This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] See more...

Aliases for SLC25A24 Gene

Aliases for SLC25A24 Gene

  • Solute Carrier Family 25 Member 24 2 3 4 5
  • APC1 2 3 4
  • Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 24 2 3
  • Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 1 3 4
  • Calcium-Binding Mitochondrial Carrier Protein SCaMC-1 3 4
  • Small Calcium-Binding Mitochondrial Carrier Protein 1 3 4
  • Mitochondrial ATP-Mg/Pi Carrier Protein 1 3 4
  • SCAMC1 3 4
  • Short Calcium-Binding Mitochondrial Carrier 1 3
  • Calcium-Binding Transporter 3
  • DKFZp586G0123 2
  • SLC25A24 5
  • SCAMC-1 3
  • MCSC1 4

External Ids for SLC25A24 Gene

Previous GeneCards Identifiers for SLC25A24 Gene

  • GC01M108033
  • GC01M108389
  • GC01M108677
  • GC01M106625

Summaries for SLC25A24 Gene

Entrez Gene Summary for SLC25A24 Gene

  • This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

GeneCards Summary for SLC25A24 Gene

SLC25A24 (Solute Carrier Family 25 Member 24) is a Protein Coding gene. Diseases associated with SLC25A24 include Fontaine Progeroid Syndrome and Progeroid Syndrome. Gene Ontology (GO) annotations related to this gene include calcium ion binding and ATP transmembrane transporter activity. An important paralog of this gene is SLC25A25.

UniProtKB/Swiss-Prot Summary for SLC25A24 Gene

  • Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is activated by an increase in cytosolic calcium levels. May play a role in protecting cells against oxidative stress-induced cell death, probably by promoting the formation of calcium-phosphate precipitates in the mitochondrial matrix, and thereby buffering calcium levels in the mitochondrial matrix.

Additional gene information for SLC25A24 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLC25A24 Gene

Genomics for SLC25A24 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SLC25A24 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLC25A24 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SLC25A24

Top Transcription factor binding sites by QIAGEN in the SLC25A24 gene promoter:
  • FOXL1
  • Oct-B1
  • oct-B2
  • oct-B3
  • POU2F1
  • POU2F1a
  • POU2F2
  • POU2F2 (Oct-2.1)
  • POU2F2B
  • POU2F2C

Genomic Locations for SLC25A24 Gene

Genomic Locations for SLC25A24 Gene
chr1:108,134,043-108,200,849
(GRCh38/hg38)
Size:
66,807 bases
Orientation:
Minus strand
chr1:108,676,658-108,743,471
(GRCh37/hg19)
Size:
66,814 bases
Orientation:
Minus strand

Genomic View for SLC25A24 Gene

Genes around SLC25A24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC25A24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC25A24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC25A24 Gene

Proteins for SLC25A24 Gene

  • Protein details for SLC25A24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NUK1-SCMC1_HUMAN
    Recommended name:
    Calcium-binding mitochondrial carrier protein SCaMC-1
    Protein Accession:
    Q6NUK1
    Secondary Accessions:
    • B7ZAI9
    • Q5T331
    • Q5T485
    • Q6PJJ9
    • Q705K4
    • Q9P129

    Protein attributes for SLC25A24 Gene

    Size:
    477 amino acids
    Molecular mass:
    53354 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF28888.1; Type=Frameshift; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for SLC25A24 Gene

    Alternative splice isoforms for SLC25A24 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC25A24 Gene

Post-translational modifications for SLC25A24 Gene

  • Ubiquitination at Lys62
  • Modification sites at PhosphoSitePlus

Other Protein References for SLC25A24 Gene

No data available for DME Specific Peptides for SLC25A24 Gene

Domains & Families for SLC25A24 Gene

Gene Families for SLC25A24 Gene

Protein Domains for SLC25A24 Gene

InterPro:
Blocks:
  • Mitochondrial carrier protein signature
ProtoNet:

Suggested Antigen Peptide Sequences for SLC25A24 Gene

GenScript: Design optimal peptide antigens:
  • Solute carrier family 25 member 24 (SCMC1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6NUK1

UniProtKB/Swiss-Prot:

SCMC1_HUMAN :
  • The N-terminal domain can bind calcium and regulates the ATP carrier activity of the transmembrane domain. The apo form of the N-terminal domain is intrinsically disordered and binds to the transmembrane domain, leading to inhibition of the ATP carrier activity. Calcium binding leads to a major conformation change and abolishes the interaction with the transmembrane domain and the inhibition of the ATP carrier activity (PubMed:24332718).
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
Domain:
  • The N-terminal domain can bind calcium and regulates the ATP carrier activity of the transmembrane domain. The apo form of the N-terminal domain is intrinsically disordered and binds to the transmembrane domain, leading to inhibition of the ATP carrier activity. Calcium binding leads to a major conformation change and abolishes the interaction with the transmembrane domain and the inhibition of the ATP carrier activity (PubMed:24332718).
Family:
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
genes like me logo Genes that share domains with SLC25A24: view

Function for SLC25A24 Gene

Molecular function for SLC25A24 Gene

UniProtKB/Swiss-Prot Function:
Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is activated by an increase in cytosolic calcium levels. May play a role in protecting cells against oxidative stress-induced cell death, probably by promoting the formation of calcium-phosphate precipitates in the mitochondrial matrix, and thereby buffering calcium levels in the mitochondrial matrix.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.97 mM for AMP {ECO:0000269|PubMed:15123600}; KM=0.3 mM for ADP {ECO:0000269|PubMed:15123600}; KM=0.33 mM for ATP {ECO:0000269|PubMed:15123600}; KM=0.2 mM for ATP-Mg {ECO:0000269|PubMed:15123600}; KM=1.64 mM for Pi {ECO:0000269|PubMed:15123600}; Vmax=337 umol/min/g enzyme with AMP as substrate {ECO:0000269|PubMed:15123600}; Vmax=345 umol/min/g enzyme with ADP as substrate {ECO:0000269|PubMed:15123600}; Vmax=320 umol/min/g enzyme with ATP as substrate {ECO:0000269|PubMed:15123600}; Vmax=365 umol/min/g enzyme with ATP-Mg as substrate {ECO:0000269|PubMed:15123600}; Vmax=380 umol/min/g enzyme with Pi as substrate {ECO:0000269|PubMed:15123600};

Phenotypes From GWAS Catalog for SLC25A24 Gene

Gene Ontology (GO) - Molecular Function for SLC25A24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005347 ATP transmembrane transporter activity IMP 22015608
GO:0005509 calcium ion binding IEA,IDA 24332718
GO:0022857 transmembrane transporter activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with SLC25A24: view
genes like me logo Genes that share phenotypes with SLC25A24: view

Human Phenotype Ontology for SLC25A24 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SLC25A24 Gene

MGI Knock Outs for SLC25A24:

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC25A24

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC25A24

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for SLC25A24 Gene

Localization for SLC25A24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC25A24 Gene

Mitochondrion inner membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SLC25A24 gene
Compartment Confidence
mitochondrion 5
cytosol 3
plasma membrane 2
peroxisome 2
nucleus 2
extracellular 1
cytoskeleton 1
endoplasmic reticulum 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for SLC25A24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA 22015608
GO:0005743 mitochondrial inner membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA,IDA 24332718
genes like me logo Genes that share ontologies with SLC25A24: view

Pathways & Interactions for SLC25A24 Gene

PathCards logo

SuperPathways for SLC25A24 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SLC25A24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006839 mitochondrial transport IMP 22015608
GO:0010941 regulation of cell death IMP 22015608
GO:0015867 ATP transport IMP 22015608
GO:0034599 cellular response to oxidative stress IMP 22015608
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC25A24: view

No data available for Pathways by source and SIGNOR curated interactions for SLC25A24 Gene

Drugs & Compounds for SLC25A24 Gene

(1) Drugs for SLC25A24 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Calcium Nutra 6556
genes like me logo Genes that share compounds with SLC25A24: view

Transcripts for SLC25A24 Gene

mRNA/cDNA for SLC25A24 Gene

2 REFSEQ mRNAs :
19 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC25A24

Alternative Splicing Database (ASD) splice patterns (SP) for SLC25A24 Gene

No ASD Table

Relevant External Links for SLC25A24 Gene

GeneLoc Exon Structure for
SLC25A24

Expression for SLC25A24 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SLC25A24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SLC25A24 Gene

This gene is overexpressed in Nasal epithelium (31.4) and Bone (15.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SLC25A24 Gene



Protein tissue co-expression partners for SLC25A24 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLC25A24

SOURCE GeneReport for Unigene cluster for SLC25A24 Gene:

Hs.656870

mRNA Expression by UniProt/SwissProt for SLC25A24 Gene:

Q6NUK1-SCMC1_HUMAN
Tissue specificity: Present in various cell lines (at protein level). Expressed in all tissues tested. Highly expressed in testis, expressed at intermediate level in small intestine and pancreas, and weakly expressed in kidney, spleen, liver, skeletal muscle and heart.

Evidence on tissue expression from TISSUES for SLC25A24 Gene

  • Nervous system(4.4)
  • Eye(4.2)
genes like me logo Genes that share expression patterns with SLC25A24: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC25A24 Gene

Orthologs for SLC25A24 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC25A24 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SLC25A24 30 31
  • 99.72 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia SLC25A24 31
  • 95 (a)
OneToOne
LOC534742 30
  • 91.68 (n)
Dog
(Canis familiaris)
Mammalia SLC25A24 30 31
  • 91.35 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Slc25a24 30 17 31
  • 87.37 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Slc25a24 30
  • 86.88 (n)
Oppossum
(Monodelphis domestica)
Mammalia SLC25A24 31
  • 80 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia SLC25A24 31
  • 71 (a)
OneToOne
Chicken
(Gallus gallus)
Aves SLC25A24 30 31
  • 77.46 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 78 (a)
OneToMany
-- 31
  • 65 (a)
OneToMany
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia slc25a24 30
  • 70.68 (n)
African clawed frog
(Xenopus laevis)
Amphibia LOC398474 30
Zebrafish
(Danio rerio)
Actinopterygii zgc:92470 30
  • 65.41 (n)
SLC25A24 31
  • 65 (a)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta CG32103 31
  • 41 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea F17E5.2 31
  • 40 (a)
ManyToMany
F55A11.4 31
  • 39 (a)
ManyToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SAL1 33
Thale Cress
(Arabidopsis thaliana)
eudicotyledons AT5G51050 30
  • 49.96 (n)
Rice
(Oryza sativa)
Liliopsida Os.26881 30
Fission Yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBC12D12.05c 30
  • 50.46 (n)
Bread mold
(Neurospora crassa)
Ascomycetes NCU01564 30
  • 47.03 (n)
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.5381 31
  • 43 (a)
OneToMany
Species where no ortholog for SLC25A24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for SLC25A24 Gene

ENSEMBL:
Gene Tree for SLC25A24 (if available)
TreeFam:
Gene Tree for SLC25A24 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SLC25A24: view image

Paralogs for SLC25A24 Gene

(15) SIMAP similar genes for SLC25A24 Gene using alignment to 3 proteins:

  • SCMC1_HUMAN
  • H3BMI3_HUMAN
  • J3KN42_HUMAN

Pseudogenes.org Pseudogenes for SLC25A24 Gene

genes like me logo Genes that share paralogs with SLC25A24: view

Variants for SLC25A24 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SLC25A24 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
692155 Likely Pathogenic: Dementia; Generalized tonic-clonic seizures 108,155,047(-) C/G MISSENSE_VARIANT
692156 Uncertain Significance: Dementia; Generalized tonic-clonic seizures 108,136,814(-) G/T MISSENSE_VARIANT
712421 Likely Benign: not provided 108,148,284(-) T/C MISSENSE_VARIANT
754041 Likely Benign: not provided 108,139,202(-) T/TC FRAMESHIFT_VARIANT
786852 Benign: not provided 108,185,940(-) A/T SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for SLC25A24 Gene

Structural Variations from Database of Genomic Variants (DGV) for SLC25A24 Gene

Variant ID Type Subtype PubMed ID
dgv248n100 CNV gain 25217958
dgv469n54 CNV gain 21841781
dgv475n54 CNV loss 21841781
dgv476n54 CNV loss 21841781
dgv477n54 CNV loss 21841781
dgv478n54 CNV loss 21841781
dgv479n54 CNV loss 21841781
dgv480n54 CNV loss 21841781
dgv481n54 CNV loss 21841781
dgv482n54 CNV loss 21841781
dgv59e199 CNV deletion 23128226
dgv5e180 CNV gain 20482838
dgv62n67 CNV loss 20364138
dgv73e212 CNV loss 25503493
esv2122744 CNV deletion 18987734
esv21858 CNV gain+loss 19812545
esv22495 CNV loss 19812545
esv2421780 CNV deletion 20811451
esv2498743 CNV loss 19546169
esv2623047 CNV deletion 19546169
esv2665550 CNV deletion 23128226
esv2675031 CNV deletion 23128226
esv2715906 CNV deletion 23290073
esv2758958 CNV gain+loss 17122850
esv2763802 CNV loss 21179565
esv32547 CNV gain 17666407
esv32800 CNV loss 17666407
esv33273 CNV gain 17666407
esv3567170 CNV deletion 23714750
esv3578060 CNV loss 25503493
esv3578065 CNV loss 25503493
esv3578068 CNV loss 25503493
esv3578071 CNV loss 25503493
esv3587125 CNV loss 21293372
esv3587126 CNV gain 21293372
esv3739 CNV loss 18987735
esv9427 CNV loss 19470904
nsv1004890 CNV loss 25217958
nsv1007150 CNV gain 25217958
nsv1011093 CNV gain 25217958
nsv10539 CNV gain+loss 18304495
nsv1161256 CNV deletion 26073780
nsv2265 CNV deletion 18451855
nsv428179 CNV gain 18775914
nsv433387 CNV loss 18776910
nsv442958 CNV loss 18776908
nsv498678 CNV loss 21111241
nsv508459 CNV deletion 20534489
nsv513999 CNV loss 21397061
nsv517978 CNV loss 19592680
nsv524680 CNV gain 19592680
nsv526757 CNV loss 19592680
nsv547358 CNV gain 21841781
nsv547393 CNV gain 21841781
nsv547396 CNV loss 21841781
nsv819227 CNV gain 19587683
nsv820521 CNV deletion 20802225
nsv823842 CNV gain 20364138
nsv823853 CNV loss 20364138
nsv947441 CNV deletion 23825009

Variation tolerance for SLC25A24 Gene

Residual Variation Intolerance Score: 44.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.17; 23.61% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SLC25A24 Gene

Human Gene Mutation Database (HGMD)
SLC25A24
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC25A24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC25A24 Gene

Disorders for SLC25A24 Gene

MalaCards: The human disease database

(9) MalaCards diseases for SLC25A24 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
fontaine progeroid syndrome
  • fps
progeroid syndrome
  • syndrome, progeroid
sengers syndrome
  • mitochondrial dna depletion syndrome 10 ; mtdps10
craniosynostosis
  • craniostenosis
hypertrichosis
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

SCMC1_HUMAN
  • Fontaine progeroid syndrome (FPS) [MIM:612289]: An autosomal dominant progeroid disorder characterized by prenatal and postnatal growth retardation, decreased subcutaneous fat tissue, wrinkled skin, an aged appearance since birth, an abnormal scalp hair pattern, sparse hair, hypoplastic distal phalanges with hypoplastic nails, a widely open anterior fontanel, facial dysmorphisms, and craniosynostosis. Early death is observed in some patients. {ECO:0000269 PubMed:29100093}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for SLC25A24

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with SLC25A24: view

No data available for Genatlas for SLC25A24 Gene

Publications for SLC25A24 Gene

  1. Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution. (PMID: 15123600) Fiermonte G … Palmieri F (The Journal of biological chemistry 2004) 2 3 4
  2. De Novo Mutations in SLC25A24 Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction. (PMID: 29100093) Ehmke N … Kornak U (American journal of human genetics 2017) 3 4
  3. A self-sequestered calmodulin-like Ca²⁺ sensor of mitochondrial SCaMC carrier and its implication to Ca²⁺-dependent ATP-Mg/P(i) transport. (PMID: 24332718) Yang Q … Chou JJ (Structure (London, England : 1993) 2014) 3 4
  4. SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca(2+) buffering. (PMID: 22015608) Traba J … Satrústegui J (Cell death and differentiation 2012) 3 4
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41

Products for SLC25A24 Gene

Sources for SLC25A24 Gene