Aliases for SLC23A1 Gene
External Ids for SLC23A1 Gene
Previous HGNC Symbols for SLC23A1 Gene
Previous GeneCards Identifiers for SLC23A1 Gene
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
GeneCards Summary for SLC23A1 Gene
SLC23A1 (Solute Carrier Family 23 Member 1) is a Protein Coding gene. Diseases associated with SLC23A1 include Hypoascorbemia. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. Gene Ontology (GO) annotations related to this gene include transporter activity and dehydroascorbic acid transmembrane transporter activity. An important paralog of this gene is SLC23A2.
UniProtKB/Swiss-Prot for SLC23A1 Gene
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.