Aliases for SLC25A25 Gene
- Solute Carrier Family 25 Member 25 2 3 4 5
- Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 25 2 3
- Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 3 3 4
- Calcium-Binding Mitochondrial Carrier Protein SCaMC-2 3 4
- Mitochondrial ATP-Mg/Pi Carrier Protein 3 3 4
- KIAA1896 2 4
- PCSCL 2 3
- MCSC 2 3
External Ids for SLC25A25 Gene
Previous GeneCards Identifiers for SLC25A25 Gene
The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012]
GeneCards Summary for SLC25A25 Gene
SLC25A25 (Solute Carrier Family 25 Member 25) is a Protein Coding gene. Diseases associated with SLC25A25 include Nephrolithiasis and Nephrolithiasis, Calcium Oxalate. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is SLC25A23.
UniProtKB/Swiss-Prot Summary for SLC25A25 Gene
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.