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This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protei... See more...
Aliases for SF1 Gene
Aliases for SF1 Gene
External Ids for SF1 Gene
- HGNC: 12950
- NCBI Entrez Gene: 7536
- Ensembl: ENSG00000168066
- OMIM®: 601516
- UniProtKB/Swiss-Prot: Q15637
Previous HGNC Symbols for SF1 Gene
- ZNF162
Previous GeneCards Identifiers for SF1 Gene
- GC11M067047
- GC11M066213
- GC11M064782
- GC11M064307
- GC11M064290
- GC11M064532
- GC11M060858
Summaries for SF1 Gene
-
This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
GeneCards Summary for SF1 Gene
SF1 (Splicing Factor 1) is a Protein Coding gene. Diseases associated with SF1 include Multiple Endocrine Neoplasia, Type I. Among its related pathways are mRNA Splicing - Major Pathway and Oct4 in Mammalian ESC Pluripotency. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is QKI.
UniProtKB/Swiss-Prot Summary for SF1 Gene
-
Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.
Additional gene information for SF1 Gene
- HGNC (12950)
- NCBI Entrez Gene (7536)
- Ensembl (ENSG00000168066)
- OMIM® (601516)
- UniProtKB/Swiss-Prot (Q15637)
- Open Targets Platform(ENSG00000168066)
- Search for SF1 at DataMed
- Search for SF1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SF1 Gene
Genomics for SF1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SF1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SF1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SF1
- Top Transcription factor binding sites by QIAGEN in the SF1 gene promoter:
-
- AREB6
- GATA-1
- Ik-2
- NF-1
- NF-kappaB1
- RFX1
- Sox9
Genomic Locations for SF1 Gene
Latest Assembly
- chr11:64,764,606-64,778,786
- (GRCh38/hg38)
- Size:
- 14,181 bases
- Orientation:
- Minus strand
Previous Assembly
- chr11:64,532,078-64,546,014
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 13,937 bases
- Orientation:
- Minus strand
- chr11:64,532,078-64,546,258
- (GRCh37/hg19 by Ensembl)
- Size:
- 14,181 bases
- Orientation:
- Minus strand
Genomic View for SF1 Gene
Genes around SF1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.1 by HGNC
- 11q13.1 by Entrez Gene
- 11q13.1 by Ensembl
SF1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SF1 Gene
Proteins for SF1 Gene
-
Protein details for SF1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q15637-SF01_HUMAN
- Recommended name:
- Splicing factor 1
- Protein Accession:
- Q15637
- B7Z1Q1
- C9JJE2
- Q14818
- Q14819
- Q15913
- Q8IY00
- Q92744
- Q92745
- Q969H7
- Q9BW01
- Q9UEI0
Protein attributes for SF1 Gene
- Size:
- 639 amino acids
- Molecular mass:
- 68330 Da
- Quaternary structure:
-
- Binds U2AF2. Interacts with U1 snRNA. Binds EWSR1, FUS and TAF15. Interacts with RBM17.
- SequenceCaution:
-
- Sequence=AAH00773.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for SF1 Gene
Protein Expression for SF1 Gene
Post-translational modifications for SF1 Gene
- Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463.
-
Ubiquitination at Lys227
- NX_Q15637 (NX_Q15637-1)
- Modification sites at PhosphoSitePlus
Other Protein References for SF1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_011543547.1
- XP_011543548.1
- XP_011543549.1
- XP_011543550.1
- XP_016873734.1
- XP_016873735.1
- XP_016873738.1
- XP_016873739.1
- XP_016873740.1
- XP_024304447.1
- XP_024304448.1
- NP_001171501.1
- NP_001171502.1
- NP_001333292.1
- NP_001333293.1
- NP_001333338.1
- NP_001333339.1
- NP_001365885.1
- NP_001365886.1
- NP_004621.2
- NP_973724.1
- NP_973726.2
- NP_973727.1
Antibodies for research
- NSJ Bioreagents SF1 Antibody / Splicing factor 1
- Novus Biologicals Antibodies for SF1
-
Abcam antibodies for SF1
- Invitrogen Antibodies for SF1 (AFLGC-SF1)
- antibodies-online: Show 182 available Splicing Factor 1 Antibodies ranked by validation data
- Compare Top Splicing Factor 1 Antibodies
-
Recommended
- 104 WB Antibodies (anti-human)
- 1 IHC Antibody (anti-human)
- 1 IHC (p) Antibody (anti-human)
- 1 IP Antibody (anti-human)
- 55 WB Antibodies (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- 1 IHC (p) Antibody (anti-mouse)
- 1 IP Antibody (anti-mouse)
- 29 WB Antibodies (anti-rat)
- 1 IHC Antibody (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
- 1 IP Antibody (anti-rat)
-
Santa Cruz Biotechnology (SCBT) Antibodies for SF1
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for SF1
- Origene Custom Protein Services for SF1
-
Abcam proteins for SF1
Assay products for research
- antibodies-online: Show 8 available Splicing Factor 1 Elisa Kits ranked by validation data
- Compare Top Splicing Factor 1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SF1 Gene
Domains & Families for SF1 Gene
Gene Families for SF1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for SF1 Gene
- InterPro:
- Blocks:
-
- C2HC-type zinc-finger signature
- KH domain
- KH, type 1
- ProtoNet:
Suggested Antigen Peptide Sequences for SF1 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ54064, highly similar to Splicing factor 1 (B4DX42_HUMAN)
- ZFM1 protein, alternatively spliced product (Q14820_HUMAN)
- Zinc finger protein 162 (SF01_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q15637- Family:
-
- Belongs to the BBP/SF1 family.
Function for SF1 Gene
Molecular function for SF1 Gene
- UniProtKB/Swiss-Prot Function:
- Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.
Phenotypes From GWAS Catalog for SF1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003714 | transcription corepressor activity | TAS | 9660765 |
| GO:0003723 | RNA binding | IEA,TAS | 8752089 |
| GO:0003729 | mRNA binding | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 10449420 |
Phenotypes for SF1 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SF1 - Starting at $85 >
- * SF1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SF1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SF1
-
Santa Cruz Biotechnology (SCBT) CRISPR for SF1
miRNA for SF1 Gene
- miRTarBase miRNAs that target SF1
-
- hsa-miR-186-5p (MIRT021119)
- hsa-miR-935 (MIRT036661)
- hsa-miR-320a (MIRT044484)
- hsa-miR-221-3p (MIRT046884)
- mmu-miR-320-3p (MIRT054740)
- hsa-miR-544a (MIRT246745)
- hsa-miR-6738-3p (MIRT246751)
- hsa-miR-513a-3p (MIRT267764)
- hsa-miR-513c-3p (MIRT267766)
- hsa-miR-3606-3p (MIRT267768)
- hsa-miR-3158-5p (MIRT333872)
- hsa-miR-6859-3p (MIRT442735)
- hsa-miR-4258 (MIRT442736)
- hsa-miR-489-3p (MIRT497360)
- hsa-miR-548as-3p (MIRT497361)
- hsa-miR-548z (MIRT497362)
- hsa-miR-548h-3p (MIRT497363)
- hsa-miR-548d-3p (MIRT497364)
- hsa-miR-548bb-3p (MIRT497365)
- hsa-miR-548ac (MIRT497366)
- hsa-miR-4294 (MIRT560264)
- hsa-miR-6124 (MIRT560265)
- hsa-miR-548ax (MIRT560266)
- hsa-miR-548ao-5p (MIRT560267)
- hsa-miR-3185 (MIRT560268)
- hsa-miR-802 (MIRT560269)
- hsa-miR-577 (MIRT560270)
- hsa-miR-651-3p (MIRT560271)
- hsa-miR-7-2-3p (MIRT560272)
- hsa-miR-7-1-3p (MIRT560273)
- hsa-miR-5688 (MIRT560274)
- hsa-miR-495-3p (MIRT560275)
- hsa-miR-3133 (MIRT560276)
- hsa-miR-539-5p (MIRT571648)
- hsa-miR-17-3p (MIRT571649)
- hsa-miR-1205 (MIRT571650)
- hsa-miR-1184 (MIRT571651)
- hsa-miR-3919 (MIRT571652)
- hsa-miR-3591-3p (MIRT571653)
- hsa-miR-21-3p (MIRT571654)
- hsa-miR-1262 (MIRT736677)
- hsa-miR-185-5p (MIRT738265)
- hsa-miR-3150b-3p (MIRT740332)
- hsa-miR-329-3p (MIRT741312)
- hsa-miR-362-3p (MIRT741784)
- hsa-miR-371a-5p (MIRT742591)
- hsa-miR-3941 (MIRT743149)
- hsa-miR-4259 (MIRT743460)
- hsa-miR-4283 (MIRT743721)
- hsa-miR-4306 (MIRT743922)
- hsa-miR-4428 (MIRT744313)
- hsa-miR-4437 (MIRT744499)
- hsa-miR-4644 (MIRT746394)
- hsa-miR-4689 (MIRT747043)
- hsa-miR-4701-3p (MIRT747301)
- hsa-miR-4710 (MIRT747428)
- hsa-miR-4784 (MIRT748849)
- hsa-miR-5195-5p (MIRT750001)
- hsa-miR-571 (MIRT751408)
- hsa-miR-603 (MIRT751634)
- hsa-miR-6085 (MIRT751810)
- hsa-miR-6129 (MIRT752190)
- hsa-miR-6715a-3p (MIRT753678)
- hsa-miR-6715b-3p (MIRT753683)
- hsa-miR-6736-5p (MIRT754220)
- hsa-miR-6741-5p (MIRT754347)
- hsa-miR-6771-3p (MIRT755307)
- hsa-miR-6813-5p (MIRT756746)
- hsa-miR-6858-5p (MIRT757801)
- hsa-miR-8485 (MIRT760288)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SF1
- Browse OriGene Inhibitory RNA Products For SF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SF1
Clone products for research
- Applied Biological Materials (abm): Clones for SF1 - Starting at $45 >
- * SF1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG225534
- MG225537
- MR225534
- MR225534L3
- MR225534L4
- MR225537
- MR225537L3
- MR225537L4
- RC205846
- RC205846L3
- RC205846L4
- RC219995
- RC219995L3
- RC219995L4
- RC220045
- RC220045L3
- RC220045L4
- RC223837
- RC223837L3
- RC223837L4
- RC230349
- RC230349L3
- RC230349L4
- RC230417
- RC230417L3
- RC230417L4
- RG205846
- RG219995
- RG220045
- RG223837
- RG230349
- RG230417
- RR200215
- RR200215L3
- RR200215L4
- RR200216
- RR200216L3
- RR200216L4
- MR225534L3V
- MR225534L4V
- MR225537L3V
- MR225537L4V
- RC205846L3V
- RC205846L4V
- RC219995L3V
- RC219995L4V
- RC220045L3V
- RC220045L4V
- RC223837L3V
- RC223837L4V
- RC230349L3V
- RC230349L4V
- RC230417L3V
- RC230417L4V
- RR200215L3V
- RR200215L4V
- RR200216L3V
- RR200216L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for SF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SF1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SF1 Gene
Localization for SF1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SF1 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA,NAS | 7912130 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005681 | spliceosomal complex | IDA | 9731529 |
| GO:0005840 | ribosome | NAS | 8752089 |
| GO:0016604 | nuclear body | IDA | -- |
Pathways & Interactions for SF1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.79
|
|
| 2 | Oct4 in Mammalian ESC Pluripotency |
Oct4 in Mammalian ESC Pluripotency
-
|
|
| 3 | Gene Expression |
.48
|
|
Pathways by source for SF1 Gene
4 Reactome pathways for SF1 Gene
1 Qiagen pathway for SF1 Gene
- Oct4 in Mammalian ESC Pluripotency
Interacting Proteins for SF1 Gene
Selected Interacting proteins:
Q15637-SF01_HUMAN
ENSP00000366604
for SF1 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for SF1
SIGNOR curated interactions for SF1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000245 | spliceosomal complex assembly | NAS | 8752089 |
| GO:0000381 | regulation of alternative mRNA splicing, via spliceosome | IBA | -- |
| GO:0000389 | mRNA 3'-splice site recognition | TAS | 15647371 |
| GO:0000398 | mRNA splicing, via spliceosome | IEA,TAS | -- |
| GO:0006397 | mRNA processing | IEA | -- |
Drugs & Compounds for SF1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Dihydroartemisinin | Experimental, Investigational | Pharma | Target, ligand | 119 |
Transcripts for SF1 Gene
mRNA/cDNA for SF1 Gene
- 12 REFSEQ mRNAs :
- 29 NCBI additional mRNA sequence :
- 21 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000227503 2850 nts (view in UCSC)
- ENST00000334944 3094 nts (view in UCSC)
- ENST00000377387 2947 nts (view in UCSC)
- ENST00000377390 3282 nts (view in UCSC)
- ENST00000377394 2854 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for SF1 - Starting at $85 >
- * SF1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for SF1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SF1
-
Santa Cruz Biotechnology (SCBT) CRISPR for SF1
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SF1
- Browse OriGene Inhibitory RNA Products For SF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SF1
Clone products for research
- Applied Biological Materials (abm): Clones for SF1 - Starting at $45 >
- * SF1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG225534
- MG225537
- MR225534
- MR225534L3
- MR225534L4
- MR225537
- MR225537L3
- MR225537L4
- RC205846
- RC205846L3
- RC205846L4
- RC219995
- RC219995L3
- RC219995L4
- RC220045
- RC220045L3
- RC220045L4
- RC223837
- RC223837L3
- RC223837L4
- RC230349
- RC230349L3
- RC230349L4
- RC230417
- RC230417L3
- RC230417L4
- RG205846
- RG219995
- RG220045
- RG223837
- RG230349
- RG230417
- RR200215
- RR200215L3
- RR200215L4
- RR200216
- RR200216L3
- RR200216L4
- MR225534L3V
- MR225534L4V
- MR225537L3V
- MR225537L4V
- RC205846L3V
- RC205846L4V
- RC219995L3V
- RC219995L4V
- RC220045L3V
- RC220045L4V
- RC223837L3V
- RC223837L4V
- RC230349L3V
- RC230349L4V
- RC230417L3V
- RC230417L4V
- RR200215L3V
- RR200215L4V
- RR200216L3V
- RR200216L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for SF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SF1
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: |
| ExUns: | 14 | ^ | 15a | · | 15b | · | 15c | · | 15d | ^ | 16a | · | 16b | ^ | 17a | · | 17b | ^ | 18a | · | 18b | · | 18c | ^ | 19 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||
| SP8: | - | ||||||||||||||||||||||||
| SP9: | - | ||||||||||||||||||||||||
| SP10: | - | - | |||||||||||||||||||||||
| SP11: | - | ||||||||||||||||||||||||
| SP12: | |||||||||||||||||||||||||
| SP13: | |||||||||||||||||||||||||
| SP14: | - | - | |||||||||||||||||||||||
| SP15: | |||||||||||||||||||||||||
| SP16: | |||||||||||||||||||||||||
| SP17: | |||||||||||||||||||||||||
| SP18: | - | - | - | ||||||||||||||||||||||
| SP19: | |||||||||||||||||||||||||
| SP20: |
Relevant External Links for SF1 Gene
- GeneLoc Exon Structure for
- SF1
Expression for SF1 Gene
This gene is overexpressed in Lymph node (13.7) and NK cells (7.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SF1 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SF1
SOURCE GeneReport for Unigene cluster for SF1 Gene:
Hs.502829mRNA Expression by UniProt/SwissProt for SF1 Gene:
Q15637-SF01_HUMAN
Tissue specificity:
Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart.
Evidence on tissue expression from TISSUES for SF1 Gene
- Nervous system(4.9)
- Skin(4.6)
- Muscle(4.6)
- Kidney(4.6)
- Liver(4.5)
- Blood(4.5)
- Eye(4.4)
- Bone(4)
- Lung(3.5)
- Intestine(3)
- Lymph node(2.5)
- Heart(2.4)
- Thyroid gland(2.3)
- Bone marrow(2.3)
- Adrenal gland(2.3)
- Spleen(2.1)
- Pancreas(2.1)
Primer products for research
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OriGene qPCR primer pairs for SF1
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OriGene qPCR primer pairs and template standards for SF1
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SF1 Gene
Orthologs for SF1 Gene
This gene was present in the common ancestor of animals and fungi.