Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SIX3-AS1 Gene

Subcategory (RNA class) for SIX3-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for SIX3-AS1 Gene

  • SIX3 Antisense RNA 1 2 3 5
  • SIX3 Antisense RNA 1 (Non-Protein Coding) 2 3
  • SIX3OS 3

External Ids for SIX3-AS1 Gene

Previous GeneCards Identifiers for SIX3-AS1 Gene

  • GC02M045169

Summaries for SIX3-AS1 Gene

GeneCards Summary for SIX3-AS1 Gene

SIX3-AS1 (SIX3 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for SIX3-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SIX3-AS1 Gene

Genomics for SIX3-AS1 Gene

GeneHancer (GH) Regulatory Elements for SIX3-AS1 Gene

Promoters and enhancers for SIX3-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I044941 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE 555.8 -1.3 -1349 3.7 PKNOX1 SUZ12 BACH1 SIN3A BMI1 RFX5 POLR2A ZNF143 PRDM10 ZNF444 SIX3-AS1 SIX3 ENSG00000225156
GH02I044943 Enhancer 0.5 ENCODE 550.8 +1.8 1792 0.8 SUZ12 CTBP2 ZNF398 EZH2 ENSG00000274547 ENSG00000276670 GC02P044942 LINC01833 SIX3 SIX3-AS1
GH02I044938 Enhancer 0.7 ENCODE 6.2 +3.2 3182 1.3 KLF1 SIN3A ZNF48 GLIS2 POLR2A PATZ1 PRDM10 RCOR1 ZNF600 CHD2 ENSG00000274547 ENSG00000276048 ENSG00000276670 GC02P044942 LINC01833 SIX3-AS1
GH02I044945 Enhancer 0.7 ENCODE 5.8 +4.0 4021 0.3 CTCF MAX SIN3A ELF1 REST GABPA SP1 ATF3 POLR2A CTBP2 ENSG00000274547 ENSG00000276048 LINC01833 SIX3-AS1
GH02I044951 Enhancer 0.7 Ensembl 0.4 -10.6 -10637 1.8 CTCF ZNF792 RB1 SUZ12 ARID4B BACH1 ZNF48 RAD21 ZNF335 ZNF143 SRBD1 ENSG00000225156 SIX3 SIX3-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SIX3-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SIX3-AS1 Gene

Genomic Locations for SIX3-AS1 Gene
chr2:44,940,154-44,941,878
(GRCh38/hg38)
Size:
1,725 bases
Orientation:
Minus strand
chr2:45,167,293-45,169,017
(GRCh37/hg19)

Genomic View for SIX3-AS1 Gene

Genes around SIX3-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SIX3-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SIX3-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SIX3-AS1 Gene

Proteins for SIX3-AS1 Gene

Post-translational modifications for SIX3-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SIX3-AS1 Gene

Domains & Families for SIX3-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SIX3-AS1 Gene

Function for SIX3-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SIX3-AS1 Gene

Localization for SIX3-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SIX3-AS1 Gene

Pathways & Interactions for SIX3-AS1 Gene

SuperPathways for SIX3-AS1 Gene

No Data Available

Interacting Proteins for SIX3-AS1 Gene

Gene Ontology (GO) - Biological Process for SIX3-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SIX3-AS1 Gene

Drugs & Compounds for SIX3-AS1 Gene

No Compound Related Data Available

Transcripts for SIX3-AS1 Gene

mRNA/cDNA for SIX3-AS1 Gene

(5) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SIX3-AS1 Gene

SIX3 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SIX3-AS1 Gene

No ASD Table

Relevant External Links for SIX3-AS1 Gene

GeneLoc Exon Structure for
SIX3-AS1
ECgene alternative splicing isoforms for
SIX3-AS1

Expression for SIX3-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SIX3-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for SIX3-AS1 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x13.5), Brain - Caudate (basal ganglia) (x10.7), Brain - Putamen (basal ganglia) (x8.9), and Pituitary (x8.2).

SOURCE GeneReport for Unigene cluster for SIX3-AS1 Gene:

Hs.503113
genes like me logo Genes that share expression patterns with SIX3-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SIX3-AS1 Gene

Orthologs for SIX3-AS1 Gene

Evolution for SIX3-AS1 Gene

ENSEMBL:
Gene Tree for SIX3-AS1 (if available)
TreeFam:
Gene Tree for SIX3-AS1 (if available)

No data available for Orthologs for SIX3-AS1 Gene

Paralogs for SIX3-AS1 Gene

No data available for Paralogs for SIX3-AS1 Gene

Variants for SIX3-AS1 Gene

Sequence variations from dbSNP and Humsavar for SIX3-AS1 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs116680477 conflicting-interpretations-of-pathogenicity, benign, not specified, Holoprosencephaly 2 44,942,629(-) G/A upstream_transcript_variant
rs121917878 pathogenic, Holoprosencephaly 2 44,942,780(-) C/G upstream_transcript_variant
rs121917879 pathogenic, Holoprosencephaly 2 44,942,874(-) G/C upstream_transcript_variant
rs121917880 pathogenic, Holoprosencephaly 2 44,942,853(-) T/C upstream_transcript_variant
rs121917881 pathogenic, Holoprosencephaly 2 44,942,310(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SIX3-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv457207 CNV loss 19166990
nsv526534 CNV loss 19592680
nsv581702 CNV loss 21841781
nsv953779 CNV deletion 24416366

Additional Variant Information for SIX3-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SIX3-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SIX3-AS1 Gene

Disorders for SIX3-AS1 Gene

Additional Disease Information for SIX3-AS1

No disorders were found for SIX3-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SIX3-AS1 Gene

Publications for SIX3-AS1 Gene

  1. Natural antisense transcripts associated with genes involved in eye development. (PMID: 15703187) Alfano G … Banfi S (Human molecular genetics 2005) 2 3 58
  2. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 58

Products for SIX3-AS1 Gene

Sources for SIX3-AS1 Gene

Content
Loading form....