Aliases for SLC24A4 Gene
External Ids for SLC24A4 Gene
Previous GeneCards Identifiers for SLC24A4 Gene
This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
GeneCards Summary for SLC24A4 Gene
SLC24A4 (Solute Carrier Family 24 Member 4) is a Protein Coding gene. Diseases associated with SLC24A4 include Amelogenesis Imperfecta, Hypomaturation Type, Iia5 and Skin/Hair/Eye Pigmentation, Variation In, 6. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Visual Cycle in Retinal Rods. Gene Ontology (GO) annotations related to this gene include symporter activity and calcium, potassium:sodium antiporter activity. An important paralog of this gene is SLC24A3.
UniProtKB/Swiss-Prot Summary for SLC24A4 Gene
Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis (By similarity).