Aliases for SELENBP1 Gene
Aliases for SELENBP1 Gene
External Ids for SELENBP1 Gene
- HGNC: 10719
- Entrez Gene: 8991
- Ensembl: ENSG00000143416
- OMIM: 604188
- UniProtKB: Q13228
Previous GeneCards Identifiers for SELENBP1 Gene
- GC01M149178
- GC01M147084
- GC01M148111
- GC01M148554
- GC01M148555
- GC01M148149
- GC01M149603
- GC01M122714
Summaries for SELENBP1 Gene
-
This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
GeneCards Summary for SELENBP1 Gene
SELENBP1 (Selenium Binding Protein 1) is a Protein Coding gene. Diseases associated with SELENBP1 include Schizophrenia and Hypertension, Essential. Among its related pathways are IL1 and megakaryocytes in obesity and Selenium Metabolism and Selenoproteins. Gene Ontology (GO) annotations related to this gene include selenium binding.
UniProtKB/Swiss-Prot for SELENBP1 Gene
-
Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity).
Additional gene information for SELENBP1 Gene
- Monarch Initiative
- Search for SELENBP1 at DataMed
- Search for SELENBP1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SELENBP1 Gene
Genomics for SELENBP1 Gene
GeneHancer (GH) Regulatory Elements for SELENBP1 Gene
Promoters and enhancers for SELENBP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around SELENBP1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the SELENBP1 gene promoter:
Regulatory Element Products
Genomic Locations for SELENBP1 Gene
Genomic Locations for SELENBP1 Gene
- chr1:151,364,302-151,372,734
- (GRCh38/hg38)
- Size:
- 8,433 bases
- Orientation:
- Minus strand
- chr1:151,336,778-151,345,209
- (GRCh37/hg19)
Genomic View for SELENBP1 Gene
Genes around SELENBP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q21.3 by Ensembl
- 1q21.3 by Entrez Gene
- 1q21.3 by HGNC
SELENBP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SELENBP1 Gene
Proteins for SELENBP1 Gene
-
Protein details for SELENBP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q13228-SBP1_HUMAN
- Recommended name:
- Selenium-binding protein 1
- Protein Accession:
- Q13228
- A6NML9
- A6PVW9
- B2RDR3
- B4DKP6
- B4E1F3
- Q49AQ8
- Q96GX7
Protein attributes for SELENBP1 Gene
- Size:
- 472 amino acids
- Molecular mass:
- 52391 Da
- Quaternary structure:
-
- Interacts with USP33.
Protein Expression for SELENBP1 Gene
Post-translational modifications for SELENBP1 Gene
- Phosphorylated.
- The N-terminus is blocked.
Other Protein References for SELENBP1 Gene
Antibody Products
- Novus Biologicals Antibodies for SELENBP1
-
Abcam antibodies for SELENBP1
-
Cloud-Clone Corp. Antibodies for SELENBP1
- Invitrogen Antibodies for SELENBP1
- Search GeneTex for Antibodies for SELENBP1
-
Santa Cruz Biotechnology (SCBT) Antibodies for SELENBP1
Protein Products
-
OriGene Purified Proteins for SELENBP1
- Search Origene for MassSpec and Protein Over-expression Lysates for SELENBP1
- Origene Custom Protein Services for SELENBP1
-
Cloud-Clone Corp. Proteins for SELENBP1
- Search GeneTex for Proteins for SELENBP1
-
Abcam proteins for SELENBP1
Assay Products
-
Cloud-Clone Corp. Assay Kits for SELENBP1
No data available for DME Specific Peptides for SELENBP1 Gene
Domains & Families for SELENBP1 Gene
Gene Families for SELENBP1 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for SELENBP1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for SELENBP1 Gene
- GenScript: Design optimal peptide antigens:
-
- Selenium binding protein 1 (A6PVW8_HUMAN)
- Selenium binding protein 1 (A6PVX0_HUMAN)
- Selenium binding protein 1 (A6PVX2_HUMAN)
- cDNA FLJ61035, highly similar to Selenium-binding protein 1 (B4E1F3_HUMAN)
- cDNA FLJ13813 fis, clone THYRO1000358, moderately similar to SELENIUM-BINDING LIVER PROTEIN (Q9H8A8_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q13228- Family:
-
- Belongs to the selenium-binding protein family.
Function for SELENBP1 Gene
Molecular function for SELENBP1 Gene
- GENATLAS Biochemistry:
- selenium binding protein,56kDa,expressed in heart muscle and other tissues
- UniProtKB/Swiss-Prot Function:
- Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity).
- UniProtKB/Swiss-Prot Induction:
- Down-regulated by androgen in prostate cancer cells.
Phenotypes From GWAS Catalog for SELENBP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0008430 | selenium binding | IEA | -- |
Phenotypes for SELENBP1 Gene
- GenomeRNAi human phenotypes for SELENBP1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SELENBP1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SELENBP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SELENBP1 gene
- Search ViGene Biosciences for SELENBP1
CRISPR Products
-
OriGene CRISPR knockouts for SELENBP1
- genomics-online: gRNA clones - Search results for available SELENBP1 gene related products
- Applied Biological Materials CRISPR for SELENBP1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SELENBP1
- GenScript: Design CRISPR guide RNA sequences for SELENBP1
miRNA for SELENBP1 Gene
- miRTarBase miRNAs that target SELENBP1
miRNA Products
- Search ViGene Biosciences for SELENBP1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SELENBP1
- Browse OriGene Inhibitory RNA Products For SELENBP1
- genomics-online: shRNA clones - Search results for available SELENBP1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SELENBP1 gene
Clone Products
- Sino Biological Human cDNA Clone for SELENBP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SELENBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SELENBP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available SELENBP1 gene related products
- orf clones - Search results for available SELENBP1 gene related products
- Applied Biological Materials Clones for SELENBP1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for SELENBP1
-
ViGene Biosciences adenoviral particle packaged cDNA for SELENBP1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SELENBP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SELENBP1 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SELENBP1 Gene
Localization for SELENBP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SELENBP1 Gene
- Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane (By similarity). May associate with the membrane of autophagosomes (By similarity). {ECO:0000250 UniProtKB:Q8VIF7}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 4 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Nucleoli (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001650 | fibrillar center | IDA | -- |
| GO:0005615 | extracellular space | IDA,HDA | 16502470 |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005730 | nucleolus | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for SELENBP1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | IL1 and megakaryocytes in obesity | ||
| 2 | Selenium Metabolism and Selenoproteins | ||
Pathways by source for SELENBP1 Gene
2 BioSystems pathways for SELENBP1 Gene
Interacting Proteins for SELENBP1 Gene
Selected Interacting proteins:
Q13228-SBP1_HUMAN
ENSP00000357861
for SELENBP1 Gene via
IID
UniProtKB
STRING
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0015031 | protein transport | IEA | -- |
No data available for SIGNOR curated interactions for SELENBP1 Gene
Drugs & Compounds for SELENBP1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Selenium | Approved, Investigational, Vet_approved | Pharma | 193 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for SELENBP1 Gene
mRNA/cDNA for SELENBP1 Gene
- (4) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (450) Selected AceView cDNA sequences:
- (19) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SELENBP1 Gene
- Selenium binding protein 1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for SELENBP1
- genomics-online: gRNA clones - Search results for available SELENBP1 gene related products
- Applied Biological Materials CRISPR for SELENBP1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SELENBP1
- GenScript: Design CRISPR guide RNA sequences for SELENBP1
miRNA Products
- Search ViGene Biosciences for SELENBP1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SELENBP1
- Browse OriGene Inhibitory RNA Products For SELENBP1
- genomics-online: shRNA clones - Search results for available SELENBP1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SELENBP1 gene
Clone Products
- Sino Biological Human cDNA Clone for SELENBP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SELENBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SELENBP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available SELENBP1 gene related products
- orf clones - Search results for available SELENBP1 gene related products
- Applied Biological Materials Clones for SELENBP1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP21: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP22: | - |
| ExUns: | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||
| SP2: | |||||||||
| SP3: | |||||||||
| SP4: | |||||||||
| SP5: | |||||||||
| SP6: | |||||||||
| SP7: | |||||||||
| SP8: | |||||||||
| SP9: | |||||||||
| SP10: | |||||||||
| SP11: | |||||||||
| SP12: | |||||||||
| SP13: | |||||||||
| SP14: | |||||||||
| SP15: | |||||||||
| SP16: | |||||||||
| SP17: | |||||||||
| SP18: | |||||||||
| SP19: | |||||||||
| SP20: | |||||||||
| SP21: | |||||||||
| SP22: |
Expression for SELENBP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
-
Blood (Hematopoietic System)
- Erythroblasts Hematopoietic Bone Marrow
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
- Colon (Gastrointestinal Tract)
- Intestine (Gastrointestinal Tract)
- Bone (Muscoskeletal System)
- Ovary (Reproductive System)
- Adipose (Muscoskeletal System)
-
Prostate (Endocrine System)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Kidney (Urinary System)
-
Stomach (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for SELENBP1 Gene
This gene is overexpressed in Colon - Transverse (x12.9).
This gene is overexpressed in Liver, secretome (8.0) and Nasal epithelium (6.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SELENBP1 Gene
NURSA nuclear receptor signaling pathways regulating expression of SELENBP1 Gene:
SELENBP1SOURCE GeneReport for Unigene cluster for SELENBP1 Gene:
Hs.632460mRNA Expression by UniProt/SwissProt for SELENBP1 Gene:
Q13228-SBP1_HUMAN
Tissue specificity:
Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.
Evidence on tissue expression from TISSUES for SELENBP1 Gene
- Intestine(4.9)
- Nervous system(4.9)
- Liver(4.7)
- Lung(4.7)
- Heart(4.6)
- Blood(3.6)
- Kidney(2.7)
- Muscle(2.1)
- Thyroid gland(2)
Primer Products
-
OriGene qPCR primer pairs for SELENBP1
-
OriGene qPCR primer pairs and template standards for SELENBP1
- genomics-online: primer clones - Search results for available SELENBP1 gene related products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for SELENBP1 Gene
Orthologs for SELENBP1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SELENBP1 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | SELENBP1 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | SELENBP1 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Selenbp1 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Selenbp2 16 34 |
|
||
| Selenbp1 33 34 |
|
||||
| oppossum (Monodelphis domestica) |
Mammalia | SELENBP1 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SELENBP1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | -- 34 |
|
OneToMany | |
| SELENBP1 33 34 34 |
|
||||
| -- 34 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | selenbp1 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.4889 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | selenbp1 33 34 |
|
||
| zgc65844 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.3726 33 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP011531 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG7966 35 33 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | CELE_Y37A1B.5 33 |
|
||
| Y37A1B.5 35 34 |
|
||||
| R11G10.2 35 34 |
|
||||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | SBP3 33 |
|
||
| soybean (Glycine max) |
eudicotyledons | Gma.8462 33 |
|
||
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.1445 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os01g0916400 33 |
|
||
| Os.8353 33 |
|
||||
| barley (Hordeum vulgare) |
Liliopsida | Hv.763 33 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.22952 33 |
|
||
| corn (Zea mays) |
Liliopsida | Zm.7068 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.2769 33 |
|
- Species where no ortholog for SELENBP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Paralogs for SELENBP1 Gene
(1) SIMAP similar genes for SELENBP1 Gene using alignment to 9 proteins:
No data available for Paralogs for SELENBP1 Gene
Variants for SELENBP1 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000890101 | -- | 151,370,871(-) | G/T | intron_variant | |
| rs1000965504 | -- | 151,370,041(-) | G/A | intron_variant | |
| rs1001789655 | -- | 151,366,011(-) | G/A/T | genic_downstream_transcript_variant, intron_variant | |
| rs1001937682 | -- | 151,371,760(-) | C/A | intron_variant | |
| rs1001991988 | -- | 151,371,275(-) | G/A | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv8380 | CNV | gain | 18304495 |
| nsv831581 | CNV | loss | 17160897 |
| nsv824575 | CNV | gain | 20364138 |
| nsv818467 | CNV | gain | 17921354 |
| nsv522840 | CNV | gain | 19592680 |
| nsv470737 | CNV | gain | 18288195 |
| nsv441714 | CNV | gain | 18776908 |
| nsv438026 | CNV | loss | 16468122 |
| nsv1161560 | CNV | duplication | 26073780 |
| esv3894200 | CNV | gain | 25118596 |
| esv3587526 | CNV | loss | 21293372 |
| esv3587525 | CNV | gain | 21293372 |
| esv34461 | CNV | gain | 17911159 |
| esv2758969 | CNV | gain | 17122850 |
| dgv564n54 | CNV | gain | 21841781 |
| dgv53e214 | CNV | gain | 21293372 |
| dgv36n27 | CNV | gain | 19166990 |
Residual Variation Intolerance Score:
67.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.28;
53.06% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SELENBP1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SELENBP1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SELENBP1 Gene
Disorders for SELENBP1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| schizophrenia |
|
|
| hypertension, essential |
|
|
Search SELENBP1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SELENBP1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for SELENBP1 Gene
Publications for SELENBP1 Gene
- Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner. (PMID: 19118533) Jeong JY … Sytkowski AJ (Biochemical and biophysical research communications 2009) 3 4 22 58
- Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival. (PMID: 16645984) Kim H … Kim H (Proteomics 2006) 3 4 22 58
- Selenium binding protein 1 in ovarian cancer. (PMID: 16380993) Huang KC … Ng SW (International journal of cancer 2006) 3 4 22 58
- Isolation, characterization, and chromosomal mapping of a novel cDNA clone encoding human selenium binding protein. (PMID: 9027582) Chang PW … Fung KP (Journal of cellular biochemistry 1997) 2 3 4 58
- Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". (PMID: 20628624) Johnatty SE … Australian Cancer Study (Ovarian Cancer) (PLoS genetics 2010) 3 44 58
Products for SELENBP1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for SELENBP1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SELENBP1
- Search Origene for MassSpec and Protein Over-expression Lysates for SELENBP1
- Origene Custom Protein Services for SELENBP1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SELENBP1
- Browse OriGene Inhibitory RNA Products For SELENBP1
- OriGene qPCR primer pairs and template standards for SELENBP1
- OriGene qPCR primer pairs for SELENBP1
- OriGene CRISPR knockouts for SELENBP1
- OriGene ORF clones in human for SELENBP1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SELENBP1
- GenScript: Next-day shipping of latest version cDNA ORF clones for SELENBP1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for SELENBP1
- GenScript Custom Assay Services for SELENBP1
- GenScript Custom overexpressing Cell Line Services for SELENBP1
- GenScript: Design CRISPR guide RNA sequences for SELENBP1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for SELENBP1
- Sino Biological Human cDNA Clone for SELENBP1
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for SELENBP1
- Novus Biologicals lysates and proteins for SELENBP1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SELENBP1
- Abcam proteins for SELENBP1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Cloud-Clone Corp. Antibodies for SELENBP1
- Cloud-Clone Corp. Proteins for SELENBP1
- Cloud-Clone Corp. Assay Kits for SELENBP1
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for SELENBP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for SELENBP1
- VectorBuilder custom plasmid, inducible vectors for SELENBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SELENBP1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 99 available SELENBP1 Antibodies ranked by validation data
- Compare Top SELENBP1 Antibodies
- antibodies-online: Search results for 14 available SELENBP1 Elisa Kits ranked by validation data
- Compare Top SELENBP1 Elisa Kits
- antibodies-online: Search results for 12 available SELENBP1 Proteins ranked by validation data
- Compare Top SELENBP1 Proteins
- Search GeneTex for Antibodies for SELENBP1
- Search GeneTex for Proteins for SELENBP1
- ViGene Biosciences adenoviral particle packaged cDNA for SELENBP1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for SELENBP1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for SELENBP1 gene
- Search ViGene Biosciences for SELENBP1
- Santa Cruz Biotechnology (SCBT) Antibodies for SELENBP1
- Search Santa Cruz Biotechnology (SCBT) for SELENBP1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SELENBP1
- Horizon Cell Lines for SELENBP1
- genomics-online: cdna clones - Search results for available SELENBP1 gene related products
- orf clones - Search results for available SELENBP1 gene related products
- genomics-online: gRNA clones - Search results for available SELENBP1 gene related products
- genomics-online: primer clones - Search results for available SELENBP1 gene related products
- genomics-online: shRNA clones - Search results for available SELENBP1 gene related products
Sources for SELENBP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew