Aliases for SGCB Gene
External Ids for SGCB Gene
Previous HGNC Symbols for SGCB Gene
Previous GeneCards Identifiers for SGCB Gene
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008]
GeneCards Summary for SGCB Gene
SGCB (Sarcoglycan Beta) is a Protein Coding gene. Diseases associated with SGCB include Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 4 and Qualitative Or Quantitative Defects Of Beta-Sarcoglycan. Among its related pathways are Dilated cardiomyopathy (DCM) and Arrhythmogenic right ventricular cardiomyopathy (ARVC).
UniProtKB/Swiss-Prot Summary for SGCB Gene
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.