Aliases for SEMA3F Gene
External Ids for SEMA3F Gene
Previous GeneCards Identifiers for SEMA3F Gene
This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
GeneCards Summary for SEMA3F Gene
SEMA3F (Semaphorin 3F) is a Protein Coding gene. Diseases associated with SEMA3F include Wallerian Degeneration and Brachial Plexus Lesion. Among its related pathways are Axon guidance. Gene Ontology (GO) annotations related to this gene include receptor activity and chemorepellent activity. An important paralog of this gene is SEMA3C.
UniProtKB/Swiss-Prot for SEMA3F Gene
May play a role in cell motility and cell adhesion.