Aliases for SELENBP1 Gene
External Ids for SELENBP1 Gene
Previous GeneCards Identifiers for SELENBP1 Gene
This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
GeneCards Summary for SELENBP1 Gene
SELENBP1 (Selenium Binding Protein 1) is a Protein Coding gene. Diseases associated with SELENBP1 include Extraoral Halitosis Due To Methanethiol Oxidase Deficiency and Posteroinferior Myocardial Infarction. Among its related pathways are IL1 and megakaryocytes in obesity and Metabolism. Gene Ontology (GO) annotations related to this gene include selenium binding.
UniProtKB/Swiss-Prot Summary for SELENBP1 Gene
Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria (PubMed:29255262). Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity).