Aliases for SERPINB5 Gene
External Ids for SERPINB5 Gene
Previous HGNC Symbols for SERPINB5 Gene
Previous GeneCards Identifiers for SERPINB5 Gene
GeneCards Summary for SERPINB5 Gene
SERPINB5 (Serpin Family B Member 5) is a Protein Coding gene. Diseases associated with SERPINB5 include Pleomorphic Adenoma and Syringoma. Among its related pathways are Direct p53 effectors and DNA Damage Response. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB1.
UniProtKB/Swiss-Prot Summary for SERPINB5 Gene
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.