Aliases for SKA2 Gene
Aliases for SKA2 Gene
External Ids for SKA2 Gene
- HGNC: 28006
- Entrez Gene: 348235
- Ensembl: ENSG00000182628
- OMIM: 616674
- UniProtKB: Q8WVK7
Previous HGNC Symbols for SKA2 Gene
- FAM33A
Previous GeneCards Identifiers for SKA2 Gene
- GC17M054544
- GC17M057188
- GC17M052547
Summaries for SKA2 Gene
GeneCards Summary for SKA2 Gene
SKA2 (Spindle And Kinetochore Associated Complex Subunit 2) is a Protein Coding gene. Diseases associated with SKA2 include Post-Traumatic Stress Disorder. Among its related pathways are Cell Cycle, Mitotic and Mitotic Prometaphase. Gene Ontology (GO) annotations related to this gene include microtubule binding.
UniProtKB/Swiss-Prot Summary for SKA2 Gene
-
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:17093495, PubMed:19289083, PubMed:23085020). Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint (PubMed:17093495). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:17093495, PubMed:19289083). In the complex, it is required for SKA1 localization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SKA2 Gene
Genomics for SKA2 Gene
GeneHancer (GH) Regulatory Elements for SKA2 Gene
Promoters and enhancers for SKA2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SKA2 on UCSC Golden Path with GeneCards custom track
Genomic Locations for SKA2 Gene
Genomic Locations for SKA2 Gene
- chr17:59,109,857-59,155,439
- (GRCh38/hg38)
- Size:
- 45,583 bases
- Orientation:
- Minus strand
- chr17:57,187,308-57,232,800
- (GRCh37/hg19)
- Size:
- 45,493 bases
- Orientation:
- Minus strand
Genomic View for SKA2 Gene
Genes around SKA2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q23.2 by HGNC
- 17q22 by Entrez Gene
- 17q22 by Ensembl
SKA2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SKA2 Gene
Proteins for SKA2 Gene
-
Protein details for SKA2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WVK7-SKA2_HUMAN
- Recommended name:
- Spindle and kinetochore-associated protein 2
- Protein Accession:
- Q8WVK7
- A6NIL3
- B3KPL3
- E9PCB8
Protein attributes for SKA2 Gene
- Size:
- 121 amino acids
- Molecular mass:
- 14188 Da
- Quaternary structure:
-
- Component of the SKA1 complex, composed of SKA1, SKA2 and SKA3. Forms a heterodimer with SKA1; the heterodimer interacting with SKA3. The core SKA1 complex is composed of 2 SKA1-SKA2 heterodimers, each heterodimer interacting with a molecule of the SKA3 homodimer. The core SKA1 complex associates with microtubules and forms oligomeric assemblies. Interacts directly with SKA1. Binds directly to microtubules; but with a much lower affinity than SKA1. May interact with NR3C1; the relevance of such interaction remains unclear in vivo.
Protein Expression for SKA2 Gene
Post-translational modifications for SKA2 Gene
Other Protein References for SKA2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-SKA2 Antibody
-
Custom Antibody ServicesOriGene Antibodies for SKA2
- Novus Biologicals Antibodies for SKA2
-
Abcam antibodies for SKA2
- Invitrogen Antibodies for SKA2 (AFLGC-SKA2)
-
Biorbyt antibodies for SKA2
-
Custom Antibody ServicesProSci Antibodies for SKA2
-
Santa Cruz Biotechnology (SCBT) Antibodies for SKA2
Protein Products
- Atlas Antibodies PrEST Antigen SKA2
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SKA2
- Origene Custom Protein Services for SKA2
- Novus Biologicals proteins for SKA2
-
Abcam proteins for SKA2
Assay Products
- antibodies-online: Show 2 available FAM33A Elisa Kits ranked by validation data
- Compare Top FAM33A Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SKA2 Gene
Domains & Families for SKA2 Gene
Gene Families for SKA2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for SKA2 Gene
- GenScript: Design optimal peptide antigens:
-
- Family with sequence similarity 33 member A (C0KZE1_HUMAN)
- Protein FAM33A (SKA2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8WVK7- Family:
-
- Belongs to the SKA2 family.
Function for SKA2 Gene
Molecular function for SKA2 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:17093495, PubMed:19289083, PubMed:23085020). Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint (PubMed:17093495). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:17093495, PubMed:19289083). In the complex, it is required for SKA1 localization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
Phenotypes From GWAS Catalog for SKA2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 17093495 |
| GO:0008017 | microtubule binding | IDA,IEA | 19289083 |
Phenotypes for SKA2 Gene
- MGI mutant phenotypes for SKA2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SKA2:
-
- Decreased shRNA abundance (Z-score < -2)
- Effect on mitosis
- Dynamic nuclei (hole, folded or small irregular)
- Increased shRNA abundance (Z-score > 2)
- Increased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased centriole number
- Mitotic spindle defects
- Increased viability
- Lamellipodia cells
Animal Models for SKA2 Gene
- MGI Knock Outs for SKA2:
-
- Ska2 Ska2<tm1b(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SKA2 - Select products 50% OFF >
- * SKA2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SKA2 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for SKA2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SKA2
- genomics-online: gRNA clones - Search for available FAM33A gRNA products
- Overview of 100 available FAM33A gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SKA2
miRNA for SKA2 Gene
- miRTarBase miRNAs that target SKA2
-
- hsa-mir-375 (MIRT019891)
- hsa-let-7e-5p (MIRT051441)
- hsa-mir-153-3p (MIRT543109)
- hsa-mir-580-3p (MIRT543110)
- hsa-mir-6770-5p (MIRT543111)
- hsa-mir-1253 (MIRT543112)
- hsa-mir-4461 (MIRT543113)
- hsa-mir-3123 (MIRT543114)
- hsa-mir-3976 (MIRT543115)
- hsa-mir-3925-5p (MIRT543116)
- hsa-mir-519c-3p (MIRT543117)
- hsa-mir-519b-3p (MIRT543118)
- hsa-mir-519a-3p (MIRT543119)
- hsa-mir-7-2-3p (MIRT543120)
- hsa-mir-7-1-3p (MIRT543121)
- hsa-mir-3646 (MIRT543122)
- hsa-mir-4446-5p (MIRT715755)
- hsa-mir-5006-3p (MIRT715756)
- hsa-mir-4755-5p (MIRT715757)
- hsa-mir-642a-5p (MIRT715758)
- hsa-mir-3160-5p (MIRT715759)
- hsa-mir-1283 (MIRT715760)
- hsa-mir-2276-5p (MIRT715761)
- hsa-mir-6892-3p (MIRT715762)
- hsa-mir-548o-3p (MIRT715763)
- hsa-mir-1323 (MIRT715764)
- hsa-mir-548av-3p (MIRT715765)
- hsa-mir-548f-3p (MIRT715766)
- hsa-mir-548e-3p (MIRT715767)
- hsa-mir-548az-3p (MIRT715768)
- hsa-mir-548ar-3p (MIRT715769)
- hsa-mir-548a-3p (MIRT715770)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SKA2
- Browse OriGene Inhibitory RNA Products For SKA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SKA2
- genomics-online: shRNA clones - Search for available FAM33A shRNA products
- Overview of 100 available FAM33A gene related products
Clone Products
- Applied Biological Materials (abm): Clones for SKA2 - Select products 50% OFF >
- * SKA2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SKA2 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for SKA2
- Addgene plasmids for SKA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SKA2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SKA2 Gene
Localization for SKA2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SKA2 Gene
- Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins. {ECO:0000269 PubMed:17093495, ECO:0000269 PubMed:19289083}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 4 |
| nucleus | 1 |
| extracellular | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000775 | chromosome, centromeric region | IEA | -- |
| GO:0000776 | kinetochore | IEA | -- |
| GO:0000777 | condensed chromosome kinetochore | IEA | -- |
| GO:0000940 | condensed chromosome outer kinetochore | IEA,IDA | 17093495 |
| GO:0005694 | chromosome | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SKA2 Gene
Pathways & Interactions for SKA2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell Cycle, Mitotic |
.83
|
.60
|
| 2 | Mitotic Metaphase and Anaphase |
.94
|
|
| 3 | Mitotic Prometaphase | ||
| 4 | Signaling by Rho GTPases | ||
| 5 | Signaling by GPCR | ||
Pathways by source for SKA2 Gene
12 Reactome pathways for SKA2 Gene
Interacting Proteins for SKA2 Gene
Selected Interacting proteins:
Q8WVK7-SKA2_HUMAN
ENSP00000333433
for SKA2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for SKA2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000278 | mitotic cell cycle | IMP | 19289083 |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007059 | chromosome segregation | IMP,IEA | 19289083 |
| GO:0031110 | regulation of microtubule polymerization or depolymerization | IDA | 19289083 |
| GO:0051301 | cell division | IMP,IEA | 17093495 |
No data available for SIGNOR curated interactions for SKA2 Gene
Drugs & Compounds for SKA2 Gene
No Compound Related Data Available
Drug Products
- Atlas Antibodies PrEST Antigen SKA2
Transcripts for SKA2 Gene
mRNA/cDNA for SKA2 Gene
- (3) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (174) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000330137 2809 bps (ENST00000330137.11)
- ENST00000437036 625 bps (ENST00000437036.6)
- ENST00000578105 689 bps (ENST00000578105.1)
- ENST00000578519 894 bps (ENST00000578519.5)
- ENST00000580541 689 bps (ENST00000580541.1)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SKA2 - Select products 50% OFF >
- * SKA2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SKA2 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for SKA2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SKA2
- genomics-online: gRNA clones - Search for available FAM33A gRNA products
- Overview of 100 available FAM33A gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SKA2
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SKA2
- Browse OriGene Inhibitory RNA Products For SKA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SKA2
- genomics-online: shRNA clones - Search for available FAM33A shRNA products
- Overview of 100 available FAM33A gene related products
Clone Products
- Applied Biological Materials (abm): Clones for SKA2 - Select products 50% OFF >
- * SKA2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SKA2 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for SKA2
- Addgene plasmids for SKA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SKA2
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | · | 5f | · | 5g |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||
| SP7: | - | - | - | ||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | ||||||||||||||||||||||||
| SP9: | - | - | - | - |
Expression for SKA2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Adipocyte (65.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SKA2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SKA2 Gene:
SKA2SOURCE GeneReport for Unigene cluster for SKA2 Gene:
Hs.463607Evidence on tissue expression from TISSUES for SKA2 Gene
- Lung(4.3)
- Eye(4.1)
- Nervous system(3.7)
Primer Products
-
OriGene qPCR primer pairs for SKA2
-
OriGene qPCR primer pairs and template standards for SKA2
- genomics-online: primer clones - Search for available FAM33A Primer products
- Overview of 100 available FAM33A gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SKA2 Gene
Orthologs for SKA2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SKA2 33 32 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SKA2 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SKA2 33 32 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ska2 17 33 32 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ska2 32 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | SKA2 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SKA2 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | SKA2 33 32 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | SKA2 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ska2 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | im:7140390 32 |
|
||
| SKA2 33 |
|
OneToOne |
- Species where no ortholog for SKA2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for SKA2 Gene
- ENSEMBL:
- Gene Tree for SKA2 (if available)
- TreeFam:
- Gene Tree for SKA2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SKA2: view image
Paralogs for SKA2 Gene
(3) SIMAP similar genes for SKA2 Gene using alignment to 8 proteins:
- SKA2_HUMAN
- J3KRW9_HUMAN
- J3KRZ0_HUMAN
- J3KSP0_HUMAN
- J3KTC5_HUMAN
- J3QKN8_HUMAN
- J3QL03_HUMAN
- J3QS74_HUMAN
Pseudogenes.org Pseudogenes for SKA2 Gene
No data available for Paralogs for SKA2 Gene
Variants for SKA2 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000014474 | -- | 59,123,900(-) | A/G | intron_variant | |
| rs1000042368 | -- | 59,115,073(-) | A/G/T | intron_variant | |
| rs1000058127 | -- | 59,132,317(-) | T/C | intron_variant | |
| rs1000108990 | -- | 59,113,389(-) | G/T | intron_variant | |
| rs1000114973 | -- | 59,120,878(-) | C/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3270n100 | CNV | gain | 25217958 |
| dgv3271n100 | CNV | gain | 25217958 |
| esv2758699 | CNV | gain | 17122850 |
| esv2761969 | CNV | loss | 21179565 |
| esv28194 | CNV | loss | 19812545 |
| esv3573764 | CNV | gain | 25503493 |
| esv990139 | CNV | deletion | 20482838 |
| nsv1065063 | CNV | gain | 25217958 |
| nsv575802 | CNV | loss | 21841781 |
| nsv833499 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
44.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.20;
4.42% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SKA2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SKA2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SKA2 Gene
Disorders for SKA2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| post-traumatic stress disorder |
|
|
Search SKA2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SKA2
No data available for UniProtKB/Swiss-Prot and Genatlas for SKA2 Gene
Publications for SKA2 Gene
- The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility. (PMID: 19289083) Welburn JP … Cheeseman IM (Developmental cell 2009) 2 3 4 56
- Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor. (PMID: 18583474) Rice L … Ray DW (The Journal of endocrinology 2008) 2 3 4 56
- Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. (PMID: 17093495) Hanisch A … Nigg EA (The EMBO journal 2006) 2 3 4 56
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
ExternalLinks
Products for SKA2 Gene
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- Invitrogen Antibodies for SKA2 (AFLGC-SKA2)
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- antibodies-online: Show 14 available FAM33A Antibodies ranked by validation data
- Compare Top FAM33A Antibodies
- antibodies-online: Show 2 available FAM33A Elisa Kits ranked by validation data
- Compare Top FAM33A Elisa Kits
- Quality Products:
- antibodies-online: Show 6 available FAM33A Proteins ranked by validation data
- Compare Top FAM33A Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for SKA2
- Search Santa Cruz Biotechnology (SCBT) for SKA2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SKA2
- Custom Antibody ServicesProSci Antibodies for SKA2
- Search for SKA2 Proteins at ProSci
- genomics-online: cdna clones - Search for available FAM33A CDNA products
- Overview of 100 available FAM33A gene related products
- orf clones - Search for available FAM33A ORF products
- Overview of 100 available FAM33A gene related products
- genomics-online: gRNA clones - Search for available FAM33A gRNA products
- Overview of 100 available FAM33A gene related products
- genomics-online: primer clones - Search for available FAM33A Primer products
- Overview of 100 available FAM33A gene related products
- genomics-online: shRNA clones - Search for available FAM33A shRNA products
- Overview of 100 available FAM33A gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SKA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SKA2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SKA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SKA2
- Biorbyt antibodies for SKA2
Sources for SKA2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource