Free for academic non-profit institutions. Other users need a Commercial license
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but ... See more...
Aliases for SEPTIN1 Gene
Aliases for SEPTIN1 Gene
External Ids for SEPTIN1 Gene
- HGNC: 2879
- Entrez Gene: 1731
- Ensembl: ENSG00000180096
- OMIM: 612897
- UniProtKB: Q8WYJ6
Previous HGNC Symbols for SEPTIN1 Gene
- DIFF6
- SEPT1
Summaries for SEPTIN1 Gene
-
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]
GeneCards Summary for SEPTIN1 Gene
SEPTIN1 (Septin 1) is a Protein Coding gene. Diseases associated with SEPTIN1 include Febrile Seizures, Familial, 4 and Febrile Seizures, Familial, 1. Among its related pathways are Bacterial invasion of epithelial cells and Aurora B signaling. An important paralog of this gene is SEPTIN5.
UniProtKB/Swiss-Prot Summary for SEPTIN1 Gene
-
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Additional gene information for SEPTIN1 Gene
- HGNC(2879)
- Entrez Gene(1731)
- Ensembl(ENSG00000180096)
- OMIM(612897)
- UniProtKB(Q8WYJ6)
- Open Targets Platform(ENSG00000180096)
- Search for SEPTIN1 at DataMed
- Search for SEPTIN1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SEPTIN1 Gene
Genomics for SEPTIN1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SEPTIN1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SEPTIN1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SEPTIN1
Genomic Locations for SEPTIN1 Gene
Genomic Locations for SEPTIN1 Gene
- chr16:30,378,133-30,395,991
- (GRCh38/hg38)
- Size:
- 17,859 bases
- Orientation:
- Minus strand
- chr16:30,389,454-30,407,312
- (GRCh37/hg19)
- Size:
- 17,859 bases
- Orientation:
- Minus strand
Genomic View for SEPTIN1 Gene
Genes around SEPTIN1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
SEPTIN1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SEPTIN1 Gene
Proteins for SEPTIN1 Gene
-
Protein details for SEPTIN1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WYJ6-SEPT1_HUMAN
- Recommended name:
- Septin-1
- Protein Accession:
- Q8WYJ6
- B4DVE6
- Q658T1
- Q8NEZ1
- Q96EL4
- Q9H285
Protein attributes for SEPTIN1 Gene
- Size:
- 367 amino acids
- Molecular mass:
- 41971 Da
- Quaternary structure:
-
- Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity). Interacts with AURKB.
- SequenceCaution:
-
- Sequence=AAK61491.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Post-translational modifications for SEPTIN1 Gene
Other Protein References for SEPTIN1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences SEPT1 / Septin 1 Antibody
- G Biosciences Immunotag™ Septin 1 Antibody
- Creative Diagnostics Anti-SEPT1 monoclonal antibody
- Creative Biolabs Mouse Anti-SEPT1 Recombinant Antibody (CBXS-3589)
-
Custom Antibody ServicesOriGene Antibodies for SEPTIN1
- Novus Biologicals Antibodies for SEPTIN1
- Invitrogen Antibodies for SEPTIN1 (AFLGC-SEPTIN1)
-
Boster Bio Antibodies for SEPTIN1
-
Custom Antibody ServicesProSci Antibodies for SEPTIN1
Protein Products
- Creative Biomart Recombinant Human SEPT1, HIS-tagged
- Search Origene for MassSpec and Protein Over-expression Lysates for SEPTIN1
- Origene Custom Protein Services for SEPTIN1
- antibodies-online: Show 6 available SEPT1 Proteins ranked by validation data
- Compare Top SEPT1 Proteins
-
Quality Products:
-
Signalway Proteins for SEPTIN1
-
Abcam proteins for SEPTIN1
Assay Products
- Creative Diagnostics Human SEPT1 ELISA Matched Antibody Pair
- antibodies-online: Show 1 available SEPT1 Elisa Kits ranked by validation data
- Compare Top SEPT1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SEPTIN1 Gene
Domains & Families for SEPTIN1 Gene
Gene Families for SEPTIN1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SEPTIN1 Gene
- InterPro:
- Blocks:
-
- Cell division/GTP binding protein
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
Q8WYJ6UniProtKB/Swiss-Prot:
SEPT1_HUMAN :- Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
- Family:
-
- Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
No data available for Suggested Antigen Peptide Sequences for SEPTIN1 Gene
Function for SEPTIN1 Gene
Molecular function for SEPTIN1 Gene
- UniProtKB/Swiss-Prot Function:
- Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Phenotypes From GWAS Catalog for SEPTIN1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003924 | GTPase activity | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 16179162 |
| GO:0005525 | GTP binding | IEA | -- |
| GO:0042802 | identical protein binding | IPI | 16189514 |
Phenotypes for SEPTIN1 Gene
- GenomeRNAi human phenotypes for SEPTIN1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SEPTIN1 - Select products 50% OFF >
- * SEPTIN1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SEPTIN1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEPTIN1
miRNA for SEPTIN1 Gene
- miRTarBase miRNAs that target SEPTIN1
miRNA Products
Inhibitory RNA Products
- Origene shrna and sirna products in human, mouse, rat for SEPTIN1
- Browse OriGene Inhibitory RNA Products For SEPTIN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEPTIN1
Clone Products
- Applied Biological Materials (abm): Clones for SEPTIN1 - Select products 50% OFF >
- * SEPTIN1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SEPTIN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEPTIN1
Cell Line Products
-
Horizon Cell Lines for SEPTIN1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SEPTIN1 Gene
Localization for SEPTIN1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SEPTIN1 Gene
- Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 3 |
| nucleus | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Actin filaments (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005623 | cell | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005815 | microtubule organizing center | IEA | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0005940 | septin ring | IBA | 21873635 |
Pathways & Interactions for SEPTIN1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Bacterial invasion of epithelial cells | ||
| 2 | Aurora B signaling | ||
Pathways by source for SEPTIN1 Gene
1 BioSystems pathway for SEPTIN1 Gene
1 KEGG pathway for SEPTIN1 Gene
Interacting Proteins for SEPTIN1 Gene
Selected Interacting proteins:
Q8WYJ6-SEPT1_HUMAN
ENSP00000324511
for SEPTIN1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SEPTIN1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007056 | spindle assembly involved in female meiosis | IEA | -- |
| GO:0017157 | regulation of exocytosis | IBA | 21873635 |
| GO:0034613 | cellular protein localization | IBA | 21873635 |
| GO:0051301 | cell division | IEA | -- |
No data available for SIGNOR curated interactions for SEPTIN1 Gene
Drugs & Compounds for SEPTIN1 Gene
No Compound Related Data Available
Drug Products
- Creative Biomart Recombinant Human SEPT1, HIS-tagged
Transcripts for SEPTIN1 Gene
mRNA/cDNA for SEPTIN1 Gene
- 2 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 11 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000321367 1592 nts (view in UCSC)
- ENST00000562152 467 nts (view in UCSC)
- ENST00000563743 620 nts (view in UCSC)
- ENST00000563957 2738 nts (view in UCSC)
- ENST00000566517 1080 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SEPTIN1 - Select products 50% OFF >
- * SEPTIN1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SEPTIN1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEPTIN1
miRNA Products
Inhibitory RNA Products
- Origene shrna and sirna products in human, mouse, rat for SEPTIN1
- Browse OriGene Inhibitory RNA Products For SEPTIN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEPTIN1
Clone Products
- Applied Biological Materials (abm): Clones for SEPTIN1 - Select products 50% OFF >
- * SEPTIN1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SEPTIN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEPTIN1
Relevant External Links for SEPTIN1 Gene
- GeneLoc Exon Structure for
- SEPTIN1
Expression for SEPTIN1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SEPTIN1
SOURCE GeneReport for Unigene cluster for SEPTIN1 Gene:
Hs.632176mRNA Expression by UniProt/SwissProt for SEPTIN1 Gene:
Q8WYJ6-SEPT1_HUMAN
Tissue specificity:
Expressed at high levels in lymphoid and hematopoietic tissues.
Evidence on tissue expression from TISSUES for SEPTIN1 Gene
- Liver(4.3)
- Spleen(4.3)
- Stomach(4.2)
- Muscle(3.1)
- Intestine(3)
- Blood(2.6)
- Nervous system(2.1)
Primer Products
-
OriGene qPCR primer pairs for SEPTIN1
-
OriGene qPCR primer pairs and template standards for SEPTIN1
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for SEPTIN1 Gene
Orthologs for SEPTIN1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SEPT1 30 |
|
||
| -- 31 |
|
OneToMany | |||
| Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
| SEPT1 30 |
|
||||
| Cow (Bos Taurus) |
Mammalia | SEPT1 30 31 |
|
OneToMany | |
| Rat (Rattus norvegicus) |
Mammalia | Sept1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Sept1 30 31 |
|
OneToMany | |
| Septin1 17 |
|
||||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| Zebrafish (Danio rerio) |
Actinopterygii | sept7b 31 |
|
ManyToMany | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | Sep4 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SPR28 33 |
|
|
- Species where no ortholog for SEPTIN1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SEPTIN1 Gene
- ENSEMBL:
- Gene Tree for SEPTIN1 (if available)
- TreeFam:
- Gene Tree for SEPTIN1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SEPTIN1: view image
Paralogs for SEPTIN1 Gene
Variants for SEPTIN1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SEPTIN1 Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs34518080 | - | p.Gly80Val |
Residual Variation Intolerance Score:
58.2% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SEPTIN1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SEPTIN1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SEPTIN1 Gene
Disorders for SEPTIN1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| febrile seizures, familial, 4 |
|
|
| febrile seizures, familial, 1 |
|
|
| amyotrophic neuralgia |
|
|
| brachial plexus neuropathy |
|
|
| yaws |
|
|
Search SEPTIN1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SEPTIN1
No data available for UniProtKB/Swiss-Prot and Genatlas for SEPTIN1 Gene
Publications for SEPTIN1 Gene
- From midbody protein-protein interaction network construction to novel regulators in cytokinesis. (PMID: 19799413) Chen TC … Huang CY (Journal of proteome research 2009) 3 4
- Septin1, a new interaction partner for human serine/threonine kinase aurora-B. (PMID: 16179162) Qi M … Yu L (Biochemical and biophysical research communications 2005) 3 4
- Expression profiling the human septin gene family. (PMID: 15915442) Hall PA … Russell SE (The Journal of pathology 2005) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression. (PMID: 12747765) Scanlan MJ … Old LJ (Cancer immunity 2001) 3 4
ExternalLinks
Products for SEPTIN1 Gene
- Custom Antibody ServicesOriGene Antibodies for SEPTIN1
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for SEPTIN1
- Origene Custom Protein Services for SEPTIN1
- Origene shrna and sirna products in human, mouse, rat for SEPTIN1
- Browse OriGene Inhibitory RNA Products For SEPTIN1
- OriGene qPCR primer pairs for SEPTIN1
- OriGene qPCR primer pairs and template standards for SEPTIN1
- OriGene CRISPR knockouts for SEPTIN1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SEPTIN1
- Sino Biological Human cDNA Clone for SEPTIN1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SEPTIN1
- Novus Biologicals proteins and lysates for SEPTIN1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for SEPTIN1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for SEPTIN1 (AFLGC-SEPTIN1)
- VectorBuilder Custom and pre-made DNA vectors for SEPTIN1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SEPTIN1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SEPTIN1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SEPTIN1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SEPTIN1
- antibodies-online: Show 22 available SEPT1 Antibodies ranked by validation data
- Compare Top SEPT1 Antibodies
- antibodies-online: Show 1 available SEPT1 Elisa Kits ranked by validation data
- Compare Top SEPT1 Elisa Kits
- Quality Products:
- antibodies-online: Show 6 available SEPT1 Proteins ranked by validation data
- Compare Top SEPT1 Proteins
- Quality Products:
- Custom Antibody ServicesProSci Antibodies for SEPTIN1
- Search for SEPTIN1 Proteins at ProSci
- Horizon Cell Lines for SEPTIN1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEPTIN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEPTIN1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SEPTIN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEPTIN1
Sources for SEPTIN1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB