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The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotra... See more...
Aliases for SLC17A7 Gene
Aliases for SLC17A7 Gene
External Ids for SLC17A7 Gene
- HGNC: 16704
- Entrez Gene: 57030
- Ensembl: ENSG00000104888
- OMIM: 605208
- UniProtKB: Q9P2U7
Previous GeneCards Identifiers for SLC17A7 Gene
- GC19M050591
- GC19M050301
- GC19M054608
- GC19M054624
- GC19M049933
- GC19M046309
- GC19M049934
Summaries for SLC17A7 Gene
-
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008]
GeneCards Summary for SLC17A7 Gene
SLC17A7 (Solute Carrier Family 17 Member 7) is a Protein Coding gene. Diseases associated with SLC17A7 include Deafness, Autosomal Dominant 25 and Kaufman Oculocerebrofacial Syndrome. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Neuroscience. Gene Ontology (GO) annotations related to this gene include L-glutamate transmembrane transporter activity and inorganic phosphate transmembrane transporter activity. An important paralog of this gene is SLC17A6.
UniProtKB/Swiss-Prot Summary for SLC17A7 Gene
-
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
Additional gene information for SLC17A7 Gene
- HGNC(16704)
- Entrez Gene(57030)
- Ensembl(ENSG00000104888)
- OMIM(605208)
- UniProtKB(Q9P2U7)
- Open Targets Platform(ENSG00000104888)
- Monarch Initiative
- Search for SLC17A7 at DataMed
- Search for SLC17A7 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLC17A7 Gene
Genomics for SLC17A7 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SLC17A7 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SLC17A7 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SLC17A7
- Top Transcription factor binding sites by QIAGEN in the SLC17A7 gene promoter:
-
- C/EBPbeta
- E47
- HOXA5
- ITF-2
- MRF-2
- MZF-1
- Pax-2
- Pax-2b
- Pax-5
- Tal-1beta
Genomic Locations for SLC17A7 Gene
Genomic Locations for SLC17A7 Gene
- chr19:49,429,401-49,442,360
- (GRCh38/hg38)
- Size:
- 12,960 bases
- Orientation:
- Minus strand
- chr19:49,932,655-49,945,617
- (GRCh37/hg19)
- Size:
- 12,963 bases
- Orientation:
- Minus strand
Genomic View for SLC17A7 Gene
Genes around SLC17A7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by HGNC
- 19q13.33 by Entrez Gene
- 19q13.33 by Ensembl
SLC17A7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SLC17A7 Gene
Proteins for SLC17A7 Gene
-
Protein details for SLC17A7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9P2U7-VGLU1_HUMAN
- Recommended name:
- Vesicular glutamate transporter 1
- Protein Accession:
- Q9P2U7
- B4DFR9
- B4DG46
- Q6PCD0
Protein attributes for SLC17A7 Gene
- Size:
- 560 amino acids
- Molecular mass:
- 61613 Da
- Quaternary structure:
-
- Interacts with SHANK3.
Protein Expression for SLC17A7 Gene
Post-translational modifications for SLC17A7 Gene
Other Protein References for SLC17A7 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-SLC17A7 monoclonal antibody, clone NdLB2
- Creative Biolabs Recombinant Anti-Human SLC17A7 Antibody
-
Custom Antibody ServicesOriGene Antibodies for SLC17A7
- Novus Biologicals Antibodies for SLC17A7
-
Abcam antibodies for SLC17A7
- Invitrogen Antibodies for SLC17A7 (AFLGC-SLC17A7)
-
Santa Cruz Biotechnology (SCBT) Antibodies for SLC17A7
- Sino Biological Antibodies for SLC17A7
Protein Products
-
OriGene Purified Proteins for SLC17A7
- Search Origene for MassSpec and Protein Over-expression Lysates for SLC17A7
- Origene Custom Protein Services for SLC17A7
- Novus Biologicals proteins for SLC17A7
- antibodies-online: Show 4 available SLC17A7 Proteins ranked by validation data
- Compare Top SLC17A7 Proteins
-
Quality Products:
-
Abcam proteins for SLC17A7
Assay Products
- antibodies-online: Show 7 available SLC17A7 Elisa Kits ranked by validation data
- Compare Top SLC17A7 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SLC17A7 Gene
Domains & Families for SLC17A7 Gene
Gene Families for SLC17A7 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Transporters
Protein Domains for SLC17A7 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SLC17A7 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ59680, highly similar to Homo sapiens solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, mRNA (B4DG46_HUMAN)
- Solute carrier family 17 member 7 (VGLU1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9P2U7UniProtKB/Swiss-Prot:
VGLU1_HUMAN :- Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
- Family:
-
- Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
Function for SLC17A7 Gene
Molecular function for SLC17A7 Gene
- UniProtKB/Swiss-Prot Function:
- Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
Phenotypes From GWAS Catalog for SLC17A7 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005313 | L-glutamate transmembrane transporter activity | TAS | -- |
| GO:0005315 | inorganic phosphate transmembrane transporter activity | IEA | -- |
| GO:0005326 | neurotransmitter transporter activity | IBA | 21873635 |
| GO:0005436 | sodium:phosphate symporter activity | TAS | 8632143 |
| GO:0008068 | extracellularly glutamate-gated chloride channel activity | IEA | -- |
Phenotypes for SLC17A7 Gene
- MGI mutant phenotypes for SLC17A7:
- inferred from 6 alleles
- GenomeRNAi human phenotypes for SLC17A7:
-
- no effect
- Decreased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Decreased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis
- Synthetic lethal with Ras
- Increased gamma-H2AX phosphorylation
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
Animal Models for SLC17A7 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for SLC17A7
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SLC17A7 - Select products 50% OFF >
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-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for SLC17A7
miRNA for SLC17A7 Gene
- miRTarBase miRNAs that target SLC17A7
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SLC17A7
- Browse OriGene Inhibitory RNA Products For SLC17A7
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Clone Products
- Applied Biological Materials (abm): Clones for SLC17A7 - Select products 50% OFF >
- * SLC17A7 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for SLC17A7
- Addgene plasmids for SLC17A7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SLC17A7
Cell Line Products
-
Horizon Cell Lines for SLC17A7
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SLC17A7 Gene
Localization for SLC17A7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SLC17A7 Gene
- Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane. Multi-pass membrane protein. Cell junction, synapse, synaptosome.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| endosome | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005623 | cell | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0008021 | synaptic vesicle | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA,IDA | 10820226 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SLC17A7 Gene
Pathways & Interactions for SLC17A7 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||
| 2 | Synaptic vesicle cycle | ||
| 3 | Neurotransmitter Release Cycle | ||
| 4 | Transmission across Chemical Synapses |
.62
|
|
| 5 | Neuroscience | ||
Pathways by source for SLC17A7 Gene
1 BioSystems pathway for SLC17A7 Gene
8 Reactome pathways for SLC17A7 Gene
4 KEGG pathways for SLC17A7 Gene
1 R&D Systems pathway for SLC17A7 Gene
1 Cell Signaling Technology pathway for SLC17A7 Gene
Interacting Proteins for SLC17A7 Gene
GPS-Prot Interaction Network for SLC17A7
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003407 | neural retina development | IEA | -- |
| GO:0006811 | ion transport | TAS | -- |
| GO:0006814 | sodium ion transport | IEA | -- |
| GO:0006817 | phosphate ion transport | TAS,IEA | -- |
| GO:0006820 | anion transport | IBA | 21873635 |
No data available for SIGNOR curated interactions for SLC17A7 Gene
Transcripts for SLC17A7 Gene
mRNA/cDNA for SLC17A7 Gene
- 1 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000221485 2949 nts (view in UCSC)
- ENST00000596689 553 nts (view in UCSC)
- ENST00000598018 2785 nts (view in UCSC)
- ENST00000600601 2237 nts (view in UCSC)
- ENST00000600672 2024 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SLC17A7 - Select products 50% OFF >
- * SLC17A7 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SLC17A7
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SLC17A7
-
Santa Cruz Biotechnology (SCBT) CRISPR for SLC17A7
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SLC17A7
- Browse OriGene Inhibitory RNA Products For SLC17A7
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC17A7
Clone Products
- Applied Biological Materials (abm): Clones for SLC17A7 - Select products 50% OFF >
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- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SLC17A7
- Addgene plasmids for SLC17A7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SLC17A7
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP5: | - | - |
Relevant External Links for SLC17A7 Gene
- GeneLoc Exon Structure for
- SLC17A7
Expression for SLC17A7 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Neurons
- Mature Rod Cells Outer Nuclear Layer
- BAMN-induced neuron-like cells(Pang ZP et. al. 2011)
-
Eye (Sensory Organs)
- Mature Rod Cells Outer Nuclear Layer
mRNA differential expression in normal tissues according to GTEx for SLC17A7 Gene
This gene is overexpressed in Brain - Cortex (x9.5), Brain - Anterior cingulate cortex (BA24) (x8.9), Brain - Frontal Cortex (BA9) (x8.4), Brain - Hippocampus (x7.9), Brain - Amygdala (x6.5), Brain - Cerebellum (x4.5), and Brain - Cerebellar Hemisphere (x4.5).
