Aliases for SEPTIN11 Gene
External Ids for SEPTIN11 Gene
Previous HGNC Symbols for SEPTIN11 Gene
SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM, Jul 2009]
GeneCards Summary for SEPTIN11 Gene
SEPTIN11 (Septin 11) is a Protein Coding gene. Diseases associated with SEPTIN11 include Chronic Neutrophilic Leukemia and Amyotrophic Neuralgia. Among its related pathways are Actin Nucleation by ARP-WASP Complex and Shigellosis. An important paralog of this gene is SEPTIN6.
UniProtKB/Swiss-Prot Summary for SEPTIN11 Gene
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.