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This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] See more...
Aliases for SERPINB7 Gene
Aliases for SERPINB7 Gene
External Ids for SERPINB7 Gene
- HGNC: 13902
- Entrez Gene: 8710
- Ensembl: ENSG00000166396
- OMIM: 603357
- UniProtKB: O75635
Previous GeneCards Identifiers for SERPINB7 Gene
- GC18P061281
- GC18P061394
- GC18P059569
- GC18P059571
- GC18P058121
Summaries for SERPINB7 Gene
-
This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
GeneCards Summary for SERPINB7 Gene
SERPINB7 (Serpin Family B Member 7) is a Protein Coding gene. Diseases associated with SERPINB7 include Palmoplantar Keratoderma, Nagashima Type and Palmoplantar Keratosis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB3.
UniProtKB/Swiss-Prot Summary for SERPINB7 Gene
-
Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.
Additional gene information for SERPINB7 Gene
- Monarch Initiative
- Search for SERPINB7 at DataMed
- Search for SERPINB7 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SERPINB7 Gene
Genomics for SERPINB7 Gene
GeneHancer (GH) Regulatory Elements for SERPINB7 Gene
Promoters and enhancers for SERPINB7 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH18J063774 | Promoter/Enhancer | 1.5 | EPDnew Ensembl ENCODE dbSUPER | 511.7 | +24.7 | 24693 | 6.7 | JUND FOS FOSL2 CEBPB JUN EP300 RFX5 POLR2A TAF1 STAT3 | SERPINB7 SERPINB10 piR-32023-098 HSALNG0122068 | |
| GH18J063753 | Promoter | 0.3 | EPDnew | 500.7 | +0.1 | 103 | 0.1 | SERPINB7 piR-32023-098 | ||
| GH18J063680 | Enhancer | 1 | FANTOM5 ENCODE | 11.2 | -70.3 | -70281 | 3.4 | TCF12 NCOR1 TEAD4 POLR2A EP300 FOXA2 BRCA1 FOS FOSL2 CEBPB | SERPINB3 SERPINB7 SERPINB12 SERPINB11 SERPINB5 HSALNG0122064 | |
| GH18J063730 | Enhancer | 0.7 | Ensembl ENCODE | 12.1 | -21.8 | -21754 | 1.6 | USF1 MAFF MAFK CEBPB MAX TBP TCF7L2 USF2 ZBTB12 | SERPINB7 SERPINB5 SERPINB11 SERPINB10 lnc-SERPINB3-5 piR-50968-052 | |
| GH18J063588 | Enhancer | 0.5 | Ensembl | 9.6 | -162.8 | -162823 | 3 | CEBPB SPI1 POLR2A MYC MAX FOS STAT3 | SERPINB11 SERPINB12 SERPINB7 SERPINB10 SERPINB13 piR-38351-233 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SERPINB7 on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SERPINB7
- Top Transcription factor binding sites by QIAGEN in the SERPINB7 gene promoter:
-
- AP-1
- ATF-2
- c-Fos
- c-Jun
Genomic Locations for SERPINB7 Gene
Genomic Locations for SERPINB7 Gene
- chr18:63,752,935-63,805,376
- (GRCh38/hg38)
- Size:
- 52,442 bases
- Orientation:
- Plus strand
- chr18:61,420,169-61,472,604
- (GRCh37/hg19)
- Size:
- 52,436 bases
- Orientation:
- Plus strand
Genomic View for SERPINB7 Gene
Genes around SERPINB7 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18q21.33 by HGNC
- 18q21.33 by Entrez Gene
- 18q21.33 by Ensembl
SERPINB7 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SERPINB7 Gene
Proteins for SERPINB7 Gene
-
Protein details for SERPINB7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75635-SPB7_HUMAN
- Recommended name:
- Serpin B7
- Protein Accession:
- O75635
- B4DUW8
- F5GZC0
- Q1ED45
- Q3KPG4
Protein attributes for SERPINB7 Gene
- Size:
- 380 amino acids
- Molecular mass:
- 42905 Da
- Quaternary structure:
- No Data Available
Protein Expression for SERPINB7 Gene
Post-translational modifications for SERPINB7 Gene
Other Protein References for SERPINB7 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ SERPINB7 Antibody
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-
Custom Antibody ServicesOriGene Antibodies for SERPINB7
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-
Abcam antibodies for SERPINB7
- Invitrogen Antibodies for SERPINB7 (AFLGC-SERPINB7)
- antibodies-online: Show 17 available SERPINB7 Antibodies ranked by validation data
-
Santa Cruz Biotechnology (SCBT) Antibodies for SERPINB7
Protein Products
-
OriGene Purified Proteins for SERPINB7
- Search Origene for MassSpec and Protein Over-expression Lysates for SERPINB7
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-
Abcam proteins for SERPINB7
No data available for DME Specific Peptides for SERPINB7 Gene
Domains & Families for SERPINB7 Gene
Gene Families for SERPINB7 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
Protein Domains for SERPINB7 Gene
- Blocks:
-
- Serpin
- Maspin signature
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SERPINB7 Gene
- GenScript: Design optimal peptide antigens:
-
- TP55 (SPB7_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O75635- Family:
-
- Belongs to the serpin family. Ov-serpin subfamily.
Function for SERPINB7 Gene
Molecular function for SERPINB7 Gene
- UniProtKB/Swiss-Prot Function:
- Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.
Phenotypes From GWAS Catalog for SERPINB7 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004867 | serine-type endopeptidase inhibitor activity | IBA | 21873635 |
| GO:0030414 | peptidase inhibitor activity | IEA | -- |
Phenotypes for SERPINB7 Gene
- GenomeRNAi human phenotypes for SERPINB7:
-
- Increased homologous recombination repair frequency
- Decreased ionizing radiation sensitivity
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Decreased Dengue Infection
- Decreased infection with West Nile virus (WNV)
- Decreased West Nile virus (WNV) infection
- Decreased NF-kappaB reporter expression
- Increased viability
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
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-
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SERPINB7
- genomics-online: gRNA clones - Search for available SERPINB7 gRNA products
- Overview of 109 available SERPINB7 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SERPINB7
miRNA Products
Inhibitory RNA Products
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- Overview of 109 available SERPINB7 gene related products
Clone Products
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Cell Line Products
-
Horizon Cell Lines for SERPINB7
No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SERPINB7 Gene
Localization for SERPINB7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SERPINB7 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| cytosol | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| peroxisome | 0 |
- Endoplasmic reticulum (2)
- Mitochondria (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for SERPINB7 Gene
Interacting Proteins for SERPINB7 Gene
GPS-Prot Interaction Network for SERPINB7
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010466 | negative regulation of peptidase activity | IEA | -- |
| GO:0010951 | negative regulation of endopeptidase activity | IBA | 21873635 |
| GO:0032914 | positive regulation of transforming growth factor beta1 production | IEA | -- |
| GO:0032967 | positive regulation of collagen biosynthetic process | IEA | -- |
| GO:0072126 | positive regulation of glomerular mesangial cell proliferation | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for SERPINB7 Gene
Transcripts for SERPINB7 Gene
mRNA/cDNA for SERPINB7 Gene
- 4 REFSEQ mRNAs :
- 15 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000336429 1976 bps (ENST00000336429.6)
- ENST00000398019 2195 bps (ENST00000398019.7)
- ENST00000425392 587 bps (ENST00000425392.5)
- ENST00000431370 560 bps (ENST00000431370.1)
- ENST00000447428 561 bps (ENST00000447428.5)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SERPINB7 - Select products 50% OFF >
- * SERPINB7 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SERPINB7
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SERPINB7
- genomics-online: gRNA clones - Search for available SERPINB7 gRNA products
- Overview of 109 available SERPINB7 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SERPINB7
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SERPINB7
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SERPINB7
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- Overview of 109 available SERPINB7 gene related products
Clone Products
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- Sino Biological Human cDNA Clone for SERPINB7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SERPINB7
Relevant External Links for SERPINB7 Gene
- GeneLoc Exon Structure for
- SERPINB7
Expression for SERPINB7 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Epithelial Cells (Uncategorized)
- Eye (Sensory Organs)
- Mesenchymal Stem Cells (Uncategorized)
- Umbilical Cord (Extraembryonic Tissues)
- Dermis (Integumentary System)
- Fibroblasts
- Epidermis (Integumentary System)
- Hair
-
Tonsil (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for SERPINB7 Gene
This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x26.2) and Skin - Not Sun Exposed (Suprapubic) (x20.9).
This gene is overexpressed in Serum (56.4) and Islet of Langerhans (8.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SERPINB7 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SERPINB7
SOURCE GeneReport for Unigene cluster for SERPINB7 Gene:
Hs.138202mRNA Expression by UniProt/SwissProt for SERPINB7 Gene:
O75635-SPB7_HUMAN
Tissue specificity:
Predominantly expressed in mesangial cells. Expressed in the epidermis of the whole body.
Evidence on tissue expression from TISSUES for SERPINB7 Gene
- Kidney(4.4)
- Skin(2.3)
Phenotype-based relationships between genes and organs from Gene ORGANizer for SERPINB7 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- cardiovascular
- immune
- integumentary
- nervous
Regions:
Head and neck:
- brain
- head
Limb:
- foot
- hand
- lower limb
- upper limb
General:
- blood
- blood vessel
- skin
- sweat gland
Primer Products
-
OriGene qPCR primer pairs for SERPINB7
Gene Expression Assay Products
Orthologs for SERPINB7 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SERPINB7 31 30 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SERPINB7 31 30 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SERPINB7 31 30 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Serpinb7 17 31 30 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Serpinb7 30 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | SERPINB7 31 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | Spn1 31 |
|
ManyToMany | |
| Spn42De 31 |
|
ManyToMany | |||
| Spn6 31 |
|
ManyToMany | |||
| Spn5 32 |
|
|
|||
| Spn42Dc 31 |
|
ManyToMany | |||
| Spn3 31 |
|
ManyToMany | |||
| Spn2 31 |
|
ManyToMany | |||
| Spn7 31 |
|
ManyToMany | |||
| Spn43Aa 31 |
|
ManyToMany | |||
| Spn4 31 |
|
ManyToMany | |||
| Spn47C 31 |
|
ManyToMany | |||
| Spn42Db 31 |
|
ManyToMany | |||
| Spn28Da 31 |
|
ManyToMany | |||
| Spn28Db 31 |
|
ManyToMany | |||
| Spn43Ab 31 |
|
ManyToMany | |||
| nec 31 |
|
ManyToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | srp-6 32 |
|
|
|
| srp-7 32 |
|
|
|||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for SERPINB7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- zebrafish (Danio rerio)
Evolution for SERPINB7 Gene
- ENSEMBL:
- Gene Tree for SERPINB7 (if available)
- TreeFam:
- Gene Tree for SERPINB7 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SERPINB7: view image
Paralogs for SERPINB7 Gene
Paralogs for SERPINB7 Gene
- SERPINB3 5
- SERPINB12 5
- SERPINB4 5
- SERPINB13 5
- SERPINB1 5
- SERPINB6 5
- SERPINB2 5
- SERPINB8 5
- SERPINB9 5
- SERPINB10 5
- SERPINB11 5
- SERPINC1 5
- SERPINB5 5
- SERPINA3 5
- SERPINA9 5
- SERPINA4 5
- SERPINI1 5
- SERPINI2 5
- SERPINA10 5
- SERPINA5 5
- SERPINA7 5
- SERPINE1 5
- SERPINA1 5
- SERPINA12 5
- SERPINA11 5
- SERPIND1 5
- SERPINF2 5
- SERPINE2 5
- SERPINE3 5
- SERPINA6 5
- SERPINH1 5
- SERPINF1 5
- SERPING1 5
- AGT 5
- SERPINA2 5
- HMSD 5
(28) SIMAP similar genes for SERPINB7 Gene using alignment to 3 proteins:
- SPB7_HUMAN
- C9JA68_HUMAN
- C9JM00_HUMAN
Variants for SERPINB7 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SERPINB7 Gene
| SNP ID | Clinical significance and condition | Chr 18 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 808403 | Uncertain Significance: not provided | 63,804,628(+) | G/A | MISSENSE_VARIANT | |
| rs142859678 | Pathogenic: Palmoplantar keratoderma, nagashima type; not provided | 63,804,288(+) | C/T | NONSENSE | |
