Free for academic non-profit institutions. Other users need a Commercial license
Aliases for SKA2 Gene
Aliases for SKA2 Gene
External Ids for SKA2 Gene
- HGNC: 28006
- NCBI Entrez Gene: 348235
- Ensembl: ENSG00000182628
- OMIM®: 616674
- UniProtKB/Swiss-Prot: Q8WVK7
Previous HGNC Symbols for SKA2 Gene
- FAM33A
Previous GeneCards Identifiers for SKA2 Gene
- GC17M054544
- GC17M057188
- GC17M052547
Summaries for SKA2 Gene
GeneCards Summary for SKA2 Gene
SKA2 (Spindle And Kinetochore Associated Complex Subunit 2) is a Protein Coding gene. Diseases associated with SKA2 include Post-Traumatic Stress Disorder and Klatskin's Tumor. Among its related pathways are Signaling by GPCR and Mitotic Prometaphase. Gene Ontology (GO) annotations related to this gene include microtubule binding.
UniProtKB/Swiss-Prot Summary for SKA2 Gene
-
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:17093495, PubMed:19289083, PubMed:23085020). Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint (PubMed:17093495). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:17093495, PubMed:19289083). In the complex, it is required for SKA1 localization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
Additional gene information for SKA2 Gene
- HGNC (28006)
- NCBI Entrez Gene (348235)
- Ensembl (ENSG00000182628)
- OMIM® (616674)
- UniProtKB/Swiss-Prot (Q8WVK7)
- Open Targets Platform(ENSG00000182628)
- Search for SKA2 at DataMed
- Search for SKA2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SKA2 Gene
Genomics for SKA2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SKA2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SKA2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SKA2
Genomic Locations for SKA2 Gene
Latest Assembly
- chr17:59,109,857-59,155,260
- (GRCh38/hg38)
- Size:
- 45,404 bases
- Orientation:
- Minus strand
Previous Assembly
- chr17:57,187,218-57,232,547
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 45,330 bases
- Orientation:
- Minus strand
- chr17:57,187,312-57,232,630
- (GRCh37/hg19 by Ensembl)
- Size:
- 45,319 bases
- Orientation:
- Minus strand
Genomic View for SKA2 Gene
Genes around SKA2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q23.2 by HGNC
- 17q22 by Entrez Gene
- 17q22 by Ensembl
SKA2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SKA2 Gene
Proteins for SKA2 Gene
-
Protein details for SKA2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WVK7-SKA2_HUMAN
- Recommended name:
- Spindle and kinetochore-associated protein 2
- Protein Accession:
- Q8WVK7
- A6NIL3
- B3KPL3
- E9PCB8
Protein attributes for SKA2 Gene
- Size:
- 121 amino acids
- Molecular mass:
- 14188 Da
- Quaternary structure:
-
- Component of the SKA1 complex, composed of SKA1, SKA2 and SKA3. Forms a heterodimer with SKA1; the heterodimer interacting with SKA3. The core SKA1 complex is composed of 2 SKA1-SKA2 heterodimers, each heterodimer interacting with a molecule of the SKA3 homodimer. The core SKA1 complex associates with microtubules and forms oligomeric assemblies. Interacts directly with SKA1. Binds directly to microtubules; but with a much lower affinity than SKA1. May interact with NR3C1; the relevance of such interaction remains unclear in vivo.
Protein Expression for SKA2 Gene
Post-translational modifications for SKA2 Gene
Other Protein References for SKA2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences SKA2 Antibody
-
Custom Antibody ServicesOriGene Antibodies for SKA2
- Novus Biologicals Antibodies for SKA2
-
Abcam antibodies for SKA2
- Invitrogen Antibodies for SKA2 (AFLGC-SKA2)
-
Biorbyt antibodies for SKA2
-
Custom Antibody ServicesProSci Antibodies for SKA2
-
Santa Cruz Biotechnology (SCBT) Antibodies for SKA2
Protein products for research
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SKA2
- Origene Custom Protein Services for SKA2
- Novus Biologicals proteins for SKA2
-
Abcam proteins for SKA2
Assay products for research
- antibodies-online: Show 2 available FAM33A Elisa Kits ranked by validation data
- Compare Top FAM33A Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SKA2 Gene
Domains & Families for SKA2 Gene
Gene Families for SKA2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for SKA2 Gene
- GenScript: Design optimal peptide antigens:
-
- Family with sequence similarity 33 member A (C0KZE1_HUMAN)
- Protein FAM33A (SKA2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8WVK7- Family:
-
- Belongs to the SKA2 family.
Function for SKA2 Gene
Molecular function for SKA2 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:17093495, PubMed:19289083, PubMed:23085020). Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint (PubMed:17093495). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:17093495, PubMed:19289083). In the complex, it is required for SKA1 localization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
Phenotypes From GWAS Catalog for SKA2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 17093495 |
| GO:0008017 | microtubule binding | IEA,IDA | 19289083 |
Phenotypes for SKA2 Gene
- MGI mutant phenotypes for SKA2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SKA2:
-
- Increased gamma-H2AX phosphorylation
- Mitotic spindle defects
- no effect
- Decreased viability
- Decreased shRNA abundance (Z-score < -2)
- Effect on mitosis
- Increased shRNA abundance (Z-score > 2)
- Increased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Metaphase cells
- Decreased centriole number
Animal Models for SKA2 Gene
- MGI Knock Outs for SKA2:
-
- Ska2 Ska2<tm1b(KOMP)Wtsi>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SKA2 - Starting at $85 >
- * SKA2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SKA2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SKA2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SKA2
miRNA for SKA2 Gene
- miRTarBase miRNAs that target SKA2
-
- hsa-miR-375 (MIRT019891)
- hsa-let-7e-5p (MIRT051441)
- hsa-miR-153-3p (MIRT543109)
- hsa-miR-580-3p (MIRT543110)
- hsa-miR-6770-5p (MIRT543111)
- hsa-miR-1253 (MIRT543112)
- hsa-miR-4461 (MIRT543113)
- hsa-miR-3123 (MIRT543114)
- hsa-miR-3976 (MIRT543115)
- hsa-miR-3925-5p (MIRT543116)
- hsa-miR-519c-3p (MIRT543117)
- hsa-miR-519b-3p (MIRT543118)
- hsa-miR-519a-3p (MIRT543119)
- hsa-miR-7-2-3p (MIRT543120)
- hsa-miR-7-1-3p (MIRT543121)
- hsa-miR-3646 (MIRT543122)
- hsa-miR-4446-5p (MIRT715755)
- hsa-miR-5006-3p (MIRT715756)
- hsa-miR-4755-5p (MIRT715757)
- hsa-miR-642a-5p (MIRT715758)
- hsa-miR-3160-5p (MIRT715759)
- hsa-miR-1283 (MIRT715760)
- hsa-miR-2276-5p (MIRT715761)
- hsa-miR-6892-3p (MIRT715762)
- hsa-miR-548o-3p (MIRT715763)
- hsa-miR-1323 (MIRT715764)
- hsa-miR-548av-3p (MIRT715765)
- hsa-miR-548f-3p (MIRT715766)
- hsa-miR-548e-3p (MIRT715767)
- hsa-miR-548az-3p (MIRT715768)
- hsa-miR-548ar-3p (MIRT715769)
- hsa-miR-548a-3p (MIRT715770)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SKA2
- Browse OriGene Inhibitory RNA Products For SKA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SKA2
Clone products for research
- Applied Biological Materials (abm): Clones for SKA2 - Starting at $45 >
- * SKA2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for SKA2
- Addgene plasmids for SKA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SKA2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SKA2 Gene
Localization for SKA2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SKA2 Gene
- Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins. {ECO:0000269 PubMed:17093495, ECO:0000269 PubMed:19289083}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 5 |
| nucleus | 3 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000775 | chromosome, centromeric region | IEA | -- |
| GO:0000776 | kinetochore | IEA | -- |
| GO:0000777 | condensed chromosome kinetochore | IEA | -- |
| GO:0000940 | condensed chromosome outer kinetochore | IEA,IDA | 17093495 |
| GO:0005694 | chromosome | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SKA2 Gene
Pathways & Interactions for SKA2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell Cycle, Mitotic |
.83
|
.60
|
| 2 | Mitotic Metaphase and Anaphase |
.94
|
|
| 3 | Mitotic Prometaphase | ||
| 4 | Signaling by Rho GTPases | ||
| 5 | Signaling by GPCR | ||
Pathways by source for SKA2 Gene
12 Reactome pathways for SKA2 Gene
Interacting Proteins for SKA2 Gene
Selected Interacting proteins:
Q8WVK7-SKA2_HUMAN
ENSP00000333433
for SKA2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for SKA2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000278 | mitotic cell cycle | IMP | 19289083 |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007059 | chromosome segregation | IEA,IMP | 19289083 |
| GO:0031110 | regulation of microtubule polymerization or depolymerization | IDA | 19289083 |
| GO:0051301 | cell division | IEA,IMP | 17093495 |
No data available for SIGNOR curated interactions for SKA2 Gene
Transcripts for SKA2 Gene
mRNA/cDNA for SKA2 Gene
- 3 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000330137 2809 nts (view in UCSC)
- ENST00000437036 625 nts (view in UCSC)
- ENST00000578105 689 nts (view in UCSC)
- ENST00000578519 894 nts (view in UCSC)
- ENST00000580541 689 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SKA2 - Starting at $85 >
- * SKA2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SKA2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SKA2
-
Santa Cruz Biotechnology (SCBT) CRISPR for SKA2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SKA2
- Browse OriGene Inhibitory RNA Products For SKA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SKA2
Clone products for research
- Applied Biological Materials (abm): Clones for SKA2 - Starting at $45 >
- * SKA2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for SKA2
- Addgene plasmids for SKA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SKA2
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | · | 5f | · | 5g |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | ||||||||||||||||||||||||
| SP9: | - | - | - | - |
Relevant External Links for SKA2 Gene
- GeneLoc Exon Structure for
- SKA2
Expression for SKA2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Adipocyte (65.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SKA2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SKA2
SOURCE GeneReport for Unigene cluster for SKA2 Gene:
Hs.463607Evidence on tissue expression from TISSUES for SKA2 Gene
- Lung(4.4)
- Eye(4.1)
- Nervous system(3.9)
Primer products for research
-
OriGene qPCR primer pairs for SKA2
-
OriGene qPCR primer pairs and template standards for SKA2
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SKA2 Gene
Orthologs for SKA2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SKA2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SKA2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SKA2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Ska2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Ska2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | SKA2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SKA2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | SKA2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SKA2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ska2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | im:7140390 30 |
|
||
| SKA2 31 |
|
OneToOne |
- Species where no ortholog for SKA2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SKA2 Gene
- ENSEMBL:
- Gene Tree for SKA2 (if available)
- TreeFam:
- Gene Tree for SKA2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SKA2: view image
Paralogs for SKA2 Gene
(3) SIMAP similar genes for SKA2 Gene using alignment to 8 proteins:
- SKA2_HUMAN
- J3KRW9_HUMAN
- J3KRZ0_HUMAN
- J3KSP0_HUMAN
- J3KTC5_HUMAN
- J3QKN8_HUMAN
- J3QL03_HUMAN
- J3QS74_HUMAN
Pseudogenes.org Pseudogenes for SKA2 Gene
No data available for Paralogs for SKA2 Gene
Variants for SKA2 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3270n100 | CNV | gain | 25217958 |
| dgv3271n100 | CNV | gain | 25217958 |
| esv2758699 | CNV | gain | 17122850 |
| esv2761969 | CNV | loss | 21179565 |
| esv28194 | CNV | loss | 19812545 |
| esv3573764 | CNV | gain | 25503493 |
| esv990139 | CNV | deletion | 20482838 |
| nsv1065063 | CNV | gain | 25217958 |
| nsv575802 | CNV | loss | 21841781 |
| nsv833499 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
44.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.20;
4.42% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SKA2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SKA2
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SKA2 Gene
Disorders for SKA2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| post-traumatic stress disorder |
|
|
| klatskin's tumor |
|
|
| mulibrey nanism |
|
|
Search SKA2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SKA2
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for SKA2 Gene
Publications for SKA2 Gene
- The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility. (PMID: 19289083) Welburn JP … Cheeseman IM (Developmental cell 2009) 2 3 4
- Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor. (PMID: 18583474) Rice L … Ray DW (The Journal of endocrinology 2008) 2 3 4
- Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. (PMID: 17093495) Hanisch A … Nigg EA (The EMBO journal 2006) 2 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for SKA2 Gene
- Custom Antibody ServicesOriGene Antibodies for SKA2
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SKA2
- Origene Custom Protein Services for SKA2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SKA2
- Browse OriGene Inhibitory RNA Products For SKA2
- OriGene qPCR primer pairs for SKA2
- OriGene qPCR primer pairs and template standards for SKA2
- OriGene CRISPR knockouts for SKA2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SKA2
- Sino Biological Human cDNA Clone for SKA2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SKA2
- Novus Biologicals proteins for SKA2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SKA2
- Abcam proteins for SKA2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SKA2 (AFLGC-SKA2)
- VectorBuilder Custom and pre-made DNA vectors for SKA2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SKA2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SKA2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SKA2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SKA2
- Addgene plasmids for SKA2
- antibodies-online: Show 14 available FAM33A Antibodies ranked by validation data
- Compare Top FAM33A Antibodies
- antibodies-online: Show 2 available FAM33A Elisa Kits ranked by validation data
- Compare Top FAM33A Elisa Kits
- Quality Products:
- antibodies-online: Show 6 available FAM33A Proteins ranked by validation data
- Compare Top FAM33A Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for SKA2
- Search Santa Cruz Biotechnology (SCBT) for SKA2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SKA2
- Custom Antibody ServicesProSci Antibodies for SKA2
- Search for SKA2 Proteins at ProSci
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SKA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SKA2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SKA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SKA2
- Biorbyt antibodies for SKA2
Sources for SKA2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB