Aliases for SHISA5 Gene
External Ids for SHISA5 Gene
Previous GeneCards Identifiers for SHISA5 Gene
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. Related pseudogenes of this gene are found on chromosome X. [provided by RefSeq, Apr 2016]
GeneCards Summary for SHISA5 Gene
SHISA5 (Shisa Family Member 5) is a Protein Coding gene. Diseases associated with SHISA5 include Microcephaly 19, Primary, Autosomal Recessive and Microcephaly 15, Primary, Autosomal Recessive. Among its related pathways are DNA Damage Response. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and WW domain binding. An important paralog of this gene is UHRF1.
UniProtKB/Swiss-Prot Summary for SHISA5 Gene
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.