Aliases for SIX5 Gene
Aliases for SIX5 Gene
External Ids for SIX5 Gene
- HGNC: 10891
- Entrez Gene: 147912
- Ensembl: ENSG00000177045
- OMIM: 600963
- UniProtKB: Q8N196
Previous HGNC Symbols for SIX5 Gene
- DMAHP
Previous GeneCards Identifiers for SIX5 Gene
- GC19U990028
- GC19M050959
- GC19M046268
- GC19M042696
Summaries for SIX5 Gene
-
The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2. [provided by RefSeq, Jul 2009]
GeneCards Summary for SIX5 Gene
SIX5 (SIX Homeobox 5) is a Protein Coding gene. Diseases associated with SIX5 include Branchiootorenal Syndrome 2 and Branchiootorenal Syndrome. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is SIX4.
UniProtKB/Swiss-Prot for SIX5 Gene
-
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity).
Additional gene information for SIX5 Gene
- Monarch Initiative
- Search for SIX5 at DataMed
- Search for SIX5 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SIX5 Gene
Genomics for SIX5 Gene
GeneHancer (GH) Regulatory Elements for SIX5 Gene
Promoters and enhancers for SIX5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SIX5 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the SIX5 gene promoter:
-
- AREB6
- CUTL1
- ITF-2
- Nkx2-5
- Roaz
- RSRFC4
- Sp1
- SRF
- SRF (504 AA)
- Tal-1beta
Genomic Locations for SIX5 Gene
Genomic Locations for SIX5 Gene
- chr19:45,764,785-45,769,252
- (GRCh38/hg38)
- Size:
- 4,468 bases
- Orientation:
- Minus strand
- chr19:46,268,043-46,272,497
- (GRCh37/hg19)
- Size:
- 4,455 bases
- Orientation:
- Minus strand
Genomic View for SIX5 Gene
Genes around SIX5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.32 by HGNC
- 19q13.32 by Entrez Gene
- 19q13.32 by Ensembl
SIX5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SIX5 Gene
Proteins for SIX5 Gene
-
Protein details for SIX5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N196-SIX5_HUMAN
- Recommended name:
- Homeobox protein SIX5
- Protein Accession:
- Q8N196
Protein attributes for SIX5 Gene
- Size:
- 739 amino acids
- Molecular mass:
- 74562 Da
- Quaternary structure:
-
- Probably binds DNA dimer. Interacts with EYA3, and probably EYA1 and EYA2 (By similarity).
- SequenceCaution:
-
- Sequence=AAH33204.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing.; Evidence={ECO:0000305}; Sequence=AK074826; Type=Erroneous termination; Positions=721; Note=Translated as Glu.; Evidence={ECO:0000305};
Protein Expression for SIX5 Gene
Post-translational modifications for SIX5 Gene
Other Protein References for SIX5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-SIX5 Antibody
-
Custom Antibody ServicesOriGene Antibodies for SIX5
- Novus Biologicals Antibodies for SIX5
-
Abcam antibodies for SIX5
- Invitrogen Antibodies for SIX5 (AFLGC-SIX5)
- antibodies-online: Search results for available Six5 related products ranked by validation data
-
Boster Bio Antibodies for SIX5
Protein Products
- Atlas Antibodies PrEST Antigen SIX5
-
OriGene Purified Proteins for SIX5
- Search Origene for MassSpec and Protein Over-expression Lysates for SIX5
- Origene Custom Protein Services for SIX5
- antibodies-online: Search results for available Six5 related products ranked by validation data
No data available for DME Specific Peptides for SIX5 Gene
Domains & Families for SIX5 Gene
Gene Families for SIX5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for SIX5 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SIX5 Gene
- GenScript: Design optimal peptide antigens:
-
- Sine oculis homeobox homolog 5 (SIX5_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8N196- Family:
-
- Belongs to the SIX/Sine oculis homeobox family.
Function for SIX5 Gene
Molecular function for SIX5 Gene
- UniProtKB/Swiss-Prot Function:
- Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity).
- GENATLAS Biochemistry:
- Drosophila sine oculis homolog SIX5,myotonic dystrophy (DM) locus-associated homeo box encoding gene,expressed in skeletal muscle,heart and brain,also expressed in eye,especially in lens epithelium,potentially involved in the development of adult onset cataracts frequently observed in DM,homolog to the muscle-specific transcription factor AREC3,inhibited in dystrophia myotonica by CTG repeat expansion in 3'-non-coding region of DMPK,abuting its own 5'end
Phenotypes From GWAS Catalog for SIX5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000976 | transcription regulatory region sequence-specific DNA binding | IBA | 21873635 |
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA | -- |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | NAS | 19274049 |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 16713569 |
Phenotypes for SIX5 Gene
- MGI mutant phenotypes for SIX5:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for SIX5:
-
- Decreased vesicular stomatitis virus (VSV) infection
- Negative genetic interaction between BLM-/- and BLM+/+
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Decreased viability in esophageal squamous lineage
- Decreased shRNA abundance
- Decreased viability
- no effect
- Decreased NF-kappaB reporter expression
- shRNA abundance <= 50%
- Decreased IL-8 secretion
- Increased viability
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SIX5
-
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SIX5 - Now 50% OFF >
- * SIX5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SIX5 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for SIX5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SIX5
- genomics-online: gRNA clones - Search results for available Six5 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SIX5
miRNA for SIX5 Gene
- miRTarBase miRNAs that target SIX5
-
- hsa-mir-26b-5p (MIRT029180)
- hsa-mir-6774-5p (MIRT486130)
- hsa-mir-3147 (MIRT486132)
- hsa-mir-4472 (MIRT486133)
- hsa-mir-4447 (MIRT486134)
- hsa-mir-6769b-5p (MIRT486135)
- hsa-mir-6769a-5p (MIRT486136)
- hsa-mir-92a-2-5p (MIRT486137)
- hsa-mir-541-3p (MIRT486138)
- hsa-mir-654-5p (MIRT486139)
- hsa-mir-6848-5p (MIRT486140)
- hsa-mir-6846-5p (MIRT486141)
- hsa-mir-4697-5p (MIRT486142)
- hsa-mir-4488 (MIRT486143)
- hsa-mir-1237-5p (MIRT486144)
- hsa-mir-6721-5p (MIRT486145)
- hsa-mir-7978 (MIRT486146)
- hsa-mir-3195 (MIRT486147)
- hsa-mir-4456 (MIRT486148)
- hsa-mir-548q (MIRT486149)
- hsa-mir-4299 (MIRT486150)
- hsa-mir-4259 (MIRT486151)
- hsa-mir-4749-3p (MIRT508300)
- hsa-mir-6824-3p (MIRT508301)
- hsa-mir-6764-3p (MIRT508302)
- hsa-mir-2276-5p (MIRT508303)
- hsa-mir-718 (MIRT653763)
- hsa-mir-572 (MIRT653764)
- hsa-mir-2355-5p (MIRT653765)
- hsa-mir-4669 (MIRT653766)
- hsa-mir-3657 (MIRT653767)
- hsa-mir-6811-3p (MIRT653768)
- hsa-mir-6832-3p (MIRT653769)
- hsa-mir-6769a-3p (MIRT653770)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SIX5
- Browse OriGene Inhibitory RNA Products For SIX5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SIX5
- genomics-online: shRNA clones - Search results for available Six5 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for SIX5 - Now 50% OFF >
- * SIX5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SIX5 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for SIX5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SIX5
- genomics-online: cdna clones - Search results for available Six5 gene related products
- orf clones - Search results for available Six5 gene related products
Cell Line Products
-
Horizon Cell Lines for SIX5
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for SIX5 Gene
Localization for SIX5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SIX5 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA,IEA | 21873635 |
| GO:0005667 | transcription factor complex | IBA | 21873635 |
| GO:0005737 | cytoplasm | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SIX5 Gene
Pathways & Interactions for SIX5 Gene
Interacting Proteins for SIX5 Gene
Selected Interacting proteins:
Q8N196-SIX5_HUMAN
ENSP00000316842
for SIX5 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SIX5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002088 | lens development in camera-type eye | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0007286 | spermatid development | IEA | -- |
| GO:0008285 | negative regulation of cell proliferation | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for SIX5 Gene
Drugs & Compounds for SIX5 Gene
No Compound Related Data Available
Drug Products
- Atlas Antibodies PrEST Antigen SIX5
Transcripts for SIX5 Gene
mRNA/cDNA for SIX5 Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (311) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000643139 2943 bps (ENST00000643139.1)
- ENST00000317578 3344 bps (ENST00000317578.6)
- ENST00000560160 1809 bps (ENST00000560160.1)
- ENST00000560168 1975 bps (ENST00000560168.1)
- ENST00000622857 1401 bps (ENST00000622857.1)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SIX5 - Now 50% OFF >
- * SIX5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SIX5 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for SIX5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SIX5
- genomics-online: gRNA clones - Search results for available Six5 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SIX5
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for SIX5
- Browse OriGene Inhibitory RNA Products For SIX5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SIX5
- genomics-online: shRNA clones - Search results for available Six5 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for SIX5 - Now 50% OFF >
- * SIX5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SIX5 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for SIX5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SIX5
- genomics-online: cdna clones - Search results for available Six5 gene related products
- orf clones - Search results for available Six5 gene related products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||
| SP2: | - |
Expression for SIX5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
This gene is overexpressed in Heart (48.5), Peripheral blood mononuclear cells (10.7), and Brain (8.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SIX5 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of SIX5 Gene:
SIX5SOURCE GeneReport for Unigene cluster for SIX5 Gene:
Hs.43314mRNA Expression by UniProt/SwissProt for SIX5 Gene:
Q8N196-SIX5_HUMAN
Tissue specificity:
Expressed in adult but not in fetal eyes. Found in corneal epithelium and endothelium, lens epithelium, ciliary body epithelia, cellular layers of the retina and the sclera.
Evidence on tissue expression from TISSUES for SIX5 Gene
- Eye(4.5)
- Heart(3)
- Blood(2.4)
- Kidney(2.4)
- Nervous system(2.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for SIX5 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- digestive
- endocrine
- immune
- integumentary
- nervous
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- cheek
- chin
- cranial nerve
- ear
- face
- head
- inner ear
- jaw
- lacrimal apparatus
- mandible
- maxilla
- middle ear
- mouth
- neck
- nose
- outer ear
- pharynx
- skull
- thyroid
- tongue
- tooth
Thorax:
- esophagus
Abdomen:
- biliary tract
- duodenum
- intestine
- kidney
- large intestine
- pancreas
- small intestine
- stomach
Pelvis:
- pelvis
- ureter
- urinary bladder
Limb:
- femur
- hip
- lower limb
- thigh
General:
- peripheral nerve
- peripheral nervous system
- skin
Primer Products
-
OriGene qPCR primer pairs for SIX5
- genomics-online: primer clones - Search results for available Six5 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues for SIX5 Gene
Orthologs for SIX5 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SIX5 35 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SIX5 35 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SIX5 35 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SIX5 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Six5 17 35 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Six5 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| zebrafish (Danio rerio) |
Actinopterygii | six4.3 35 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | Six4 35 |
|
OneToMany |
- Species where no ortholog for SIX5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for SIX5 Gene
- ENSEMBL:
- Gene Tree for SIX5 (if available)
- TreeFam:
- Gene Tree for SIX5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SIX5: view image
Paralogs for SIX5 Gene
Variants for SIX5 Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1003871860 | uncertain-significance, Steinert myotonic dystrophy syndrome | 45,770,541(-) | C/A/G | upstream_transcript_variant | |
| rs1057519372 | uncertain-significance, Branchiootorenal syndrome 2 | 45,766,698(-) | C/T | coding_sequence_variant, missense_variant | |
| rs2014576 | benign, not specified, - | 45,765,818(-) | G/A | coding_sequence_variant, missense_variant | |
| rs2341097 | benign, not specified, Branchiootorenal syndrome 2, - | 45,765,644(-) | C/T | coding_sequence_variant, missense_variant | |
| rs536277584 | uncertain-significance, Myotonic dystrophy | 45,771,011(-) | G/A/C | upstream_transcript_variant |
Gene Damage Index Score:
8.76;
86.70% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SIX5 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SIX5 Gene
Disorders for SIX5 Gene
(8) MalaCards diseases for SIX5 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| branchiootorenal syndrome 2 |
|
|
| branchiootorenal syndrome |
|
|
| myotonic dystrophy |
|
|
| branchiootic syndrome |
|
|
| lacrimal duct obstruction |
|
|
Search SIX5 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
SIX5_HUMAN- Branchiootorenal syndrome 2 (BOR2) [MIM:610896]: A syndrome characterized by branchial cleft fistulas or cysts, sensorineural and/or conductive hearing loss, pre-auricular pits, structural defects of the outer, middle or inner ear, and renal malformations. {ECO:0000269 PubMed:17357085}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for SIX5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for SIX5 Gene
Publications for SIX5 Gene
- A novel homeodomain-encoding gene is associated with a large CpG island interrupted by the myotonic dystrophy unstable (CTG)n repeat. (PMID: 8595416) Boucher CA … Chartier FL (Human molecular genetics 1995) 2 3 4 23 58
- Transcription factor SIX5 is mutated in patients with branchio-oto-renal syndrome. (PMID: 17357085) Hoskins BE … Hildebrandt F (American journal of human genetics 2007) 3 4 23 58
- Six and Eya expression during human somitogenesis and MyoD gene family activation. (PMID: 12500905) Fougerousse F … Maire P (Journal of muscle research and cell motility 2002) 3 4 23 58
- Characterization of the expression of DMPK and SIX5 in the human eye and implications for pathogenesis in myotonic dystrophy. (PMID: 9949207) Winchester CL … Johnson KJ (Human molecular genetics 1999) 3 4 23 58
- Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M … Yamada Y (American journal of hypertension 2010) 3 45 58
ExternalLinks
Products for SIX5 Gene
- Custom Antibody ServicesOriGene Antibodies for SIX5
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- Custom Assay Services
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- Search Origene for MassSpec and Protein Over-expression Lysates for SIX5
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- Origene sirna, shrna, and RNAi products in human, mouse, rat for SIX5
- Browse OriGene Inhibitory RNA Products For SIX5
- OriGene qPCR primer pairs for SIX5
- OriGene CRISPR knockouts for SIX5
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SIX5
- Sino Biological Human cDNA Clone for SIX5
- Browse Sino Biological Recombinant Proteins
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- Browse Sino Biological Antibodies
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- Browse cDNA Clones
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SIX5
- Novus Biologicals proteins and lysates for SIX5
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SIX5
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SIX5 (AFLGC-SIX5)
- Cyagen custom Knockout/knockin (KOKI) mouse models for SIX5
- antibodies-online: Search results for available Six5 related products ranked by validation data
- antibodies-online: Search results for available Six5 related products ranked by validation data
- antibodies-online: Search results for available Six5 related products ranked by validation data
- Horizon Cell Lines for SIX5
- genomics-online: cdna clones - Search results for available Six5 gene related products
- orf clones - Search results for available Six5 gene related products
- genomics-online: gRNA clones - Search results for available Six5 gene related products
- genomics-online: primer clones - Search results for available Six5 gene related products
- genomics-online: shRNA clones - Search results for available Six5 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SIX5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SIX5
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SIX5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SIX5
- Boster Bio Antibodies for SIX5
- Browse Boster Bio ELISA Kits
Sources for SIX5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
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