Aliases for SERPINB13 Gene
External Ids for SERPINB13 Gene
Previous HGNC Symbols for SERPINB13 Gene
Previous GeneCards Identifiers for SERPINB13 Gene
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein inhibits the activity of cathepsin K and is itself transcriptionally repressed by RUNX1. This gene is downregulated in many types of cancer. [provided by RefSeq, Jan 2017]
GeneCards Summary for SERPINB13 Gene
SERPINB13 (Serpin Family B Member 13) is a Protein Coding gene. Diseases associated with SERPINB13 include Cardiomyopathy, Dilated, 1O and Psoriasis. Among its related pathways are Amoebiasis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB3.
UniProtKB/Swiss-Prot Summary for SERPINB13 Gene
May play a role in the proliferation or differentiation of keratinocytes.