Aliases for SERTAD2 Gene
External Ids for SERTAD2 Gene
Previous GeneCards Identifiers for SERTAD2 Gene
GeneCards Summary for SERTAD2 Gene
SERTAD2 (SERTA Domain Containing 2) is a Protein Coding gene. Diseases associated with SERTAD2 include Retinitis Pigmentosa 28. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity. An important paralog of this gene is CDCA4.
UniProtKB/Swiss-Prot Summary for SERTAD2 Gene
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism.