Aliases for SERTAD2 Gene
External Ids for SERTAD2 Gene
Previous GeneCards Identifiers for SERTAD2 Gene
GeneCards Summary for SERTAD2 Gene
SERTAD2 (SERTA Domain Containing 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity. An important paralog of this gene is CDCA4.
UniProtKB/Swiss-Prot Summary for SERTAD2 Gene
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism.