Aliases for SHISA7 Gene
External Ids for SHISA7 Gene
Previous GeneCards Identifiers for SHISA7 Gene
GeneCards Summary for SHISA7 Gene
SHISA7 (Shisa Family Member 7) is a Protein Coding gene. An important paralog of this gene is SHISA6.
UniProtKB/Swiss-Prot Summary for SHISA7 Gene
Transmembrane protein that regulates gamma-aminobutyric acid type A receptor (GABA(A)R) trafficking, channel deactivation kinetics and pharmacology, necessary for fast inhibitory transmission in the brain. Enhances the action of benzodiazepine, a primary GABA(A)Rs target drug, in the brain. May affect channel kinetics of AMPA-type glutamate receptors (AMPAR), the brain's main excitatory neurotransmitter, necessary for synaptic hippocampal plasticity, and memory recall. May regulate the induction and maintenance of long-term potentiation at Schaffer collaterals/CA3-CA1 excitatory synapses.