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This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene... See more...
Aliases for SEPTIN5 Gene
Aliases for SEPTIN5 Gene
External Ids for SEPTIN5 Gene
- HGNC: 9164
- Entrez Gene: 5413
- Ensembl: ENSG00000184702
- OMIM: 602724
- UniProtKB: Q99719
Previous HGNC Symbols for SEPTIN5 Gene
- PNUTL1
- SEPT5
Summaries for SEPTIN5 Gene
-
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]
GeneCards Summary for SEPTIN5 Gene
SEPTIN5 (Septin 5) is a Protein Coding gene. Diseases associated with SEPTIN5 include Digeorge Syndrome and Early-Onset Parkinson's Disease. Among its related pathways are Actin Nucleation by ARP-WASP Complex and Parkinsons Disease Pathway. An important paralog of this gene is SEPT5-GP1BB.
UniProtKB/Swiss-Prot Summary for SEPTIN5 Gene
-
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity).
Additional gene information for SEPTIN5 Gene
- HGNC(9164)
- Entrez Gene(5413)
- Ensembl(ENSG00000184702)
- OMIM(602724)
- UniProtKB(Q99719)
- Open Targets Platform(ENSG00000184702)
- Monarch Initiative
- Search for SEPTIN5 at DataMed
- Search for SEPTIN5 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SEPTIN5 Gene
Genomics for SEPTIN5 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SEPTIN5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SEPTIN5 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SEPTIN5
Genomic Locations for SEPTIN5 Gene
Genomic Locations for SEPTIN5 Gene
- chr22:19,714,503-19,724,224
- (GRCh38/hg38)
- Size:
- 9,722 bases
- Orientation:
- Plus strand
- chr22:19,701,987-19,712,295
- (GRCh37/hg19)
- Size:
- 10,309 bases
- Orientation:
- Plus strand
Genomic View for SEPTIN5 Gene
Genes around SEPTIN5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q11.21 by HGNC
- 22q11.21 by Entrez Gene
- 22q11.21 by Ensembl
SEPTIN5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SEPTIN5 Gene
Proteins for SEPTIN5 Gene
-
Protein details for SEPTIN5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99719-SEPT5_HUMAN
- Recommended name:
- Septin-5
- Protein Accession:
- Q99719
- O15251
- Q96MY5
Protein attributes for SEPTIN5 Gene
- Size:
- 369 amino acids
- Molecular mass:
- 42777 Da
- Quaternary structure:
-
- Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity). Interacts with SEPTIN2 and SEPTIN5. In platelets, associated with a complex containing STX4. Interacts with PRKN. This interaction leads to SEPTIN5 ubiquitination and degradation (By similarity).
- Miscellaneous:
-
- In a heterologous system, SEPTIN5 overexpression has been shown to exert dopamine-dependent neurotoxicity. As wild-type PRKN, but not familial-linked PRKN mutants, ubiquitinates mouse SEPTIN5 and promotes its degradation, it has been suggested that a deficiency in SEPTIN5 degradation may contribute to the development of early onset Parkinson disease 2 (PARK2).
Post-translational modifications for SEPTIN5 Gene
- In platelets, phosphorylated in response to thrombin, phorbol-12-myristate-13-acetate and collagen.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for SEPTIN5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences SEPT5 / Septin 5 Monoclonal Antibody
- G Biosciences Immunotag™ SEPT5 Antibody
- Creative Diagnostics Anti-SEPT5 (aa 1-30) polyclonal antibody
- Creative Biolabs Recombinant Mouse anti-Human SEPT5 Monoclonal antibody (TD)
- GeneTex Anti-SEPT5 antibody [N3C3] and Anti-SEPT5 antibody
-
Custom Antibody ServicesOriGene Antibodies for SEPTIN5
- Novus Biologicals Antibodies for SEPTIN5
-
Abcam antibodies for SEPTIN5
- Invitrogen Antibodies for SEPTIN5 (AFLGC-SEPTIN5)
-
Biorbyt antibodies for SEPTIN5
Protein Products
-
OriGene Purified Proteins for SEPTIN5
- Search Origene for MassSpec and Protein Over-expression Lysates for SEPTIN5
- Origene Custom Protein Services for SEPTIN5
- ProSpec Recombinant Proteins for SEPTIN5
-
Signalway Proteins for SEPTIN5
-
Abcam proteins for SEPTIN5
Assay Products
- G Biosciences Immunotag™ Human SEPT5 (Septin-5) ELISA and Immunotag™ Septin-5 ELISA Kit
No data available for DME Specific Peptides for SEPTIN5 Gene
Domains & Families for SEPTIN5 Gene
Gene Families for SEPTIN5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SEPTIN5 Gene
- InterPro:
- Blocks:
-
- Cell division/GTP binding protein
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
Q99719UniProtKB/Swiss-Prot:
SEPT5_HUMAN :- Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
- Family:
-
- Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
No data available for Suggested Antigen Peptide Sequences for SEPTIN5 Gene
Function for SEPTIN5 Gene
Molecular function for SEPTIN5 Gene
- UniProtKB/Swiss-Prot Function:
- Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity).
Phenotypes From GWAS Catalog for SEPTIN5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003924 | GTPase activity | TAS | 21563316 |
| GO:0005198 | structural molecule activity | TAS | 9611266 |
| GO:0005515 | protein binding | IPI | 10321247 |
| GO:0005525 | GTP binding | IEA | -- |
Phenotypes for SEPTIN5 Gene
- MGI mutant phenotypes for SEPTIN5:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for SEPTIN5:
Animal Models for SEPTIN5 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SEPTIN5 - Select products 50% OFF >
- * SEPTIN5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SEPTIN5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEPTIN5
miRNA for SEPTIN5 Gene
- miRTarBase miRNAs that target SEPTIN5
miRNA Products
Inhibitory RNA Products
- Origene shrna and sirna products in human, mouse, rat for SEPTIN5
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Clone Products
- Applied Biological Materials (abm): Clones for SEPTIN5 - Select products 50% OFF >
- * SEPTIN5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SEPTIN5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEPTIN5
Cell Line Products
-
Horizon Cell Lines for SEPTIN5
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SEPTIN5 Gene
Localization for SEPTIN5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SEPTIN5 Gene
- Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytoskeleton | 5 |
| nucleus | 3 |
| cytosol | 3 |
| extracellular | 2 |
| mitochondrion | 2 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| peroxisome | 0 |
- Actin filaments (2)
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0005886 | plasma membrane | IDA | 10321247 |
| GO:0005940 | septin ring | IBA | 21873635 |
| GO:0008021 | synaptic vesicle | IDA | 10321247 |
Pathways & Interactions for SEPTIN5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway |
Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
.97
|
|
| 2 | Parkinson disease | ||
| 3 | Chks in Checkpoint Regulation |
Parkinson's Disease Pathway
.30
|
|
| 4 | ERK Signaling |
Rho Family GTPases
.61
|
|
| 5 | Actin Nucleation by ARP-WASP Complex |
RhoA Pathway
.35
|
|
Pathways by source for SEPTIN5 Gene
2 BioSystems pathways for SEPTIN5 Gene
1 KEGG pathway for SEPTIN5 Gene
2 GeneGo (Thomson Reuters) pathways for SEPTIN5 Gene
- Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway
- Proteolysis_Putative ubiquitin pathway
3 Qiagen pathways for SEPTIN5 Gene
- Parkinson's Disease Pathway
- Rho Family GTPases
- RhoA Pathway
Interacting Proteins for SEPTIN5 Gene
Selected Interacting proteins:
Q99719-SEPT5_HUMAN
ENSP00000391311
for SEPTIN5 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for SEPTIN5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007049 | cell cycle | IEA | -- |
| GO:0016080 | synaptic vesicle targeting | TAS | 10321247 |
| GO:0017157 | regulation of exocytosis | IMP | 10321247 |
| GO:0030534 | adult behavior | ISS | -- |
| GO:0034613 | cellular protein localization | IBA | 21873635 |
No data available for SIGNOR curated interactions for SEPTIN5 Gene
Transcripts for SEPTIN5 Gene
mRNA/cDNA for SEPTIN5 Gene
- 2 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 13 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000383045 1588 nts (view in UCSC)
- ENST00000395109 794 nts (view in UCSC)
- ENST00000406172 1996 nts (view in UCSC)
- ENST00000406395 1974 nts (view in UCSC)
- ENST00000412544 1108 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SEPTIN5 - Select products 50% OFF >
- * SEPTIN5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SEPTIN5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEPTIN5
miRNA Products
Inhibitory RNA Products
- Origene shrna and sirna products in human, mouse, rat for SEPTIN5
- Browse OriGene Inhibitory RNA Products For SEPTIN5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEPTIN5
Clone Products
- Applied Biological Materials (abm): Clones for SEPTIN5 - Select products 50% OFF >
- * SEPTIN5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SEPTIN5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEPTIN5
Relevant External Links for SEPTIN5 Gene
- GeneLoc Exon Structure for
- SEPTIN5
Expression for SEPTIN5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Gut Tube (Gastrointestinal Tract)
- Lung (Respiratory System)
- Bone (Muscoskeletal System)
- Eye (Sensory Organs)
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SEPTIN5
SOURCE GeneReport for Unigene cluster for SEPTIN5 Gene:
Hs.728762mRNA Expression by UniProt/SwissProt for SEPTIN5 Gene:
Q99719-SEPT5_HUMAN
Tissue specificity:
Expressed at high levels in the CNS, as well as in heart and platelets (at protein level).
Evidence on tissue expression from TISSUES for SEPTIN5 Gene
- Nervous system(5)
- Heart(4.5)
- Blood(4.4)
- Lung(4.3)
- Skin(2.7)
- Muscle(2.6)
- Adrenal gland(2)
Primer Products
-
OriGene qPCR primer pairs for SEPTIN5
-
OriGene qPCR primer pairs and template standards for SEPTIN5
No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for SEPTIN5 Gene
Orthologs for SEPTIN5 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SEPT5 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SEPT5 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SEPT5 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Sept5 30 31 |
|
OneToOne | |
| Septin5 17 |
|
||||
| Rat (Rattus norvegicus) |
Mammalia | Sept5 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
| Chicken (Gallus gallus) |
Aves | SEP-05 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SEPT5 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | sept5 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | sept5b 31 |
|
OneToMany | |
| sept5a 31 |
|
OneToMany | |||
| -- 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Sep4 31 |
|
OneToMany |
- Species where no ortholog for SEPTIN5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SEPTIN5 Gene
- ENSEMBL:
- Gene Tree for SEPTIN5 (if available)
- TreeFam:
- Gene Tree for SEPTIN5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SEPTIN5: view image
Paralogs for SEPTIN5 Gene
Variants for SEPTIN5 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SEPTIN5 Gene
| SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 627512 | Conflicting Interpretations: Abnormal bleeding; Macrothrombocytopenia | 19,721,911(+) | GTGCACTACGAGAACT | ||
| 738672 | Likely Benign: not provided | 19,720,675(+) | G/A | INTRON_VARIANT | |
| 739548 | Likely Benign: not provided | 19,722,285(+) | G/A | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 744189 | Likely Benign: not provided | 19,721,697(+) | C/A | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 746563 | Likely Benign: not provided | 19,722,273(+) | C/A | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv725n67 | CNV | gain | 20364138 |
| esv2751940 | CNV | gain | 17911159 |
| esv3575418 | CNV | gain | 25503493 |
| esv3647279 | CNV | gain | 21293372 |
| esv3893434 | CNV | gain | 25118596 |
| nsv517478 | CNV | loss | 19592680 |
| nsv588216 | CNV | gain | 21841781 |
| nsv828938 | CNV | gain | 20364138 |
| nsv828939 | CNV | loss | 20364138 |
| nsv828943 | CNV | loss | 20364138 |
| nsv834128 | CNV | loss | 17160897 |
| nsv834129 | CNV | loss | 17160897 |
| nsv953023 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
11.4% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SEPTIN5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SEPTIN5
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SEPTIN5 Gene
Disorders for SEPTIN5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| digeorge syndrome |
|
|
| early-onset parkinson's disease |
|
|
| amyotrophic neuralgia |
|
|
| brachial plexus neuropathy |
|
|
| juvenile-onset parkinson's disease |
|
|
Search SEPTIN5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SEPTIN5
No data available for UniProtKB/Swiss-Prot and Genatlas for SEPTIN5 Gene
Publications for SEPTIN5 Gene
- Structure and expression of the human septin gene HCDCREL-1. (PMID: 9611266) Yagi M … Ware J (Gene 1998) 2 3 4
- A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11. (PMID: 9385360) McKie JM … Scambler PJ (Human genetics 1997) 2 3 4
- Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis. (PMID: 18385322) Amin ND … Pant HC (The Journal of neuroscience : the official journal of the Society for Neuroscience 2008) 3 23
- Septin expression in proliferative retinal membranes. (PMID: 17625225) Xin X … Meyer P (The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007) 3 23
- Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5. (PMID: 16767699) Bläser S … Zieger B (The Journal of pathology 2006) 3 23
ExternalLinks
Products for SEPTIN5 Gene
- Custom Antibody ServicesOriGene Antibodies for SEPTIN5
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- Custom Assay Services
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- OriGene qPCR primer pairs for SEPTIN5
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- OriGene CRISPR knockouts for SEPTIN5
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SEPTIN5
- Sino Biological Human cDNA Clone for SEPTIN5
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SEPTIN5
- Novus Biologicals proteins and lysates for SEPTIN5
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SEPTIN5
- Abcam proteins for SEPTIN5
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for SEPTIN5 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SEPTIN5 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SEPTIN5 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SEPTIN5 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SEPTIN5
- antibodies-online: Show 20 available SEPT5 Antibodies ranked by validation data
- Compare Top SEPT5 Antibodies
- antibodies-online: Show 15 available SEPT5 Elisa Kits ranked by validation data
- Compare Top SEPT5 Elisa Kits
- antibodies-online: Show 11 available SEPT5 Proteins ranked by validation data
- Compare Top SEPT5 Proteins
- Horizon Cell Lines for SEPTIN5
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEPTIN5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEPTIN5
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SEPTIN5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEPTIN5
- Biorbyt antibodies for SEPTIN5
Sources for SEPTIN5 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
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