Aliases for SIPA1L1 Gene
External Ids for SIPA1L1 Gene
Previous GeneCards Identifiers for SIPA1L1 Gene
GeneCards Summary for SIPA1L1 Gene
SIPA1L1 (Signal Induced Proliferation Associated 1 Like 1) is a Protein Coding gene. Diseases associated with SIPA1L1 include Colorectal Cancer, Hereditary Nonpolyposis, Type 7. Among its related pathways are Ras signaling pathway and Protein-protein interactions at synapses. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and ephrin receptor binding. An important paralog of this gene is SIPA1L2.
UniProtKB/Swiss-Prot Summary for SIPA1L1 Gene
Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity).