Aliases for SERPINB10 Gene
External Ids for SERPINB10 Gene
Previous HGNC Symbols for SERPINB10 Gene
Previous GeneCards Identifiers for SERPINB10 Gene
This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer. [provided by RefSeq, Dec 2015]
GeneCards Summary for SERPINB10 Gene
SERPINB10 (Serpin Family B Member 10) is a Protein Coding gene. Diseases associated with SERPINB10 include Chronic Myelomonocytic Leukemia and Cardiomyopathy, Familial Hypertrophic, 1. Among its related pathways are Innate Immune System and Amoebiasis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB2.
UniProtKB/Swiss-Prot Summary for SERPINB10 Gene
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.