Aliases for SLC15A2 Gene
External Ids for SLC15A2 Gene
Previous GeneCards Identifiers for SLC15A2 Gene
The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter found in the small intestine (Liu et al, 1995 [PubMed 7756356]).[supplied by OMIM, Feb 2011]
GeneCards Summary for SLC15A2 Gene
SLC15A2 (Solute Carrier Family 15 Member 2) is a Protein Coding gene. Diseases associated with SLC15A2 include Cerebritis and Coproporphyria, Hereditary. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include transporter activity and peptide:proton symporter activity. An important paralog of this gene is SLC15A1.
UniProtKB/Swiss-Prot Summary for SLC15A2 Gene
Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:7756356). Transports the dipeptide-like aminopeptidase inhibitor bestatin (By similarity). Can also transport the aminocephalosporin antibiotic cefadroxil (By similarity).