Aliases for SH3BP5 Gene
External Ids for SH3BP5 Gene
Previous GeneCards Identifiers for SH3BP5 Gene
GeneCards Summary for SH3BP5 Gene
SH3BP5 (SH3 Domain Binding Protein 5) is a Protein Coding gene. Diseases associated with SH3BP5 include Endocardium Disease and Tabes Dorsalis. Among its related pathways are B cell receptor signaling pathway (KEGG). Gene Ontology (GO) annotations related to this gene include SH3 domain binding and protein kinase inhibitor activity. An important paralog of this gene is SH3BP5L.
UniProtKB/Swiss-Prot for SH3BP5 Gene
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.