Aliases for SLC25A10 Gene
External Ids for SLC25A10 Gene
Previous HGNC Symbols for SLC25A10 Gene
Previous GeneCards Identifiers for SLC25A10 Gene
This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
GeneCards Summary for SLC25A10 Gene
SLC25A10 (Solute Carrier Family 25 Member 10) is a Protein Coding gene. Diseases associated with SLC25A10 include Mitochondrial Dna Depletion Syndrome 19 and Mitochondrial Complex I Deficiency, Nuclear Type 1. Among its related pathways are Proximal tubule bicarbonate reclamation and Sulfur amino acid metabolism. Gene Ontology (GO) annotations related to this gene include antiporter activity and phosphate ion transmembrane transporter activity. An important paralog of this gene is ENSG00000262660.
UniProtKB/Swiss-Prot Summary for SLC25A10 Gene
Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane.