External Ids for SEPT11 Gene
Previous GeneCards Identifiers for SEPT11 Gene
SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM, Jul 2009]
GeneCards Summary for SEPT11 Gene
SEPT11 (Septin 11) is a Protein Coding gene. Diseases associated with SEPT11 include Chronic Neutrophilic Leukemia. Among its related pathways are Bacterial invasion of epithelial cells. Gene Ontology (GO) annotations related to this gene include GTP binding. An important paralog of this gene is SEPT6.
UniProtKB/Swiss-Prot for SEPT11 Gene
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.