Aliases for SERPINB3 Gene
External Ids for SERPINB3 Gene
Previous HGNC Symbols for SERPINB3 Gene
Previous GeneCards Identifiers for SERPINB3 Gene
GeneCards Summary for SERPINB3 Gene
SERPINB3 (Serpin Family B Member 3) is a Protein Coding gene. Diseases associated with SERPINB3 include Lung Cancer and Cervical Squamous Cell Carcinoma. Among its related pathways are Innate Immune System and Amoebiasis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB4.
UniProtKB/Swiss-Prot Summary for SERPINB3 Gene
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).