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Aliases for SH3TC1 Gene
Aliases for SH3TC1 Gene
External Ids for SH3TC1 Gene
- HGNC: 26009
- Entrez Gene: 54436
- Ensembl: ENSG00000125089
- UniProtKB: Q8TE82
Previous GeneCards Identifiers for SH3TC1 Gene
- GC04P008393
- GC04P008319
- GC04P008251
- GC04P008201
- GC04P008120
Summaries for SH3TC1 Gene
GeneCards Summary for SH3TC1 Gene
SH3TC1 (SH3 Domain And Tetratricopeptide Repeats 1) is a Protein Coding gene. An important paralog of this gene is SH3TC2.
Additional gene information for SH3TC1 Gene
- HGNC(26009)
- Entrez Gene(54436)
- Ensembl(ENSG00000125089)
- UniProtKB(Q8TE82)
- Open Targets Platform(ENSG00000125089)
- Search for SH3TC1 at DataMed
- Search for SH3TC1 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SH3TC1 Gene
Genomics for SH3TC1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SH3TC1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SH3TC1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SH3TC1
- Top Transcription factor binding sites by QIAGEN in the SH3TC1 gene promoter:
-
- Chx10
- E47
- Hand1
- Lmo2
- NF-kappaB
- NF-kappaB1
- NF-kappaB2
- Pax-6
- POU3F1
Genomic Locations for SH3TC1 Gene
Genomic Locations for SH3TC1 Gene
- chr4:8,182,072-8,241,803
- (GRCh38/hg38)
- Size:
- 59,732 bases
- Orientation:
- Plus strand
- chr4:8,183,799-8,243,530
- (GRCh37/hg19)
- Size:
- 59,732 bases
- Orientation:
- Plus strand
Genomic View for SH3TC1 Gene
Genes around SH3TC1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.1 by HGNC
- 4p16.1 by Entrez Gene
- 4p16.1 by Ensembl
SH3TC1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SH3TC1 Gene
Proteins for SH3TC1 Gene
-
Protein details for SH3TC1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TE82-S3TC1_HUMAN
- Recommended name:
- SH3 domain and tetratricopeptide repeat-containing protein 1
- Protein Accession:
- Q8TE82
- Q4W5G5
Protein attributes for SH3TC1 Gene
- Size:
- 1336 amino acids
- Molecular mass:
- 146961 Da
- Quaternary structure:
- No Data Available
Protein Expression for SH3TC1 Gene
Post-translational modifications for SH3TC1 Gene
Other Protein References for SH3TC1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ SH3TC1 Polyclonal Antibody and Immunotag™ SH3TC1 Antibody
-
Custom Antibody ServicesOriGene Antibodies for SH3TC1
- Novus Biologicals Antibodies for SH3TC1
- Invitrogen Antibodies for SH3TC1 (AFLGC-SH3TC1)
- antibodies-online: Show 11 available SH3TC1 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for SH3TC1
- Search Origene for MassSpec and Protein Over-expression Lysates for SH3TC1
- Origene Custom Protein Services for SH3TC1
No data available for DME Specific Peptides for SH3TC1 Gene
Domains & Families for SH3TC1 Gene
Gene Families for SH3TC1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for SH3TC1 Gene
- InterPro:
- Blocks:
-
- SH3 domain signature
- ProtoNet:
Suggested Antigen Peptide Sequences for SH3TC1 Gene
- GenScript: Design optimal peptide antigens:
-
- SH3TC1 protein (A2RRQ8_HUMAN)
- cDNA FLJ44177 fis, clone THYMU2037226, highly similar to SH3 domain and tetratricopeptide repeats-containing protein 1 (B3KWX8_HUMAN)
- SH3 domain and tetratricopeptide repeats 1, isoform CRA_b (D3DVT6_HUMAN)
- SH3 domain and tetratricopeptide repeats-containing protein 1 (S3TC1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SH3TC1 Gene
Function for SH3TC1 Gene
Phenotypes From GWAS Catalog for SH3TC1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | -- |
Phenotypes for SH3TC1 Gene
- MGI mutant phenotypes for SH3TC1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SH3TC1:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased viability
- Decreased shRNA abundance (Z-score < -2)
- Decreased viability in non-small-cell lung cancer (NSCLC) lineage
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
- Increased shRNA abundance (Z-score > 2)
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after direct virus infection
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after viral supernatant infection
Animal Models for SH3TC1 Gene
- MGI Knock Outs for SH3TC1:
-
- Sh3tc1 Sh3tc1<tm1b(EUCOMM)Hmgu>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SH3TC1 - Select products 50% OFF >
- * SH3TC1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SH3TC1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SH3TC1
-
Santa Cruz Biotechnology (SCBT) CRISPR for SH3TC1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SH3TC1
- Browse OriGene Inhibitory RNA Products For SH3TC1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SH3TC1
Clone Products
- Applied Biological Materials (abm): Clones for SH3TC1 - Select products 50% OFF >
- * SH3TC1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SH3TC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SH3TC1
Cell Line Products
-
Horizon Cell Lines for SH3TC1
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for SH3TC1 Gene
Localization for SH3TC1 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
| peroxisome | 0 |
- Cytosol (2)
- Nucleoli (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for SH3TC1 Gene
Pathways & Interactions for SH3TC1 Gene
Interacting Proteins for SH3TC1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for SH3TC1 Gene
Transcripts for SH3TC1 Gene
mRNA/cDNA for SH3TC1 Gene
- 2 REFSEQ mRNAs :
- 14 NCBI additional mRNA sequence :
- 25 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000245105 4303 nts (view in UCSC)
- ENST00000382521 829 nts (view in UCSC)
- ENST00000457650 617 nts (view in UCSC)
- ENST00000502350 2258 nts (view in UCSC)
- ENST00000502559 3798 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SH3TC1 - Select products 50% OFF >
- * SH3TC1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SH3TC1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SH3TC1
-
Santa Cruz Biotechnology (SCBT) CRISPR for SH3TC1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SH3TC1
- Browse OriGene Inhibitory RNA Products For SH3TC1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SH3TC1
Clone Products
- Applied Biological Materials (abm): Clones for SH3TC1 - Select products 50% OFF >
- * SH3TC1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SH3TC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SH3TC1
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | · | 13d | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP21: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP22: | - |
| ExUns: | 16b | ^ | 17a | · | 17b | · | 17c | · | 17d | ^ | 18 | ^ | 19a | · | 19b | · | 19c | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 | ^ | 23 | ^ | 24a | · | 24b | · | 24c | ^ | 25a | · | 25b | ^ | 26a | · | 26b | · | 26c | ^ | 27a | · | 27b | ^ | 28 | ^ | 29a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP19: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP21: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP22: |
Relevant External Links for SH3TC1 Gene
- GeneLoc Exon Structure for
- SH3TC1
Expression for SH3TC1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Endocardial Tube Cells Endocardium
-
Thymus (Hematopoietic System)
- Double Positive Thymocytes Thymus
-
Blood (Cardiovascular System)
- Double Positive Thymocytes Thymus
- Endothelium (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for SH3TC1 Gene
This gene is overexpressed in Whole Blood (x5.2) and Kidney - Cortex (x4.8).
This gene is overexpressed in Lung (19.0), Heart (18.4), Peripheral blood mononuclear cells (9.5), and Placenta (8.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SH3TC1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SH3TC1
SOURCE GeneReport for Unigene cluster for SH3TC1 Gene:
Hs.479116Primer Products
-
OriGene qPCR primer pairs for SH3TC1
Gene Expression Assay Products
No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SH3TC1 Gene
Orthologs for SH3TC1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SH3TC1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SH3TC1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SH3TC1 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Sh3tc1 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Sh3tc1 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | SH3TC1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SH3TC1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | SH3TC1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SH3TC1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | sh3tc1 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | sh3tc1 30 |
|
||
| SH3TC1 (1 of 2) 31 |
|
OneToMany | |||
| CR382383.3 31 |
|
OneToMany |
- Species where no ortholog for SH3TC1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SH3TC1 Gene
- ENSEMBL:
- Gene Tree for SH3TC1 (if available)
- TreeFam:
- Gene Tree for SH3TC1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SH3TC1: view image
Paralogs for SH3TC1 Gene
(2) SIMAP similar genes for SH3TC1 Gene using alignment to 14 proteins:
- S3TC1_HUMAN
- A2RRQ8_HUMAN
- B3KWX8_HUMAN
- D3DVT6_HUMAN
- D6RC98_HUMAN
- D6REB6_HUMAN
- D6RI07_HUMAN
- E7EQR1_HUMAN
- F5GXD3_HUMAN
- H0Y9A4_HUMAN
- H0YA34_HUMAN
- H0YAJ7_HUMAN
- Q6NVH2_HUMAN
- U3KQ04_HUMAN
Variants for SH3TC1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SH3TC1 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 708782 | Benign: not provided | 8,227,593(+) | G/A | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 775212 | Benign: not provided | 8,240,739(+) | A/. | NON_CODING_TRANSCRIPT_VARIANT,NO_SEQUENCE_ALTERATION | |
| 786034 | Benign: not provided | 8,217,135(+) | G/A | SYNONYMOUS_VARIANT | |
| rs1348201855 | A colorectal cancer sample | p.Ala1130Thr | |||
| rs201295499 | A colorectal cancer sample | p.Arg719His |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2729n106 | CNV | tandem duplication | 24896259 |
| dgv815e201 | CNV | deletion | 23290073 |
| dgv816e201 | CNV | deletion | 23290073 |
| esv2658523 | CNV | deletion | 23128226 |
| esv2763338 | CNV | gain | 21179565 |
| esv3363340 | CNV | duplication | 20981092 |
| esv34196 | OTHER | inversion | 12058347 |
| esv3563373 | CNV | deletion | 23714750 |
| esv3599542 | CNV | loss | 21293372 |
| esv3599543 | CNV | loss | 21293372 |
| nsv1002794 | CNV | gain | 25217958 |
| nsv1009011 | CNV | loss | 25217958 |
| nsv1136814 | CNV | deletion | 24896259 |
| nsv1161031 | CNV | deletion | 26073780 |
| nsv4220 | CNV | insertion | 18451855 |
| nsv461216 | CNV | loss | 19166990 |
| nsv470012 | CNV | loss | 18288195 |
| nsv593626 | CNV | loss | 21841781 |
| nsv593627 | CNV | gain | 21841781 |
| nsv829853 | CNV | gain+loss | 17160897 |
| nsv949784 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
99.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
13.13;
95.14% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SH3TC1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SH3TC1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SH3TC1 Gene
Disorders for SH3TC1 Gene
Additional Disease Information for SH3TC1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for SH3TC1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SH3TC1 Gene
Publications for SH3TC1 Gene
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G … Wijmenga C (Gut 2009) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. (PMID: 28611215) Fei T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2017) 3
- Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X … Chen J (Molecular systems biology 2015) 3
ExternalLinks
Products for SH3TC1 Gene
- Custom Antibody ServicesOriGene Antibodies for SH3TC1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SH3TC1
- Search Origene for MassSpec and Protein Over-expression Lysates for SH3TC1
- Origene Custom Protein Services for SH3TC1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SH3TC1
- Browse OriGene Inhibitory RNA Products For SH3TC1
- OriGene qPCR primer pairs for SH3TC1
- OriGene CRISPR knockouts for SH3TC1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SH3TC1
- Sino Biological Human cDNA Clone for SH3TC1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SH3TC1
- Novus Biologicals proteins and lysates for SH3TC1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for SH3TC1 (AFLGC-SH3TC1)
- VectorBuilder Custom and pre-made DNA vectors for SH3TC1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SH3TC1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SH3TC1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SH3TC1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SH3TC1
- antibodies-online: Show 11 available SH3TC1 Antibodies ranked by validation data
- antibodies-online: Search results for available SH3TC1 related products ranked by validation data
- antibodies-online: Search results for available SH3TC1 related products ranked by validation data
- Horizon Cell Lines for SH3TC1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SH3TC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SH3TC1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SH3TC1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SH3TC1
Sources for SH3TC1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB