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Aliases for SENCR Gene
Data sources for SENCR Gene:
Subcategory (RNA class) for SENCR Gene
lncRNA
Aliases for SENCR Gene
- Smooth Muscle And Endothelial Cell Enriched Migration/Differentiation-Associated LncRNA (HGNC, NCBI Entrez Gene, Ensembl)
- Smooth Muscle And Endothelial Cell Enriched Migration/Differentiation-Associated Long Non-Coding RNA (HGNC, NCBI Entrez Gene)
- FLI1 Antisense RNA 1 (Non-Protein Coding) (HGNC, NCBI Entrez Gene)
- SENCR (Ensembl, LNCipedia)
- FLI1 Antisense RNA 1 (HGNC)
- NONHSAG010021.2 (NONCODE)
- HSALNG0088110 (LncBook)
- FLI1-AS1 (NCBI Entrez Gene)
- LncRNA9 (NCBI Entrez Gene)
External Ids for SENCR Gene
- HGNC: 44177
- NCBI Entrez Gene: 100507392
- Ensembl: ENSG00000254703
- OMIM®: 615815
Previous HGNC Symbols for SENCR Gene
- FLI1-AS1
Previous GeneCards Identifiers for SENCR Gene
- GC11M128564
Summaries for SENCR Gene
GeneCards Summary for SENCR Gene
SENCR (Smooth Muscle And Endothelial Cell Enriched Migration/Differentiation-Associated LncRNA) is an RNA Gene, and is affiliated with the lncRNA class.
Additional gene information for SENCR Gene
- HGNC (44177)
- NCBI Entrez Gene (100507392)
- Ensembl (ENSG00000254703)
- OMIM® (615815)
- Open Targets Platform(ENSG00000254703)
- Search for SENCR at DataMed
- Search for SENCR at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SENCR Gene
Genomics for SENCR Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SENCR Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SENCR on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for SENCR Gene
Latest Assembly
- chr11:128,691,671-128,696,030
- (GRCh38/hg38)
- Size:
- 4,360 bases
- Orientation:
- Minus strand
Previous Assembly
- chr11:128,561,567-128,565,918
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 4,352 bases
- Orientation:
- Minus strand
- chr11:128,561,567-128,565,918
- (GRCh37/hg19 by Ensembl)
- Size:
- 4,352 bases
- Orientation:
- Minus strand
Genomic View for SENCR Gene
Genes around SENCR on UCSC Golden Path with GeneCards custom track
SENCR in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
- Cytogenetic band:
-
- 11q24.3 by HGNC
- 11q24.3 by Entrez Gene
- 11q24.3 by Ensembl
SENCR Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SENCR Gene
Proteins for SENCR Gene
Post-translational modifications for SENCR Gene
No Post-translational modifications
No data available for DME Specific Peptides for SENCR Gene
Domains & Families for SENCR Gene
Gene Families for SENCR Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SENCR Gene
Function for SENCR Gene
Phenotypes From GWAS Catalog for SENCR Gene
CRISPR products for research
Inhibitory RNAs for research
Clone products for research
Cell Lines for research
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SENCR Gene
Localization for SENCR Gene
| Compartment | Confidence |
|---|---|
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SENCR Gene
Transcripts for SENCR Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for SENCR Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS0000602E27_9606 | lncRNA | 1298 | 3 |
Ensembl: ENST00000526269 (view in UCSC) , LNCipedia: SENCR:2, NONCODE: NONHSAT025072.2, |
| URS000075E93E_9606 | lncRNA | 1298 | 1 |
RefSeq: NR_038908, |
| URS00008BA62F_9606 | lncRNA | 1290 | 2 |
LncBook: HSALNT0183247, LNCipedia: SENCR:1, |
| URS00009BAA49_9606 | lncRNA | 1290 | 2 |
LncBook: HSALNT0183246, NONCODE: NONHSAT160892.1, |
| URS00007F6900_9606 | lncRNA | 1305 | 1 |
ENA: KF806591.1:1..1324:ncRNA, |
SENCR in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for SENCR Gene
- 2 NCBI additional mRNA sequence :
CRISPR products for research
Inhibitory RNAs for research
Clone products for research
Relevant External Links for SENCR Gene
- GeneLoc Exon Structure for
- SENCR
Expression for SENCR Gene
mRNA differential expression in normal tissues according to GTEx for SENCR Gene
This gene is overexpressed in Whole Blood (x7.9) and Spleen (x6.8).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SENCR
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SENCR Gene
Orthologs for SENCR Gene
No data available for Orthologs for SENCR Gene
Paralogs for SENCR Gene
No data available for Paralogs for SENCR Gene
Variants for SENCR Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SENCR Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1425813965 | Likely Benign: not provided | 128,694,270(-) |
T/C NM_002017.5(FLI1):c.12T>C (p.Thr4=) |
SYNONYMOUS_VARIANT,FIVE_PRIME_UTR_VARIANT,INTRON |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Additional Variant Information for SENCR Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SENCR
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SENCR Gene
Disorders for SENCR Gene
Additional Disease Information for SENCR
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for SENCR Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SENCR Gene
Publications for SENCR Gene
- Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA. (PMID: 24578380) Bell RD … Miano JM (Arteriosclerosis, thrombosis, and vascular biology 2014) 2 3
- SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4. (PMID: 30584103) Lyu Q … Miano JM (Proceedings of the National Academy of Sciences of the United States of America 2019) 3
- Long non‑coding RNA SENCR alleviates the inhibitory effects of rapamycin on human umbilical vein endothelial cells. (PMID: 29845247) Sun H … Song M (Molecular medicine reports 2018) 3
- Association of the rs555172 polymorphism in SENCR long non-coding RNA and atherosclerotic coronary artery disease. (PMID: 29118951) Shahmoradi N … Kheiry MA (Journal of cardiovascular and thoracic research 2017) 3
- A Role for the Long Noncoding RNA SENCR in Commitment and Function of Endothelial Cells. (PMID: 26898221) Boulberdaa M … Baker AH (Molecular therapy : the journal of the American Society of Gene Therapy 2016) 3
ExternalLinks
Products for SENCR Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SENCR
- Origene Custom Protein Services for SENCR
- Browse OriGene Inhibitory RNA Products For SENCR
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for SENCR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SENCR
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for SENCR
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for SENCR
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SENCR
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for SENCR
Sources for SENCR Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB