
|
ManyToMany | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | ADT1_ANOGA 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | K01H12.2 35 |
|
|
|
| T01B11.4 35 |
|
|
|||
| ant-1.3 33 |
|
||||
| W02D3.6 35 |
|
|
|||
| ant-1.2 34 |
|
ManyToMany | |||
| C47E12.2 35 |
|
|
|||
| F25B4.7 35 |
|
|
|||
| R07E3.4 35 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | AAC3 34 |
|
ManyToMany | |
| AAC1 34 |
|
ManyToMany | |||
| PET9 34 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2354 34 |
|
ManyToMany |
- Species where no ortholog for SLC25A6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Evolution for SLC25A6 Gene
- ENSEMBL:
- Gene Tree for SLC25A6 (if available)
- TreeFam:
- Gene Tree for SLC25A6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SLC25A6: view image
Paralogs for SLC25A6 Gene
(8) SIMAP similar genes for SLC25A6 Gene using alignment to 3 proteins:
- ADT3_HUMAN
- I7HJJ0_HUMAN
- Q6I9V5_HUMAN
Pseudogenes.org Pseudogenes for SLC25A6 Gene
Variants for SLC25A6 Gene
| SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1055341021 | -- | 1,386,652(-) | C/A | coding_sequence_variant, missense_variant | |
| rs111324409 | -- | 1,391,690(-) | G/A | intron_variant | |
| rs111338474 | -- | 1,388,330(-) | G/C | intron_variant | |
| rs11211819 | -- | 1,386,577(-) | G/A/T | 3_prime_UTR_variant | |
| rs112264344 | -- | 1,390,908(-) | G/A/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1115920 | CNV | duplication | 24896259 |
| esv29996 | CNV | loss | 17803354 |
| esv2666429 | CNV | deletion | 23128226 |
| esv21933 | CNV | gain+loss | 19812545 |
| dgv1299e201 | CNV | deletion | 23290073 |
Residual Variation Intolerance Score:
2.37% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.01;
60.28% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SLC25A6 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC25A6 Gene
Disorders for SLC25A6 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| male reproductive organ benign neoplasm |
|
|
| autosomal dominant progressive external ophthalmoplegia |
|
|
| influenza |
|
|
Search SLC25A6 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SLC25A6
No data available for UniProtKB/Swiss-Prot and Genatlas for SLC25A6 Gene
Publications for SLC25A6 Gene
- Molecular interactions between mitochondrial membrane proteins and the C-terminal domain of PB1-F2: an in silico approach. (PMID: 19669810) Danishuddin M … Khan AU (Journal of molecular modeling 2010) 3 22 58
- Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells. (PMID: 17855512) Yang Z … Gu J (Molecular biology of the cell 2007) 3 22 58
- IL-4-induced upregulation of adenine nucleotide translocase 3 and its role in Th cell survival from apoptosis. (PMID: 16930576) Jang JY … Lee CE (Cellular immunology 2006) 3 22 58
- Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. (PMID: 16201016) Zamarin D … Palese P (PLoS pathogens 2005) 3 4 58
- Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells. (PMID: 15063741) Zamora M … Viñas O (FEBS letters 2004) 3 22 58
Products for SLC25A6 Gene
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- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for SLC25A6
- Sino Biological Human cDNA Clone for SLC25A6
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SLC25A6
- Novus Biologicals lysates and proteins for SLC25A6
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for SLC25A6
- ApexBio compounds for SLC25A6
- Cyagen custom Knockout/knockin (KOKI) mouse models for SLC25A6
- VectorBuilder custom plasmid, inducible vectors for SLC25A6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SLC25A6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 61 available SLC25A6 Antibodies ranked by validation data
- Compare Top SLC25A6 Antibodies
- antibodies-online: Search results for 7 available SLC25A6 Elisa Kits ranked by validation data
- Compare Top SLC25A6 Elisa Kits
- Quality Products:
- antibodies-online: Search results for 5 available SLC25A6 Proteins ranked by validation data
- Compare Top SLC25A6 Proteins
- Quality Products:
- GeneTex SLC25A6 Antibody for SLC25A6
- Search GeneTex for Proteins for SLC25A6
- Santa Cruz Biotechnology (SCBT) Antibodies for SLC25A6
- Search Santa Cruz Biotechnology (SCBT) for SLC25A6 siRNA/shRNA
- Browse Santa Cruz Biotechnology (SCBT) for SLC25A6 CRISPR
- Horizon Cell Lines for SLC25A6
- genomics-online: cdna clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
- orf clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
- genomics-online: gRNA clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
- genomics-online: primer clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
- genomics-online: shRNA clones - Search results for 98 available SLC25A6 gene related products
- Overview of 98 available SLC25A6 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SLC25A6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SLC25A6
- GeneCopoeia miRNA 3'UTR Target clone products for SLC25A6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC25A6
Sources for SLC25A6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt