Subcategory (RNA class) for SEPT5-GP1BB Gene
Aliases for SEPT5-GP1BB Gene
External Ids for SEPT5-GP1BB Gene
Previous GeneCards Identifiers for SEPT5-GP1BB Gene
This locus represents naturally occurring read-through transcription between the neighboring SEPT5 (septin 5) and GP1BB (glycoprotein Ib (platelet), beta polypeptide) genes on chromosome 22. This read-through transcription arises from inefficient use of an imperfect polyA signal in the upstream SEPT5 gene, whereby transcription continues into the GP1BB gene. Alternative splicing results in multiple read-through variants. The read-through transcripts are candidates for nonsense-mediated mRNA decay (NMD), and are therefore unlikely to produce protein products. [provided by RefSeq, Dec 2010]
GeneCards Summary for SEPT5-GP1BB Gene
SEPT5-GP1BB (SEPT5-GP1BB Readthrough) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with SEPT5-GP1BB include Bernard-Soulier Syndrome. An important paralog of this gene is SEPTIN5.