Aliases for SLC25A22 Gene
External Ids for SLC25A22 Gene
Previous GeneCards Identifiers for SLC25A22 Gene
This gene encodes a mitochondrial glutamate carrier. Mutations in this gene are associated with early infantile epileptic encephalopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jul 2010]
GeneCards Summary for SLC25A22 Gene
SLC25A22 (Solute Carrier Family 25 Member 22) is a Protein Coding gene. Diseases associated with SLC25A22 include Developmental And Epileptic Encephalopathy 3 and Early Myoclonic Encephalopathy. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include symporter activity and L-glutamate transmembrane transporter activity. An important paralog of this gene is SLC25A18.
UniProtKB/Swiss-Prot Summary for SLC25A22 Gene
Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+).