Aliases for SLC22A20P Gene

Aliases for SLC22A20P Gene

  • Solute Carrier Family 22 Member 20, Pseudogene 2 3 5
  • Solute Carrier Family 22, Member 20 2 3
  • Solute Carrier Family 22 Member 20 2 4
  • Organic Anion Transporter 6 3 4
  • SLC22A20 3 4
  • Oat6 2 3
  • Solute Carrier Family 22 Member 20 Pseudogene 4
  • SLC22A20P 5
  • FLJ16331 2
  • OAT6 4

External Ids for SLC22A20P Gene

Previous HGNC Symbols for SLC22A20P Gene

  • SLC22A20

Summaries for SLC22A20P Gene

GeneCards Summary for SLC22A20P Gene

SLC22A20P (Solute Carrier Family 22 Member 20, Pseudogene) is a Pseudogene.

UniProtKB/Swiss-Prot Summary for SLC22A20P Gene

  • Organic anion transporter that mediates the uptake of estrone sulfate. Inhibited by probenecid, propionate, 2-methylbutyrate, 3-methylbutyrate, benzoate, heptanoate and 2-ethylhaxanoate. May act as an odorant transporter (By similarity).

Additional gene information for SLC22A20P Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLC22A20P Gene

Genomics for SLC22A20P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SLC22A20P Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLC22A20P on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SLC22A20P

Genomic Locations for SLC22A20P Gene

Genomic Locations for SLC22A20P Gene
chr11:65,213,840-65,242,757
(GRCh38/hg38)
Size:
28,918 bases
Orientation:
Plus strand
chr11:64,981,311-65,010,228
(GRCh37/hg19)
Size:
28,918 bases
Orientation:
Plus strand

Genomic View for SLC22A20P Gene

Genes around SLC22A20P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC22A20P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC22A20P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC22A20P Gene

Proteins for SLC22A20P Gene

  • Protein details for SLC22A20P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NK97-S22AK_HUMAN
    Recommended name:
    Solute carrier family 22 member 20
    Protein Accession:
    A6NK97
    Secondary Accessions:
    • B9EJB2
    • Q6ZN88

    Protein attributes for SLC22A20P Gene

    Size:
    555 amino acids
    Molecular mass:
    60459 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAD18487.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for SLC22A20P Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC22A20P Gene

Post-translational modifications for SLC22A20P Gene

  • Glycosylation at Asn54 and Asn114
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for SLC22A20P Gene

Domains & Families for SLC22A20P Gene

Gene Families for SLC22A20P Gene

Protein Domains for SLC22A20P Gene

Suggested Antigen Peptide Sequences for SLC22A20P Gene

GenScript: Design optimal peptide antigens:
  • Organic anion transporter 6 (S22AK_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A6NK97

UniProtKB/Swiss-Prot:

S22AK_HUMAN :
  • Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Family:
  • Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
genes like me logo Genes that share domains with SLC22A20P: view

Function for SLC22A20P Gene

Molecular function for SLC22A20P Gene

UniProtKB/Swiss-Prot Function:
Organic anion transporter that mediates the uptake of estrone sulfate. Inhibited by probenecid, propionate, 2-methylbutyrate, 3-methylbutyrate, benzoate, heptanoate and 2-ethylhaxanoate. May act as an odorant transporter (By similarity).

Phenotypes From GWAS Catalog for SLC22A20P Gene

Gene Ontology (GO) - Molecular Function for SLC22A20P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0022857 transmembrane transporter activity IEA --
genes like me logo Genes that share ontologies with SLC22A20P: view
genes like me logo Genes that share phenotypes with SLC22A20P: view

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC22A20P

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLC22A20P Gene

Localization for SLC22A20P Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC22A20P Gene

Membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC22A20P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC22A20P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SLC22A20P Gene

Pathways & Interactions for SLC22A20P Gene

PathCards logo

SuperPathways for SLC22A20P Gene

No Data Available

Interacting Proteins for SLC22A20P Gene

Selected Interacting proteins: A6NK97-S22AK_HUMAN for SLC22A20P Gene via IID

Symbol External ID(s) Details
NDUFA13

Gene Ontology (GO) - Biological Process for SLC22A20P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006811 ion transport IEA --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC22A20P: view

No data available for Pathways by source and SIGNOR curated interactions for SLC22A20P Gene

Drugs & Compounds for SLC22A20P Gene

No Compound Related Data Available

Transcripts for SLC22A20P Gene

mRNA/cDNA for SLC22A20P Gene

1 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SLC22A20P Gene

No ASD Table

Relevant External Links for SLC22A20P Gene

GeneLoc Exon Structure for
SLC22A20P

Expression for SLC22A20P Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLC22A20P

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC22A20P Gene

Orthologs for SLC22A20P Gene

Evolution for SLC22A20P Gene

ENSEMBL:
Gene Tree for SLC22A20P (if available)
TreeFam:
Gene Tree for SLC22A20P (if available)

No data available for Orthologs for SLC22A20P Gene

Paralogs for SLC22A20P Gene

No data available for Paralogs for SLC22A20P Gene

Variants for SLC22A20P Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SLC22A20P Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type
rs11605576 - p.Ala58Asp
rs12420456 - p.Ala139Val

Structural Variations from Database of Genomic Variants (DGV) for SLC22A20P Gene

Variant ID Type Subtype PubMed ID
dgv666n106 CNV deletion 24896259
nsv1069594 CNV deletion 25765185
nsv526181 CNV gain 19592680
nsv832190 CNV loss 17160897
nsv951015 CNV deletion 24416366

Additional Variant Information for SLC22A20P Gene

Human Gene Mutation Database (HGMD)
SLC22A20P
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC22A20P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Additional dbSNP identifiers (rs#s) and Variation tolerance for SLC22A20P Gene

Disorders for SLC22A20P Gene

No disorders were found for SLC22A20P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC22A20P Gene

Publications for SLC22A20P Gene

  1. Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20). (PMID: 16478971) Schnabolk GW … Sweet DH (American journal of physiology. Renal physiology 2006) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  3. Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa. (PMID: 15369770) Monte JC … Nigam SK (Biochemical and biophysical research communications 2004) 2 3
  4. TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex. (PMID: 24344204) Guarani V … Harper JW (Molecular and cellular biology 2014) 3
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for SLC22A20P Gene

Sources for SLC22A20P Gene