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This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer. [provided by RefSeq, Dec 2015] See more...
Aliases for SERPINB10 Gene
Aliases for SERPINB10 Gene
External Ids for SERPINB10 Gene
- HGNC: 8942
- Entrez Gene: 5273
- Ensembl: ENSG00000242550
- OMIM: 602058
- UniProtKB: P48595
Previous HGNC Symbols for SERPINB10 Gene
- PI10
Previous GeneCards Identifiers for SERPINB10 Gene
- GC18P061421
- GC18P061556
- GC18P061367
- GC18P059731
- GC18P059733
- GC18P058283
Summaries for SERPINB10 Gene
-
This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer. [provided by RefSeq, Dec 2015]
GeneCards Summary for SERPINB10 Gene
SERPINB10 (Serpin Family B Member 10) is a Protein Coding gene. Diseases associated with SERPINB10 include Chronic Myelomonocytic Leukemia and Cardiomyopathy, Familial Hypertrophic, 1. Among its related pathways are Innate Immune System and Amoebiasis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB2.
UniProtKB/Swiss-Prot Summary for SERPINB10 Gene
-
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.
Additional gene information for SERPINB10 Gene
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SERPINB10 Gene
Genomics for SERPINB10 Gene
GeneHancer (GH) Regulatory Elements for SERPINB10 Gene
Promoters and enhancers for SERPINB10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SERPINB10 on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SERPINB10
- Top Transcription factor binding sites by QIAGEN in the SERPINB10 gene promoter:
-
- AREB6
- Cart-1
- COMP1
- HFH-1
- HNF-4alpha1
- HNF-4alpha2
- IRF-7A
- POU3F2
- POU3F2 (N-Oct-5a)
- POU3F2 (N-Oct-5b)
Genomic Locations for SERPINB10 Gene
Genomic Locations for SERPINB10 Gene
- chr18:63,897,174-63,936,111
- (GRCh38/hg38)
- Size:
- 38,938 bases
- Orientation:
- Plus strand
- chr18:61,564,408-61,603,345
- (GRCh37/hg19)
- Size:
- 38,938 bases
- Orientation:
- Plus strand
Genomic View for SERPINB10 Gene
Genes around SERPINB10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18q21.3 by HGNC
- 18q22.1 by Entrez Gene
- 18q21.33 by Ensembl
SERPINB10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SERPINB10 Gene
Proteins for SERPINB10 Gene
-
Protein details for SERPINB10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P48595-SPB10_HUMAN
- Recommended name:
- Serpin B10
- Protein Accession:
- P48595
- Q4VAX4
- Q4VAX7
Protein attributes for SERPINB10 Gene
- Size:
- 397 amino acids
- Molecular mass:
- 45403 Da
- Quaternary structure:
- No Data Available
Protein Expression for SERPINB10 Gene
Post-translational modifications for SERPINB10 Gene
Other Protein References for SERPINB10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ SERPINB10 Antibody
- Creative Diagnostics Anti-SERPINB10 monoclonal antibody
- Creative Biolabs Recombinant Anti-Human SERPINB10 Antibody
- Novus Biologicals Antibodies for SERPINB10
- Invitrogen Antibodies for SERPINB10 (AFLGC-SERPINB10)
-
Santa Cruz Biotechnology (SCBT) Antibodies for SERPINB10
- Sino Biological Antibodies for SERPINB10
Protein Products
-
OriGene Purified Proteins for SERPINB10
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-
Signalway Proteins for SERPINB10
-
Abcam proteins for SERPINB10
Assay Products
- antibodies-online: Show 7 available SERPINB10 Elisa Kits ranked by validation data
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-
Quality Products:
No data available for DME Specific Peptides for SERPINB10 Gene
Domains & Families for SERPINB10 Gene
Gene Families for SERPINB10 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for SERPINB10 Gene
- Blocks:
-
- Serpin
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SERPINB10 Gene
- GenScript: Design optimal peptide antigens:
-
- Serpin peptidase inhibitor, clade B (Ovalbumin), member 10 (Q4VAX6_HUMAN)
- Peptidase inhibitor 10 (SPB10_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P48595- Family:
-
- Belongs to the serpin family. Ov-serpin subfamily.
Function for SERPINB10 Gene
Molecular function for SERPINB10 Gene
- UniProtKB/Swiss-Prot Function:
- Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.
Phenotypes From GWAS Catalog for SERPINB10 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004867 | serine-type endopeptidase inhibitor activity | IBA | 21873635 |
| GO:0030414 | peptidase inhibitor activity | IEA | -- |
Phenotypes for SERPINB10 Gene
- MGI mutant phenotypes for SERPINB10:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SERPINB10:
-
- Decreased POU5F1-GFP protein expression
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased viability
- no effect
- Decreased viability after sindbis virus (SIN) dsTE12Q infection
- Decreased Sindbis virus (SIN) capsid and autophagosome LC3 protein colocalization
- Decreased mitophagy mCherry-Parkin protein expression after carbonyl cyanide m-chlorphenylhydrazone (CCCP) stimulation
- Decreased hepcidin::fluc mRNA expression
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SERPINB10 - Select products 50% OFF >
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-
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- Overview of 129 available SERPINB10 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SERPINB10
miRNA for SERPINB10 Gene
- miRTarBase miRNAs that target SERPINB10
miRNA Products
Inhibitory RNA Products
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- Overview of 129 available SERPINB10 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for SERPINB10 - Select products 50% OFF >
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Cell Line Products
-
Horizon Cell Lines for SERPINB10
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SERPINB10 Gene
Localization for SERPINB10 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SERPINB10 Gene
- Nucleus. Cytoplasm. Note=Mostly found in the nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| plasma membrane | 4 |
| extracellular | 4 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cytosol (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for SERPINB10 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Amoebiasis | ||
Pathways by source for SERPINB10 Gene
3 Reactome pathways for SERPINB10 Gene
1 KEGG pathway for SERPINB10 Gene
Interacting Proteins for SERPINB10 Gene
GPS-Prot Interaction Network for SERPINB10
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010466 | negative regulation of peptidase activity | IEA | -- |
| GO:0010951 | negative regulation of endopeptidase activity | IBA | 21873635 |
| GO:0043066 | negative regulation of apoptotic process | IEA | -- |
| GO:0043312 | neutrophil degranulation | TAS | -- |
No data available for SIGNOR curated interactions for SERPINB10 Gene
Transcripts for SERPINB10 Gene
mRNA/cDNA for SERPINB10 Gene
- 1 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000238508 2155 bps (ENST00000238508.8)
- ENST00000397996 840 bps (ENST00000397996.6)
- ENST00000418725 759 bps (ENST00000418725.1)
- ENST00000619595 1194 bps (ENST00000619595.1)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SERPINB10 - Select products 50% OFF >
- * SERPINB10 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SERPINB10
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- Overview of 129 available SERPINB10 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SERPINB10
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SERPINB10
- Browse OriGene Inhibitory RNA Products For SERPINB10
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SERPINB10
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- Overview of 129 available SERPINB10 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for SERPINB10 - Select products 50% OFF >
- * SERPINB10 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for SERPINB10
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SERPINB10
Relevant External Links for SERPINB10 Gene
- GeneLoc Exon Structure for
- SERPINB10
Expression for SERPINB10 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for SERPINB10 Gene
This gene is overexpressed in Whole Blood (x21.6).
This gene is overexpressed in Monocytes (27.3), Peripheral blood mononuclear cells (19.9), and Neutrophil (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SERPINB10 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SERPINB10
SOURCE GeneReport for Unigene cluster for SERPINB10 Gene:
Hs.158339mRNA Expression by UniProt/SwissProt for SERPINB10 Gene:
P48595-SPB10_HUMAN
Tissue specificity:
Expressed specifically in myeloid cells and the bone marrow.
Evidence on tissue expression from TISSUES for SERPINB10 Gene
- Bone marrow(4.4)
Primer Products
-
OriGene qPCR primer pairs for SERPINB10
-
OriGene qPCR primer pairs and template standards for SERPINB10
- genomics-online: primer clones - Search for available SERPINB10 Primer products
- Overview of 129 available SERPINB10 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for SERPINB10 Gene
Orthologs for SERPINB10 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SERPINB10 31 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SERPINB10 31 30 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SERPINB10 31 30 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Serpinb10 17 31 31 30 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Serpinb10 30 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | SERPINB10 31 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LOC101749622 30 |
|
||
| -- 31 |
|
OneToMany | |||
| SERPINB10 31 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | SERPINB10 31 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | serpinb1l1 31 |
|
ManyToMany | |
| serpinb1l4 31 |
|
ManyToMany | |||
| zgc:173729 31 |
|
ManyToMany | |||
| si:ch73-303g23.4 31 |
|
ManyToMany | |||
| serpinb1l3 31 |
|
ManyToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | Spn4 32 |
|
|
|
| CG9455 32 |
|
|
|||
| Spn2 32 |
|
|
|||
| Spn3 32 |
|
|
|||
| Spn43Aa 32 |
|
|
|||
| nec 32 |
|
|
- Species where no ortholog for SERPINB10 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for SERPINB10 Gene
- ENSEMBL:
- Gene Tree for SERPINB10 (if available)
- TreeFam:
- Gene Tree for SERPINB10 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SERPINB10: view image
Paralogs for SERPINB10 Gene
Paralogs for SERPINB10 Gene
- SERPINB2 5
- SERPINB1 5
- SERPINB3 5
- SERPINB6 5
- SERPINB4 5
- SERPINB13 5
- SERPINB8 5
- SERPINB9 5
- SERPINB12 5
- SERPINB5 5
- SERPINB7 5
- SERPINB11 5
- SERPINC1 5
- SERPINA3 5
- SERPINI2 5
- SERPINA7 5
- SERPINA5 5
- SERPINA11 5
- SERPINA1 5
- SERPINA9 5
- SERPINI1 5
- SERPINE2 5
- SERPINA6 5
- SERPINA4 5
- SERPIND1 5
- SERPINE1 5
- SERPINA12 5
- SERPINH1 5
- SERPINA10 5
- SERPING1 5
- SERPINF2 5
- SERPINE3 5
- SERPINF1 5
- AGT 5
- SERPINA2 5
- HMSD 5
(36) SIMAP similar genes for SERPINB10 Gene using alignment to 4 proteins:
- SPB10_HUMAN
- H7BYS2_HUMAN
- H7C004_HUMAN
- Q4VAX6_HUMAN
- SERPINB2
- PLANH2
- SERPINB13
- DKFZp686O07189
- DKFZp686D06190
- SERPINB1
- SERPINB11
- SERPINB8
- SERPINB9
- SERPINB12
- SERPINB4
- AT3
- SERPINB3
- SERPINB6
- SCCA2
- SERPINB7
- SERPINI2
- SERPINB5
- SERPINA1
- SERPINC1
- SERPINA5
- SERPINA12
- SERPINI1
- SERPINA3
- SERPINA9
- SERPINA11
- SERPINA7
- HMSD
- AAT
- SERPIND1
- SERPINA4
- SERPINE2
- SERPINE1
- SERPINA6
- SERPINH1
- ra-a47
Variants for SERPINB10 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SERPINB10 Gene
| SNP ID | Clinical significance and condition | Chr 18 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs17072097 | - | p.Ser3Ala | |||
| rs17072146 | - | p.Gly135Asp | |||
| rs35453062 | - | p.Asp360Asn | |||
| rs724558 | - | p.Ile99Thr | |||
| rs8097425 | - | p.Ile41Met |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv21739 | CNV | gain | 19812545 |
| esv2758730 | CNV | loss | 17122850 |
| esv3642785 | CNV | gain | 21293372 |
| esv3642788 | CNV | gain | 21293372 |
| nsv1066552 | CNV | gain | 25217958 |
| nsv1067311 | CNV | loss | 25217958 |
| nsv525889 | CNV | loss | 19592680 |
| nsv833673 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
92.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
22.91;
99.49% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SERPINB10 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SERPINB10
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SERPINB10 Gene
Disorders for SERPINB10 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chronic myelomonocytic leukemia |
|
|
| cardiomyopathy, familial hypertrophic, 1 |
|
|
Search SERPINB10 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SERPINB10
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for SERPINB10 Gene
Publications for SERPINB10 Gene
- Protease inhibitor 10 inhibits tumor necrosis factor alpha -induced cell death. Evidence for the formation of intracellular high M(r) protease inhibitor 10-containing complexes. (PMID: 10871600) Schleef RR … Chuang TL (The Journal of biological chemistry 2000) 2 3 4 23 54
- Bomapin is a redox-sensitive nuclear serpin that affects responsiveness of myeloid progenitor cells to growth environment. (PMID: 20433722) Przygodzka P … Wilczynska M (BMC cell biology 2010) 3 4 23 54
- Nucleotide variations in genes encoding plasminogen activator inhibitor-2 and serine proteinase inhibitor B10 associated with prostate cancer. (PMID: 16172807) Shioji G … Emi M (Journal of human genetics 2005) 3 23 41 54
- Identification of a nuclear targeting domain in the insertion between helices C and D in protease inhibitor-10. (PMID: 10196205) Chuang TL … Schleef RR (The Journal of biological chemistry 1999) 3 4 23 54
- Molecular cloning of bomapin (protease inhibitor 10), a novel human serpin that is expressed specifically in the bone marrow. (PMID: 7592909) Riewald M … Schleef RR (The Journal of biological chemistry 1995) 3 4 23 54
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- antibodies-online: Show 6 available SERPINB10 Antibodies ranked by validation data
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SERPINB10
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SERPINB10
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SERPINB10
- Search for SERPINB10 ELISA kits at Signalway
- Signalway Proteins for SERPINB10
Sources for SERPINB10 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
- (57) Tocris
- (58) Abcam
- (59) Novus Biologicals
- (60) ProSpec
- (61) Sino Biological
- (62) GenScript
- (63) Qiagen
- (64) OCA
- (65) Proteopedia
- (66) MOPED
- (67) neXtProt
- (68) Reactome
- (69) GeneGo (Thomson Reuters)
- (70) DISEASES
- (71) SIMAP
- (72) GenomeRNAi
- (73) LifeMap
- (74) miRTarBase
- (75) MalaCards
- (76) Invitrogen
- (77) BitterDB
- (78) ESI-BIO
- (79) RefSeq
- (80) BioSystems
- (81) MaxQB
- (82) IUPHAR
- (83) BioGPS
- (84) Illumina
- (85) COMPARTMENTS
- (86) HOMER
- (87) PaxDb
- (88) ApexBio
- (89) Addgene
- (90) antibodies-online
- (91) CYP
- (92) NONCODE
- (93) TreeFam
- (94) PathCards
- (95) GeneReviews
- (96) GeneTex
- (97) Taconic Biosciences
- (98) GTEx
- (99) ProteomicsDB
- (100) SCBT
- (101) DGIdb
- (102) ClinicalTrials
- (103) RVIS
- (104) SIGNOR
- (105) diseasecard
- (106) NIH Rare Diseases
- (107) Orphanet
- (108) UMLS
- (109) GTR
- (110) Disease Ontology
- (111) Genetics Home Reference
- (112) MeSH
- (113) MedlinePlus
- (114) CDC
- (115) NINDS
- (116) NCBI Bookshelf
- (117) ClinVar
- (118) Gene Damage Index
- (119) HPO
- (120) UDN
- (121) VISTA
- (122) FANTOM5
- (123) ENCODE
- (124) ProSci
- (125) Horizon
- (126) The Signaling Pathways Project (SPP)
- (127) IID
- (128) VectorBuilder
- (129) SNPedia
- (130) BRCA Exchange
- (131) CIViC
- (132) ProteoGenix
- (133) dbSUPER
- (134) TISSUES
- (135) Gene ORGANizer
- (136) abm
- (137) Human Protein Atlas
- (138) GWAS Catalog
- (139) Monarch Initiative
- (140) DataMed
- (141) HumanCyc
- (142) genomics-online
- (143) UCNEbase
- (144) EPDnew
- (145) Applied Biosystems
- (146) GlyConnect
- (147) Aminode
- (148) GeneCopoeia
- (149) GPS-Prot
- (150) RNACentral
- (151) LncRNADisease
- (152) LOVD
- (153) miR2Disease
- (154) DiseaseEnhancer
- (155) Boster Bio
- (156) Biorbyt
- (157) Biocompare
- (158) Mastermind
- (159) CTD^2 Dashboard
- (160) CraniofacialAtlas
- (161) GeneImprint
- (162) Synthego
- (163) Bio Basic
- (164) ENA
- (165) GtRNAdb
- (166) LncBase
- (167) LncBook
- (168) LNCipedia
- (169) LncRNAdb
- (170) Modomics
- (171) PDBe
- (172) Rfam
- (173) SILVA
- (174) snOPY
- (175) SRPDB
- (176) GENCODE
- (177) TarBase
- (178) MyBioSource
- (179) Signalway Antibody