| rs577442939 | Pathogenic: Palmoplantar keratoderma, nagashima type | 63,798,603(+) | G/A | SPLICE_ACCEPTOR_VARIANT | |
| rs672601344 | Pathogenic: Palmoplantar keratoderma, nagashima type; not provided | 63,798,670(+) | C/CT | FRAMESHIFT_VARIANT | |
| rs797044479 | Pathogenic: Palmoplantar keratoderma, nagashima type | 63,792,442(+) | AG/TAAACTTTACCT | FRAMESHIFT_VARIANT,INTRON_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1109412 | CNV | insertion | 17803354 |
| esv21739 | CNV | gain | 19812545 |
| esv3642781 | CNV | gain | 21293372 |
| esv3893113 | CNV | gain | 25118596 |
| nsv1066552 | CNV | gain | 25217958 |
| nsv1138635 | CNV | deletion | 24896259 |
| nsv833672 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
47.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.14;
80.68% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SERPINB7 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SERPINB7 Gene
Disorders for SERPINB7 Gene
(13) MalaCards diseases for SERPINB7 Gene - From: OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| palmoplantar keratoderma, nagashima type |
|
|
| palmoplantar keratosis |
|
|
| keratosis |
|
|
| serpinopathy |
|
|
| iga nephropathy 1 |
|
Search SERPINB7 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
SPB7_HUMAN- Keratoderma, palmoplantar, Nagashima type (PPKN) [MIM:615598]: An autosomal recessive, non-syndromic, diffuse palmoplantar keratosis characterized by well-demarcated diffuse erythematous hyperkeratosis expanding onto the dorsal surfaces of the palms and feet and the Achilles tendon area. Hyperkeratosis is mild and non-progressive. {ECO:0000269 PubMed:24207119}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for SERPINB7
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for SERPINB7 Gene
Publications for SERPINB7 Gene
- Megsin 2093T-2180C haplotype at the 3' untranslated region is associated with poor renal survival in Korean IgA nephropathy patients. (PMID: 18793525) Lim CS … Kim S (Clinical nephrology 2008) 3 23 41 54
- [Correlation between traditional Chinese medicine syndromes in primary immunoglobulin A nephropathy and A267G in 5'-untranslated region within exonal of megsin gene]. (PMID: 18471408) Zhong YF … Wang ZH (Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 2008) 3 23 41 54
- The influence of two megsin polymorphisms on the progression of IgA nephropathy. (PMID: 18498720) Maixnerová D … Tesar V (Folia biologica 2008) 3 23 41 54
- [Association of single nucleotide polymorphism of megsin gene with IgA nephropathy]. (PMID: 16796905) Wang ZH … Han B (Zhonghua yi xue za zhi 2006) 3 23 41 54
- Association of MEGSIN 2093C-2180T haplotype at the 3' untranslated region with disease severity and progression of IgA nephropathy. (PMID: 16431886) Xia Y … Wang Y (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006) 3 23 41 54
ExternalLinks
Products for SERPINB7 Gene
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- VectorBuilder Viral vectors for SERPINB7 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SERPINB7 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SERPINB7 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SERPINB7
- antibodies-online: Show 17 available SERPINB7 Antibodies ranked by validation data
- antibodies-online: Search results for available SERPINB7 related products ranked by validation data
- antibodies-online: Search results for available SERPINB7 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for SERPINB7
- Search Santa Cruz Biotechnology (SCBT) for SERPINB7 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SERPINB7
- Horizon Cell Lines for SERPINB7
- genomics-online: cdna clones - Search for available SERPINB7 CDNA products
- Overview of 109 available SERPINB7 gene related products
- orf clones - Search for available SERPINB7 ORF products
- Overview of 109 available SERPINB7 gene related products
- genomics-online: gRNA clones - Search for available SERPINB7 gRNA products
- Overview of 109 available SERPINB7 gene related products
- genomics-online: primer clones - Search for available SERPINB7 Primer products
- Overview of 109 available SERPINB7 gene related products
- genomics-online: shRNA clones - Search for available SERPINB7 shRNA products
- Overview of 109 available SERPINB7 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SERPINB7
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SERPINB7
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SERPINB7
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SERPINB7
Sources for SERPINB7 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
- (57) Tocris
- (58) Abcam
- (59) Novus Biologicals
- (60) ProSpec
- (61) Sino Biological
- (62) GenScript
- (63) Qiagen
- (64) OCA
- (65) Proteopedia
- (66) MOPED
- (67) neXtProt
- (68) Reactome
- (69) GeneGo (Thomson Reuters)
- (70) DISEASES
- (71) SIMAP
- (72) GenomeRNAi
- (73) LifeMap
- (74) miRTarBase
- (75) MalaCards
- (76) Invitrogen
- (77) BitterDB
- (78) ESI-BIO
- (79) RefSeq
- (80) BioSystems
- (81) MaxQB
- (82) IUPHAR
- (83) BioGPS
- (84) Illumina
- (85) COMPARTMENTS
- (86) HOMER
- (87) PaxDb
- (88) ApexBio
- (89) Addgene
- (90) antibodies-online
- (91) CYP
- (92) NONCODE
- (93) TreeFam
- (94) PathCards
- (95) GeneReviews
- (96) GeneTex
- (97) Taconic Biosciences
- (98) GTEx
- (99) ProteomicsDB
- (100) SCBT
- (101) DGIdb
- (102) ClinicalTrials
- (103) RVIS
- (104) SIGNOR
- (105) diseasecard
- (106) NIH Rare Diseases
- (107) Orphanet
- (108) UMLS
- (109) GTR
- (110) Disease Ontology
- (111) Genetics Home Reference
- (112) MeSH
- (113) MedlinePlus
- (114) CDC
- (115) NINDS
- (116) NCBI Bookshelf
- (117) ClinVar
- (118) Gene Damage Index
- (119) HPO
- (120) UDN
- (121) VISTA
- (122) FANTOM5
- (123) ENCODE
- (124) ProSci
- (125) Horizon
- (126) The Signaling Pathways Project (SPP)
- (127) IID
- (128) VectorBuilder
- (129) SNPedia
- (130) BRCA Exchange
- (131) CIViC
- (132) ProteoGenix
- (133) dbSUPER
- (134) TISSUES
- (135) Gene ORGANizer
- (136) abm
- (137) Human Protein Atlas
- (138) GWAS Catalog
- (139) Monarch Initiative
- (140) DataMed
- (141) HumanCyc
- (142) genomics-online
- (143) UCNEbase
- (144) EPDnew
- (145) Applied Biosystems
- (146) GlyConnect
- (147) Aminode
- (148) GeneCopoeia
- (149) GPS-Prot
- (150) RNACentral
- (151) LncRNADisease
- (152) LOVD
- (153) miR2Disease
- (154) DiseaseEnhancer
- (155) Boster Bio
- (156) Biorbyt
- (157) Biocompare
- (158) Mastermind
- (159) CTD^2 Dashboard
- (160) CraniofacialAtlas
- (161) GeneImprint
- (162) Synthego
- (163) Bio Basic
- (164) ENA
- (165) GtRNAdb
- (166) LncBase
- (167) LncBook
- (168) LNCipedia
- (169) LncRNAdb
- (170) Modomics
- (171) PDBe
- (172) Rfam
- (173) SILVA
- (174) snOPY
- (175) SRPDB
- (176) GENCODE
- (177) TarBase
- (178) MyBioSource
- (179) Signalway Antibody