Aliases for SERPINB9 Gene
External Ids for SERPINB9 Gene
Previous HGNC Symbols for SERPINB9 Gene
Previous GeneCards Identifiers for SERPINB9 Gene
This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012]
GeneCards Summary for SERPINB9 Gene
SERPINB9 (Serpin Family B Member 9) is a Protein Coding gene. Diseases associated with SERPINB9 include Pituitary Adenoma 2, Growth Hormone-Secreting and Pituitary Adenoma 3, Multiple Types. Among its related pathways are Amoebiasis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity and cysteine-type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is SERPINB6.
UniProtKB/Swiss-Prot Summary for SERPINB9 Gene
Granzyme B inhibitor.