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Aliases for SEMA4C Gene
Aliases for SEMA4C Gene
External Ids for SEMA4C Gene
- HGNC: 10731
- Entrez Gene: 54910
- Ensembl: ENSG00000168758
- OMIM: 604462
- UniProtKB: Q9C0C4
Previous HGNC Symbols for SEMA4C Gene
- SEMAI
Previous GeneCards Identifiers for SEMA4C Gene
- GC02M095302
- GC02M095979
- GC02M096993
- GC02M097010
- GC02M096947
- GC02M096889
- GC02M097525
- GC02M091485
Summaries for SEMA4C Gene
GeneCards Summary for SEMA4C Gene
SEMA4C (Semaphorin 4C) is a Protein Coding gene. Diseases associated with SEMA4C include Cri-Du-Chat Syndrome and Kallmann Syndrome. Among its related pathways are Axon guidance. An important paralog of this gene is SEMA4G.
UniProtKB/Swiss-Prot Summary for SEMA4C Gene
-
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Additional gene information for SEMA4C Gene
- HGNC(10731)
- Entrez Gene(54910)
- Ensembl(ENSG00000168758)
- OMIM(604462)
- UniProtKB(Q9C0C4)
- Open Targets Platform(ENSG00000168758)
- Search for SEMA4C at DataMed
- Search for SEMA4C at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SEMA4C Gene
Genomics for SEMA4C Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SEMA4C Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SEMA4C on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SEMA4C
- Top Transcription factor binding sites by QIAGEN in the SEMA4C gene promoter:
-
- AhR
- Oct-B1
- oct-B2
- oct-B3
- POU2F1
- POU2F1a
- POU2F2
- POU2F2 (Oct-2.1)
- POU2F2B
- STAT5B
Genomic Locations for SEMA4C Gene
Genomic Locations for SEMA4C Gene
- chr2:96,859,718-96,870,943
- (GRCh38/hg38)
- Size:
- 11,226 bases
- Orientation:
- Minus strand
- chr2:97,525,453-97,536,494
- (GRCh37/hg19)
- Size:
- 11,042 bases
- Orientation:
- Minus strand
Genomic View for SEMA4C Gene
Genes around SEMA4C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q11.2 by HGNC
- 2q11.2 by Entrez Gene
- 2q11.2 by Ensembl
SEMA4C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SEMA4C Gene
Proteins for SEMA4C Gene
-
Protein details for SEMA4C Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9C0C4-SEM4C_HUMAN
- Recommended name:
- Semaphorin-4C
- Protein Accession:
- Q9C0C4
- Q32MJ3
- Q7Z5X0
Protein attributes for SEMA4C Gene
- Size:
- 833 amino acids
- Molecular mass:
- 92623 Da
- Quaternary structure:
-
- Interacts (via the PDZ-binding motif) with GIPC (via the PDZ domain) (By similarity). Interacts with NCDN (By similarity). Interacts (via the PDZ-binding motif) with DLG4. Interacts with PLXNB2 (By similarity).
Protein Expression for SEMA4C Gene
Post-translational modifications for SEMA4C Gene
Other Protein References for SEMA4C Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences SEMA4C / Semaphorin 4C Antibody
- G Biosciences Immunotag™ SEMA4C Antibody
-
Custom Antibody ServicesOriGene Antibodies for SEMA4C
- Novus Biologicals Antibodies for SEMA4C
- Invitrogen Antibodies for SEMA4C (AFLGC-SEMA4C)
- antibodies-online: Show 10 available SEMA4C Antibodies ranked by validation data
- Compare Top SEMA4C Antibodies
-
Recommended
- 34 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 5 IHC Antibodies (anti-human)
- 2 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-mouse)
- 9 WB Antibodies (anti-mouse)
- 8 FACS Antibodies (anti-mouse)
- 4 IHC Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 3 WB Antibodies (anti-rat)
-
Santa Cruz Biotechnology (SCBT) Antibodies for SEMA4C
Protein Products
-
OriGene Purified Proteins for SEMA4C
- Search Origene for MassSpec and Protein Over-expression Lysates for SEMA4C
- Origene Custom Protein Services for SEMA4C
-
Signalway Proteins for SEMA4C
Assay Products
- RayBiotech Human Semaphorin 4C ELISA
- antibodies-online: Show 11 available SEMA4C Elisa Kits ranked by validation data
- Compare Top SEMA4C Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SEMA4C Gene
Domains & Families for SEMA4C Gene
Gene Families for SEMA4C Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for SEMA4C Gene
- InterPro:
- Blocks:
-
- Immunoglobulin subtype
- Semaphorin/CD100 antigen
- ProtoNet:
Suggested Antigen Peptide Sequences for SEMA4C Gene
- GenScript: Design optimal peptide antigens:
-
- SEMA4C protein (Q6P5A5_HUMAN)
- Semaphorin-4C (SEM4C_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9C0C4- Family:
-
- Belongs to the semaphorin family.
Function for SEMA4C Gene
Molecular function for SEMA4C Gene
- UniProtKB/Swiss-Prot Function:
- Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Phenotypes From GWAS Catalog for SEMA4C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IEA,IPI | 25416956 |
| GO:0030215 | semaphorin receptor binding | IEA,IBA | 21873635 |
| GO:0045499 | chemorepellent activity | IBA | 21873635 |
Phenotypes for SEMA4C Gene
- MGI mutant phenotypes for SEMA4C:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for SEMA4C:
Animal Models for SEMA4C Gene
- MGI Knock Outs for SEMA4C:
-
- Sema4c Sema4c<tm1Matl>
Animal Model Products
-
Taconic Biosciences Mouse Models for SEMA4C
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SEMA4C - Select products 50% OFF >
- * SEMA4C CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SEMA4C
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEMA4C
-
Santa Cruz Biotechnology (SCBT) CRISPR for SEMA4C
miRNA for SEMA4C Gene
- miRTarBase miRNAs that target SEMA4C
-
- mmu-miR-181a-5p (MIRT014223)
- hsa-miR-19b-3p (MIRT031208)
- hsa-miR-193b-3p (MIRT041553)
- hsa-miR-16-5p (MIRT051307)
- hsa-miR-4633-3p (MIRT377246)
- hsa-miR-6500-5p (MIRT377252)
- hsa-miR-6514-3p (MIRT501212)
- hsa-miR-548aw (MIRT501214)
- hsa-miR-670-5p (MIRT501215)
- hsa-miR-550a-5p (MIRT501216)
- hsa-miR-550a-3-5p (MIRT501217)
- hsa-miR-1271-3p (MIRT501218)
- hsa-miR-6811-3p (MIRT501219)
- hsa-miR-1468-3p (MIRT501220)
- hsa-miR-548x-5p (MIRT501221)
- hsa-miR-548g-5p (MIRT501222)
- hsa-miR-548f-5p (MIRT501223)
- hsa-miR-548aj-5p (MIRT501224)
- hsa-miR-202-3p (MIRT501225)
- hsa-miR-548q (MIRT501226)
- hsa-miR-7162-3p (MIRT501227)
- hsa-miR-1914-5p (MIRT501228)
- hsa-miR-544b (MIRT501229)
- hsa-miR-4732-3p (MIRT501230)
- hsa-miR-345-3p (MIRT501231)
- hsa-miR-6834-3p (MIRT501232)
- hsa-miR-708-5p (MIRT501233)
- hsa-miR-3139 (MIRT501234)
- hsa-miR-28-5p (MIRT501235)
- hsa-miR-548n (MIRT501236)
- hsa-miR-4319 (MIRT501237)
- hsa-miR-125a-5p (MIRT501238)
- hsa-miR-125b-5p (MIRT501239)
- hsa-miR-4458 (MIRT501240)
- hsa-let-7e-5p (MIRT501241)
- hsa-let-7b-5p (MIRT501242)
- hsa-let-7a-5p (MIRT501243)
- hsa-let-7g-5p (MIRT501244)
- hsa-let-7i-5p (MIRT501245)
- hsa-let-7f-5p (MIRT501246)
- hsa-let-7d-5p (MIRT501247)
- hsa-let-7c-5p (MIRT501248)
- hsa-miR-4500 (MIRT501249)
- hsa-miR-98-5p (MIRT501250)
- hsa-miR-138-5p (MIRT501251)
- hsa-miR-214-5p (MIRT501252)
- hsa-miR-19a-3p (MIRT501253)
- hsa-miR-3941 (MIRT614775)
- hsa-miR-4643 (MIRT614776)
- hsa-miR-4789-3p (MIRT614777)
- hsa-miR-603 (MIRT614778)
- hsa-miR-362-3p (MIRT614779)
- hsa-miR-329-3p (MIRT614780)
- hsa-miR-8485 (MIRT614781)
- hsa-miR-8064 (MIRT666453)
- hsa-miR-25-3p (MIRT735454)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SEMA4C
- Browse OriGene Inhibitory RNA Products For SEMA4C
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEMA4C
Clone Products
- Applied Biological Materials (abm): Clones for SEMA4C - Select products 50% OFF >
- * SEMA4C as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SEMA4C
- Addgene plasmids for SEMA4C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEMA4C
Cell Line Products
-
Horizon Cell Lines for SEMA4C
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SEMA4C Gene
Localization for SEMA4C Gene
Subcellular locations from UniProtKB/Swiss-Prot for SEMA4C Gene
- Cell junction, synapse, postsynaptic density membrane. Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0005887 | integral component of plasma membrane | IBA | 21873635 |
| GO:0014069 | postsynaptic density | IEA,ISS | -- |
| GO:0016020 | membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SEMA4C Gene
Pathways & Interactions for SEMA4C Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Axon guidance | ||
Pathways by source for SEMA4C Gene
1 KEGG pathway for SEMA4C Gene
Interacting Proteins for SEMA4C Gene
Selected Interacting proteins:
Q9C0C4-SEM4C_HUMAN
ENSP00000306844
for SEMA4C Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SEMA4C
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001755 | neural crest cell migration | IBA | 21873635 |
| GO:0001843 | neural tube closure | IEA,ISS | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0007399 | nervous system development | IEA | -- |
| GO:0007411 | axon guidance | IBA | 21873635 |
No data available for SIGNOR curated interactions for SEMA4C Gene
Transcripts for SEMA4C Gene
mRNA/cDNA for SEMA4C Gene
- 1 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000305476 3652 nts (view in UCSC)
- ENST00000442264 817 nts (view in UCSC)
- ENST00000449330 839 nts (view in UCSC)
- ENST00000467747 3371 nts (view in UCSC)
- ENST00000474420 2625 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SEMA4C - Select products 50% OFF >
- * SEMA4C CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SEMA4C
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEMA4C
-
Santa Cruz Biotechnology (SCBT) CRISPR for SEMA4C
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SEMA4C
- Browse OriGene Inhibitory RNA Products For SEMA4C
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEMA4C
Clone Products
- Applied Biological Materials (abm): Clones for SEMA4C - Select products 50% OFF >
- * SEMA4C as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SEMA4C
- Addgene plasmids for SEMA4C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEMA4C
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | · | 17c | ^ | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - |
Relevant External Links for SEMA4C Gene
- GeneLoc Exon Structure for
- SEMA4C
Expression for SEMA4C Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Tube (Nervous System)
This gene is overexpressed in Fetal Brain (23.6), Heart (17.9), Spleen (7.3), and Placenta (6.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SEMA4C Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SEMA4C
SOURCE GeneReport for Unigene cluster for SEMA4C Gene:
Hs.516220Evidence on tissue expression from TISSUES for SEMA4C Gene
- Nervous system(4.8)
- Muscle(4.5)
- Liver(4.4)
- Eye(2.9)
- Heart(2.8)
- Skin(2.6)
- Spleen(2.6)
- Lymph node(2.5)
- Blood(2.5)
- Kidney(2.4)
- Lung(2.3)
- Intestine(2.1)
Primer Products
-
OriGene qPCR primer pairs for SEMA4C
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SEMA4C Gene
Orthologs for SEMA4C Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SEMA4C 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SEMA4C 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SEMA4C 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Sema4c 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | SEMA4C 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Sema4c 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SEMA4C 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | SEMA4C 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | sema4c 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | sc:d411 30 |
|
||
| SEMA4C 31 |
|
OneToOne | |||
| sema4e 30 |
|
- Species where no ortholog for SEMA4C was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for SEMA4C Gene
- ENSEMBL:
- Gene Tree for SEMA4C (if available)
- TreeFam:
- Gene Tree for SEMA4C (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SEMA4C: view image
Paralogs for SEMA4C Gene
Paralogs for SEMA4C Gene
(18) SIMAP similar genes for SEMA4C Gene using alignment to 5 proteins:
- SEM4C_HUMAN
- C9J4M7_HUMAN
- C9JV89_HUMAN
- Q53RE7_HUMAN
- Q6P5A5_HUMAN
Variants for SEMA4C Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv607e201 | CNV | deletion | 23290073 |
| esv3425717 | CNV | duplication | 20981092 |
| esv5003 | OTHER | complex | 18987735 |
| nsv1135873 | CNV | deletion | 24896259 |
| nsv526313 | CNV | loss | 19592680 |
Residual Variation Intolerance Score:
46.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.98;
68.23% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SEMA4C Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SEMA4C
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SEMA4C Gene
Disorders for SEMA4C Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cri-du-chat syndrome |
|
|
| kallmann syndrome |
|
|
Search SEMA4C in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SEMA4C
No data available for UniProtKB/Swiss-Prot and Genatlas for SEMA4C Gene
Publications for SEMA4C Gene
- Sema4C participates in myogenic differentiation in vivo and in vitro through the p38 MAPK pathway. (PMID: 17498836) Wu H … Fan M (European journal of cell biology 2007) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 3 4
- Identification of a member of mouse semaphorin family. (PMID: 7656991) Inagaki S … Iwahashi Y (FEBS letters 1995) 2 3
ExternalLinks
Products for SEMA4C Gene
- View all 13 R&D Systems SEMA4C (Semaphorin 4C) Products
- View all R&D Systems SEMA4C (Semaphorin 4C) Proteins and Enzymes
- View all 11 R&D Systems SEMA4C (Semaphorin 4C) Primary Antibodies
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- Learn more about R&D Systems custom SEMA4C antibody, protein, and immunoassay development services
- Custom Antibody ServicesOriGene Antibodies for SEMA4C
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SEMA4C
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- Origene shrna, sirna, and RNAi products in human, mouse, rat for SEMA4C
- Browse OriGene Inhibitory RNA Products For SEMA4C
- OriGene qPCR primer pairs for SEMA4C
- OriGene CRISPR knockouts for SEMA4C
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- Browse OriGene miRNA Products For SEMA4C
- Sino Biological Human cDNA Clone for SEMA4C
- Browse Sino Biological Recombinant Proteins
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- Browse Sino Biological Antibodies
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- Browse cDNA Clones
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SEMA4C
- Novus Biologicals proteins and lysates for SEMA4C
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Taconic Biosciences Mouse Models for SEMA4C
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for SEMA4C (AFLGC-SEMA4C)
- VectorBuilder Custom and pre-made DNA vectors for SEMA4C (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SEMA4C (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SEMA4C (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SEMA4C CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SEMA4C
- Addgene plasmids for SEMA4C
- antibodies-online: Show 10 available SEMA4C Antibodies ranked by validation data
- Compare Top SEMA4C Antibodies
- Recommended
- 34 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 5 IHC Antibodies (anti-human)
- 2 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-mouse)
- 9 WB Antibodies (anti-mouse)
- 8 FACS Antibodies (anti-mouse)
- 4 IHC Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 3 WB Antibodies (anti-rat)
- antibodies-online: Show 11 available SEMA4C Elisa Kits ranked by validation data
- Compare Top SEMA4C Elisa Kits
- Quality Products:
- antibodies-online: Show 8 available SEMA4C Proteins ranked by validation data
- Compare Top SEMA4C Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for SEMA4C
- Search Santa Cruz Biotechnology (SCBT) for SEMA4C siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SEMA4C
- Horizon Cell Lines for SEMA4C
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEMA4C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEMA4C
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SEMA4C
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEMA4C
- Signalway Proteins for SEMA4C
Sources for SEMA4C Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB