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SH3BGR (SH3 Domain Binding Glutamate Rich Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include SH3 domain binding and SH3/SH2 adaptor activity. An important paralog of this gene is GET1-SH3BGR.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005070 | SH3/SH2 adaptor activity | TAS | -- |
GO:0017124 | SH3 domain binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005829 | cytosol | HDA | 16780588 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0009967 | positive regulation of signal transduction | IEA | -- |
GO:0065003 | protein-containing complex assembly | TAS | 9050928 |
ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||||||
SP2: | - | ||||||||||||||||
SP3: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SH3BGR 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | SH3BGR 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Sh3bgr 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | SH3BGR 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | SH3BGR 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
ManyToMany | |
Chicken (Gallus gallus) |
Aves | SH3BGR 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | SH3BGR 31 |
|
OneToOne | |
African clawed frog (Xenopus laevis) |
Amphibia | Xl.24537 30 |
|
||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | MGC75687 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | sh3bgr 31 |
|
OneToOne | |
Dr.13487 30 |
|
||||
Fruit Fly (Drosophila melanogaster) |
Insecta | Sh3beta 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | Y105E8A.1 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 21 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs11575939 | - | p.Asp23Glu | |||
rs6517549 | - | p.Asp50Asn | |||
rs9974333 | - | p.Val188Ala |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2723434 | CNV | deletion | 23290073 |
esv2758820 | CNV | gain | 17122850 |
esv34779 | CNV | gain | 17911159 |
esv3557717 | CNV | deletion | 23714750 |
nsv1061454 | CNV | gain | 25217958 |
nsv1067330 | CNV | loss | 25217958 |
nsv1126006 | CNV | deletion | 24896259 |
nsv964496 | CNV | duplication | 23825009 |
No disorders were found for SH3BGR Gene.