This gene is overexpressed in Frontal cortex (43.4), Brain (16.2), and Retina (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SLC17A7 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLC17A7
SOURCE GeneReport for Unigene cluster for SLC17A7 Gene:
Hs.375616mRNA Expression by UniProt/SwissProt for SLC17A7 Gene:
Q9P2U7-VGLU1_HUMAN
Tissue specificity:
Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.
Evidence on tissue expression from TISSUES for SLC17A7 Gene
- Nervous system(5)
- Eye(3.7)
- Skin(2.6)
- Heart(2.1)
- Muscle(2.1)
- Kidney(2.1)
Primer Products
-
OriGene qPCR primer pairs for SLC17A7
-
OriGene qPCR primer pairs and template standards for SLC17A7
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC17A7 Gene
Orthologs for SLC17A7 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SLC17A7 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SLC17A7 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SLC17A7 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Slc17a7 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Slc17a7 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | SLC17A7 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SLC17A7 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | slc17a7 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | SLC17A7 (3 of 3) 31 |
|
OneToMany | |
| slc17a6b 31 |
|
OneToMany | |||
| slc17a7 30 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG9887 32 |
|
|
|
| VGlut 31 |
|
OneToMany | |||
| CG4288 32 |
|
|
|||
| CG6978 32 |
|
|
|||
| CG15096 32 |
|
|
|||
| Picot 32 |
|
|
|||
| CG3036 32 |
|
|
|||
| CG15094 32 |
|
|
|||
| CG9825 32 |
|
|
|||
| CG9826 32 |
|
|
|||
| CG9864 32 |
|
|
|||
| l(2)08717 32 |
|
|
|||
| CG30265 32 |
|
|
|||
| CG30272 32 |
|
|
|||
| CG4726 32 |
|
|
|||
| NaPi-T 32 |
|
|
|||
| CG3649 32 |
|
|
|||
| CG7881 32 |
|
|
|||
| CG8791 32 |
|
|
|||
| CG2003 32 |
|
|
|||
| BEST:CK02623 32 |
|
|
|||
| Worm (Caenorhabditis elegans) |
Secernentea | eat-4 30 31 |
|
ManyToMany | |
| T07A5.3 32 |
|
|
|||
| vglu-3 31 |
|
ManyToMany | |||
| vglu-2 31 |
|
ManyToMany | |||
| ZK54.1 32 |
|
|
|||
| F21F8.11 32 |
|
|
|||
| C02C2.4 32 |
|
|
|||
| T09B9.2 32 |
|
|
|||
| F12B6.2a 32 |
|
|
|||
| F12B6.2b 32 |
|
|
|||
| R10D12.1 32 |
|
|
|||
| K10H10.1 32 |
|
|
|||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | PHT4;1 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os01g0279700 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for SLC17A7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for SLC17A7 Gene
- ENSEMBL:
- Gene Tree for SLC17A7 (if available)
- TreeFam:
- Gene Tree for SLC17A7 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SLC17A7: view image
Paralogs for SLC17A7 Gene
Paralogs for SLC17A7 Gene
(8) SIMAP similar genes for SLC17A7 Gene using alignment to 5 proteins:
- VGLU1_HUMAN
- B4DFR9_HUMAN
- B4DG46_HUMAN
- L8EA60_HUMAN
- M0R1S5_HUMAN
Variants for SLC17A7 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SLC17A7 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 714893 | Benign: not provided | 49,436,724(-) | C/T | MISSENSE_VARIANT | |
| 722306 | Benign: not provided | 49,434,053(-) | G/A | INTRON_VARIANT | |
| 727740 | Benign: not provided | 49,430,690(-) | G/A | SYNONYMOUS_VARIANT | |
| 730241 | Benign: not provided | 49,435,203(-) | T/C | SYNONYMOUS_VARIANT | |
| 738168 | Benign: not provided | 49,433,716(-) | G/T | INTRON_VARIANT |
Residual Variation Intolerance Score:
22% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.74;
32.93% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SLC17A7 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SLC17A7
