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Aliases for SLC16A13 Gene

Aliases for SLC16A13 Gene

  • Solute Carrier Family 16 Member 13 2 3 4 5
  • Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 13 2 3
  • Monocarboxylic Acid Transporter 13 2 3
  • MCT 13 3 4
  • MCT13 3 4
  • Solute Carrier Family 16, Member 13 2
  • Monocarboxylate Transporter 13 3

External Ids for SLC16A13 Gene

Previous GeneCards Identifiers for SLC16A13 Gene

  • GC17P007140
  • GC17P006882
  • GC17P006883
  • GC17P006939

Summaries for SLC16A13 Gene

GeneCards Summary for SLC16A13 Gene

SLC16A13 (Solute Carrier Family 16 Member 13) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include symporter activity and monocarboxylic acid transmembrane transporter activity. An important paralog of this gene is SLC16A11.

UniProtKB/Swiss-Prot for SLC16A13 Gene

  • Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.

Additional gene information for SLC16A13 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC16A13 Gene

Genomics for SLC16A13 Gene

GeneHancer (GH) Regulatory Elements for SLC16A13 Gene

Promoters and enhancers for SLC16A13 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I007034 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 -0.1 -80 2.4 HDGF PKNOX1 SMAD1 MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 POLR2B GC17P007037 GC17M007037 SLC16A13 NEURL4 DVL2 WRAP53 POLR2A SNORD10 CNTROB SENP3
GH17I007177 Promoter/Enhancer 1.4 Ensembl ENCODE 11.3 +141.8 141774 1.7 ATF1 ARID4B SIN3A DMAP1 YY1 GLIS2 ZNF143 ATF7 SP3 SP5 GC17P007176 ASGR1 SLC16A11 ACADVL DLG4 SLC16A13 CTDNEP1 ELP5 MIR324 DVL2
GH17I007171 Enhancer 1.1 Ensembl ENCODE 11.3 +137.6 137605 4.2 FOXA2 SIN3A YBX1 GLI4 ZNF143 ZNF207 KLF7 ZNF548 KLF13 PAF1 DVL2 CNTROB CYB5D1 NEURL4 WRAP53 NLGN2 LOC100996842 SENP3 SNORD10 ELP5
GH17I006710 Promoter/Enhancer 1.9 EPDnew FANTOM5 Ensembl ENCODE 6 -323.6 -323555 3.8 FOXA2 ARID4B YBX1 ZNF48 YY1 TCF12 SLC30A9 GLIS2 ZNF207 ATF7 SLC13A5 ASGR1 ASGR2 DVL2 SNORD10 LOC100996842 SNORA48 WRAP53 SLC16A13 SLC16A11
GH17I007170 Enhancer 0.5 Ensembl 11.3 +135.0 135026 0.6 GATAD2A NFIL3 HLF CEBPG SLC16A11 ACADVL DLG4 SLC16A13 ELP5 CTDNEP1 DVL2 PHF23 GABARAP MIR324
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SLC16A13 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SLC16A13 gene promoter:

Genomic Locations for SLC16A13 Gene

Genomic Locations for SLC16A13 Gene
4,047 bases
Plus strand

Genomic View for SLC16A13 Gene

Genes around SLC16A13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC16A13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC16A13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC16A13 Gene

Proteins for SLC16A13 Gene

  • Protein details for SLC16A13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Monocarboxylate transporter 13
    Protein Accession:
    Secondary Accessions:
    • A3KMG3
    • A5PKU5
    • Q2VP92

    Protein attributes for SLC16A13 Gene

    426 amino acids
    Molecular mass:
    44992 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC16A13 Gene

Post-translational modifications for SLC16A13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC16A13 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC16A13 Gene

Domains & Families for SLC16A13 Gene

Gene Families for SLC16A13 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Potential drug targets
  • Predicted membrane proteins
  • Transporters

Protein Domains for SLC16A13 Gene


Suggested Antigen Peptide Sequences for SLC16A13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
genes like me logo Genes that share domains with SLC16A13: view

Function for SLC16A13 Gene

Molecular function for SLC16A13 Gene

UniProtKB/Swiss-Prot Function:
Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.

Phenotypes From GWAS Catalog for SLC16A13 Gene

Gene Ontology (GO) - Molecular Function for SLC16A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008028 monocarboxylic acid transmembrane transporter activity IBA --
GO:0015293 symporter activity IEA --
genes like me logo Genes that share ontologies with SLC16A13: view
genes like me logo Genes that share phenotypes with SLC16A13: view

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC16A13

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC16A13 Gene

Localization for SLC16A13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC16A13 Gene

Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SLC16A13 gene
Compartment Confidence
golgi apparatus 5
plasma membrane 4
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SLC16A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005794 Golgi apparatus IDA,IEA 24390345
GO:0005886 plasma membrane IEA --
GO:0005887 integral component of plasma membrane IBA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with SLC16A13: view

Pathways & Interactions for SLC16A13 Gene

SuperPathways for SLC16A13 Gene

No Data Available

Interacting Proteins for SLC16A13 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000309751 Q7RTY0-MOT13_HUMAN for SLC16A13 Gene via STRING UniProtKB IID

Gene Ontology (GO) - Biological Process for SLC16A13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:0015718 monocarboxylic acid transport IBA --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC16A13: view

No data available for Pathways by source and SIGNOR curated interactions for SLC16A13 Gene

Drugs & Compounds for SLC16A13 Gene

No Compound Related Data Available

Transcripts for SLC16A13 Gene

mRNA/cDNA for SLC16A13 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC16A13 Gene

Solute carrier family 16, member 13 (monocarboxylic acid transporter 13):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC16A13 Gene

No ASD Table

Relevant External Links for SLC16A13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC16A13 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SLC16A13 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC16A13 Gene

This gene is overexpressed in Liver (x14.8) and Kidney - Cortex (x5.3).

NURSA nuclear receptor signaling pathways regulating expression of SLC16A13 Gene:


SOURCE GeneReport for Unigene cluster for SLC16A13 Gene:

genes like me logo Genes that share expression patterns with SLC16A13: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC16A13 Gene

Orthologs for SLC16A13 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC16A13 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SLC16A13 33 34
  • 99.61 (n)
(Rattus norvegicus)
Mammalia Slc16a13 33
  • 88.58 (n)
(Mus musculus)
Mammalia Slc16a13 33 16 34
  • 88.18 (n)
(Bos Taurus)
Mammalia SLC16A13 33 34
  • 87.72 (n)
(Canis familiaris)
Mammalia SLC16A13 33 34
  • 86.12 (n)
(Monodelphis domestica)
Mammalia SLC16A13 34
  • 77 (a)
(Gallus gallus)
Aves SLC16A13 34
  • 44 (a)
(Anolis carolinensis)
Reptilia SLC16A13 34
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc16a13 33
  • 58.95 (n)
(Danio rerio)
Actinopterygii LOC793210 33
  • 57.99 (n)
SLC16A13 34
  • 43 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 27 (a)
Species where no ortholog for SLC16A13 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC16A13 Gene

Gene Tree for SLC16A13 (if available)
Gene Tree for SLC16A13 (if available)

Paralogs for SLC16A13 Gene

(9) SIMAP similar genes for SLC16A13 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC16A13: view

Variants for SLC16A13 Gene

Sequence variations from dbSNP and Humsavar for SLC16A13 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000378064 -- 7,037,293(+) G/T intron_variant
rs1000524384 -- 7,035,152(+) T/C upstream_transcript_variant
rs1000539158 -- 7,034,524(+) C/T upstream_transcript_variant
rs1000673284 -- 7,034,847(+) C/T upstream_transcript_variant
rs1000701209 -- 7,034,933(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SLC16A13 Gene

Variant ID Type Subtype PubMed ID
esv1405948 CNV deletion 17803354
esv2422288 CNV deletion 17116639
esv2665042 CNV deletion 23128226
esv2672389 CNV deletion 23128226
esv2715594 CNV deletion 23290073
esv3164902 CNV deletion 24192839
esv3554075 CNV deletion 23714750
nsv457659 CNV loss 19166990
nsv512475 CNV loss 21212237
nsv574322 CNV loss 21841781

Variation tolerance for SLC16A13 Gene

Residual Variation Intolerance Score: 58.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.08; 38.03% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SLC16A13 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC16A13 Gene

Disorders for SLC16A13 Gene


  • Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853]: A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the bodys own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. {ECO:0000269 PubMed:24390345}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Additional Disease Information for SLC16A13

No disorders were found for SLC16A13 Gene.

No data available for MalaCards and Genatlas for SLC16A13 Gene

Publications for SLC16A13 Gene

  1. Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. (PMID: 24390345) SIGMA Type 2 Diabetes Consortium … Altshuler D (Nature 2014) 3 4 58
  2. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. (PMID: 12739169) Halestrap AP … Meredith D (Pflugers Archiv : European journal of physiology 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. Genome-wide association study identifies three novel loci for type 2 diabetes. (PMID: 23945395) Hara K … Kadowaki T (Human molecular genetics 2014) 3 58

Products for SLC16A13 Gene

Sources for SLC16A13 Gene

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