Aliases for SLC1A7 Gene
External Ids for SLC1A7 Gene
Previous GeneCards Identifiers for SLC1A7 Gene
GeneCards Summary for SLC1A7 Gene
SLC1A7 (Solute Carrier Family 1 Member 7) is a Protein Coding gene. Diseases associated with SLC1A7 include Hartnup Disorder and Extrahepatic Bile Duct Adenocarcinoma. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Neurotransmitter Release Cycle. Gene Ontology (GO) annotations related to this gene include L-glutamate transmembrane transporter activity and sodium:dicarboxylate symporter activity. An important paralog of this gene is SLC1A3.
UniProtKB/Swiss-Prot Summary for SLC1A7 Gene
Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.
Glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1), widely distributed throughout the brain. There are five EAAT subtypes, each with a specific distribution.