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC17A7 Gene
Disorders for SLC17A7 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| deafness, autosomal dominant 25 |
|
|
| kaufman oculocerebrofacial syndrome |
|
|
| kagami-ogata syndrome |
|
|
| schizophrenia |
|
|
| neuropathy, hereditary, with liability to pressure palsies |
|
|
Search SLC17A7 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SLC17A7
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for SLC17A7 Gene
Publications for SLC17A7 Gene
- Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter. (PMID: 10820226) Aihara Y … Takeda J (Journal of neurochemistry 2000) 2 3 4 23
- Resequencing and association study of vesicular glutamate transporter 1 gene (VGLUT1) with schizophrenia. (PMID: 19720501) Shen YC … Chen CH (Schizophrenia research 2009) 3 23 41
- Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PMID: 19086053) Gratacòs M … Psychiatric Genetics Network Group (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009) 3 41
- Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. (PMID: 19156168) Need AC … Goldstein DB (European journal of human genetics : EJHG 2009) 3 41
- Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease. (PMID: 17531353) Kashani A … El Mestikawy S (Neurobiology of aging 2008) 3 23
ExternalLinks
Products for SLC17A7 Gene
- Custom Antibody ServicesOriGene Antibodies for SLC17A7
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SLC17A7
- Search Origene for MassSpec and Protein Over-expression Lysates for SLC17A7
- Origene Custom Protein Services for SLC17A7
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SLC17A7
- Browse OriGene Inhibitory RNA Products For SLC17A7
- OriGene qPCR primer pairs for SLC17A7
- OriGene qPCR primer pairs and template standards for SLC17A7
- OriGene CRISPR knockouts for SLC17A7
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SLC17A7
- Sino Biological Human cDNA Clone for SLC17A7
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for SLC17A7
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SLC17A7
- Novus Biologicals proteins for SLC17A7
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SLC17A7
- Abcam proteins for SLC17A7
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse ELISA Kits
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for SLC17A7
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for SLC17A7 (AFLGC-SLC17A7)
- VectorBuilder Custom and pre-made DNA vectors for SLC17A7 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SLC17A7 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SLC17A7 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SLC17A7 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SLC17A7
- Addgene plasmids for SLC17A7
- antibodies-online: Show 54 available SLC17A7 Antibodies ranked by validation data
- Compare Top SLC17A7 Antibodies
- antibodies-online: Show 7 available SLC17A7 Elisa Kits ranked by validation data
- Compare Top SLC17A7 Elisa Kits
- Quality Products:
- antibodies-online: Show 4 available SLC17A7 Proteins ranked by validation data
- Compare Top SLC17A7 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for SLC17A7
- Search Santa Cruz Biotechnology (SCBT) for SLC17A7 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SLC17A7
- Horizon Cell Lines for SLC17A7
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SLC17A7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SLC17A7
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SLC17A7
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC17A7
Sources for SLC17A7 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB