Aliases for SLC23A1 Gene
External Ids for SLC23A1 Gene
Previous HGNC Symbols for SLC23A1 Gene
Previous GeneCards Identifiers for SLC23A1 Gene
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
GeneCards Summary for SLC23A1 Gene
SLC23A1 (Solute Carrier Family 23 Member 1) is a Protein Coding gene. Diseases associated with SLC23A1 include Hypoascorbemia. Among its related pathways are Metabolism of water-soluble vitamins and cofactors and Metabolism. Gene Ontology (GO) annotations related to this gene include transporter activity and dehydroascorbic acid transmembrane transporter activity. An important paralog of this gene is SLC23A2.
UniProtKB/Swiss-Prot Summary for SLC23A1 Gene
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.