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SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).[supplied by OMIM, Jun 2009] See more...
Aliases for SEC16B Gene
Aliases for SEC16B Gene
External Ids for SEC16B Gene
- HGNC: 30301
- Entrez Gene: 89866
- Ensembl: ENSG00000120341
- OMIM: 612855
- UniProtKB: Q96JE7
Previous HGNC Symbols for SEC16B Gene
- LZTR2
Previous GeneCards Identifiers for SEC16B Gene
- GC01M176166
- GC01M177896
- GC01M149125
Summaries for SEC16B Gene
-
SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).[supplied by OMIM, Jun 2009]
GeneCards Summary for SEC16B Gene
SEC16B (SEC16 Homolog B, Endoplasmic Reticulum Export Factor) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism of proteins. An important paralog of this gene is SEC16A.
UniProtKB/Swiss-Prot Summary for SEC16B Gene
-
Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:17192411, PubMed:21768384, PubMed:22355596). Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes (PubMed:21768384).
Additional gene information for SEC16B Gene
- HGNC(30301)
- Entrez Gene(89866)
- Ensembl(ENSG00000120341)
- OMIM(612855)
- UniProtKB(Q96JE7)
- Open Targets Platform(ENSG00000120341)
- Monarch Initiative
- Search for SEC16B at DataMed
- Search for SEC16B at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SEC16B Gene
Genomics for SEC16B Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SEC16B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SEC16B on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SEC16B
- Top Transcription factor binding sites by QIAGEN in the SEC16B gene promoter:
-
- Brachyury
- CREB
- deltaCREB
- FOXI1
- HFH-3
- MRF-2
- Pbx1a
- POU3F1
- STAT5B
- TBP
Genomic Locations for SEC16B Gene
Genomic Locations for SEC16B Gene
- chr1:177,923,956-177,984,303
- (GRCh38/hg38)
- Size:
- 60,348 bases
- Orientation:
- Minus strand
- chr1:177,893,091-177,953,438
- (GRCh37/hg19)
- Size:
- 60,348 bases
- Orientation:
- Minus strand
Genomic View for SEC16B Gene
Genes around SEC16B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q25.2 by HGNC
- 1q25.2 by Entrez Gene
- 1q25.2 by Ensembl
SEC16B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SEC16B Gene
Proteins for SEC16B Gene
-
Protein details for SEC16B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96JE7-SC16B_HUMAN
- Recommended name:
- Protein transport protein Sec16B
- Protein Accession:
- Q96JE7
- A3EYF1
- Q5HYF6
- Q8N7D6
- Q96GX6
Protein attributes for SEC16B Gene
- Size:
- 1060 amino acids
- Molecular mass:
- 116604 Da
- Quaternary structure:
-
- SEC16A and SEC16B are each present in multiple copies in a heteromeric complex (PubMed:17192411, PubMed:22355596). Interacts with TFG (PubMed:21478858). Interacts with SEC13 (PubMed:22355596).
Protein Expression for SEC16B Gene
Post-translational modifications for SEC16B Gene
Other Protein References for SEC16B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-SEC16B monoclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for SEC16B
- Novus Biologicals Antibodies for SEC16B
-
Abcam antibodies for SEC16B
- Invitrogen Antibodies for SEC16B (AFLGC-SEC16B)
-
Boster Bio Antibodies for SEC16B
-
Custom Antibody ServicesProSci Antibodies for SEC16B
Protein Products
-
OriGene Purified Proteins for SEC16B
- Search Origene for MassSpec and Protein Over-expression Lysates for SEC16B
- Origene Custom Protein Services for SEC16B
- antibodies-online: Show 3 available SEC16B Proteins ranked by validation data
- Compare Top SEC16B Proteins
-
Quality Products:
-
Abcam proteins for SEC16B
No data available for DME Specific Peptides for SEC16B Gene
Domains & Families for SEC16B Gene
Gene Families for SEC16B Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for SEC16B Gene
- InterPro:
- Blocks:
-
- Phosphopantetheine attachment site
- ProtoNet:
Suggested Antigen Peptide Sequences for SEC16B Gene
- GenScript: Design optimal peptide antigens:
-
- SEC16 homolog B (S. cerevisiae) (B1AM07_HUMAN)
- SEC16 homolog B (S. cerevisiae) (B1AM08_HUMAN)
- KIAA1928 protein (Q96PW0_HUMAN)
- SEC16 homolog B (SC16B_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96JE7- Family:
-
- Belongs to the SEC16 family.
Function for SEC16B Gene
Molecular function for SEC16B Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:17192411, PubMed:21768384, PubMed:22355596). Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes (PubMed:21768384).
Phenotypes From GWAS Catalog for SEC16B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 21478858 |
Phenotypes for SEC16B Gene
- MGI mutant phenotypes for SEC16B:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SEC16B:
Animal Models for SEC16B Gene
- MGI Knock Outs for SEC16B:
-
- Sec16b Sec16b<tm1a(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SEC16B - Select products 50% OFF >
- * SEC16B CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SEC16B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEC16B
-
Santa Cruz Biotechnology (SCBT) CRISPR for SEC16B
miRNA for SEC16B Gene
- miRTarBase miRNAs that target SEC16B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SEC16B
- Browse OriGene Inhibitory RNA Products For SEC16B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEC16B
Clone Products
- Applied Biological Materials (abm): Clones for SEC16B - Select products 50% OFF >
- * SEC16B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SEC16B
- Addgene plasmids for SEC16B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEC16B
Cell Line Products
-
Horizon Cell Lines for SEC16B
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SEC16B Gene
Localization for SEC16B Gene
Subcellular locations from UniProtKB/Swiss-Prot for SEC16B Gene
- Endoplasmic reticulum membrane. Peripheral membrane protein. Golgi apparatus membrane. Peripheral membrane protein. Note=Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). {ECO:0000269 PubMed:17192411, ECO:0000269 PubMed:21478858, ECO:0000269 PubMed:21768384, ECO:0000269 PubMed:22355596}.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| cytosol | 4 |
| nucleus | 3 |
| golgi apparatus | 3 |
| peroxisome | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endosome | 1 |
- Actin filaments (2)
- Endoplasmic reticulum (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | -- |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for SEC16B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transport to the Golgi and subsequent modification | ||
| 2 | Vesicle-mediated transport | ||
| 3 | Metabolism of proteins | ||
Pathways by source for SEC16B Gene
8 Reactome pathways for SEC16B Gene
Interacting Proteins for SEC16B Gene
Selected Interacting proteins:
Q96JE7-SC16B_HUMAN
ENSP00000308339
for SEC16B Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SEC16B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006888 | ER to Golgi vesicle-mediated transport | TAS | 22355596 |
| GO:0007029 | endoplasmic reticulum organization | IBA,IDA | 21768384 |
| GO:0007030 | Golgi organization | IBA | 21873635 |
| GO:0007031 | peroxisome organization | IEA,IDA | 21768384 |
| GO:0010628 | positive regulation of gene expression | IMP | 21768384 |
Transcripts for SEC16B Gene
mRNA/cDNA for SEC16B Gene
- 3 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000308284 3985 nts (view in UCSC)
- ENST00000327037 1807 nts (view in UCSC)
- ENST00000441371 811 nts (view in UCSC)
- ENST00000464631 2948 nts (view in UCSC)
- ENST00000495165 2643 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SEC16B - Select products 50% OFF >
- * SEC16B CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SEC16B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEC16B
-
Santa Cruz Biotechnology (SCBT) CRISPR for SEC16B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SEC16B
- Browse OriGene Inhibitory RNA Products For SEC16B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEC16B
Clone Products
- Applied Biological Materials (abm): Clones for SEC16B - Select products 50% OFF >
- * SEC16B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SEC16B
- Addgene plasmids for SEC16B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEC16B
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP2: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: |
| ExUns: | 22a | · | 22b | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27a | · | 27b | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39a | · | 39b | · | 39c | · | 39d | ^ | 40 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP12: |
Relevant External Links for SEC16B Gene
- GeneLoc Exon Structure for
- SEC16B
Expression for SEC16B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Adipose (Muscoskeletal System)
- Mesenchymal Stem Cells Subcutaneous White Adipose
-
Mesenchymal Stem Cells
- Mesenchymal Stem Cells Subcutaneous White Adipose
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Liver (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for SEC16B Gene
This gene is overexpressed in Liver (x14.1).
This gene is overexpressed in Liver (42.3), Fetal Liver (16.4), and Pancreas (10.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SEC16B Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SEC16B
SOURCE GeneReport for Unigene cluster for SEC16B Gene:
Hs.149540mRNA Expression by UniProt/SwissProt for SEC16B Gene:
Q96JE7-SC16B_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for SEC16B Gene
- Liver(4.5)
- Eye(4.3)
- Skin(2.2)
Primer Products
-
OriGene qPCR primer pairs for SEC16B
-
OriGene qPCR primer pairs and template standards for SEC16B
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for SEC16B Gene
Orthologs for SEC16B Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SEC16B 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | SEC16B 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SEC16B 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Sec16b 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Sec16b 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | SEC16B 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SEC16B 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | SEC16B 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SEC16B 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | sec16b 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | SEC16B 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | Sec16 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | sec-16 31 |
|
ManyToMany | |
| F13B9.1 31 |
|
ManyToMany |
- Species where no ortholog for SEC16B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for SEC16B Gene
- ENSEMBL:
- Gene Tree for SEC16B (if available)
- TreeFam:
- Gene Tree for SEC16B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SEC16B: view image
Paralogs for SEC16B Gene
Variants for SEC16B Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SEC16B Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 720900 | Benign: not provided | 177,933,233(-) | G/A | MISSENSE_VARIANT | |
| 732165 | Likely Benign: not provided | 177,936,319(-) | T/G | MISSENSE_VARIANT | |
| 732634 | Benign: not provided | 177,967,930(-) | C/T | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR_VARIANT | |
| 746400 | Likely Benign: not provided | 177,960,356(-) | T/C | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT,INTRON_VARIANT | |
| 773416 | Likely Benign: not provided | 177,947,920(-) | C/T | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2663986 | CNV | deletion | 23128226 |
| esv2719829 | CNV | deletion | 23290073 |
| nsv1010839 | CNV | loss | 25217958 |
| nsv548252 | CNV | gain | 21841781 |
| nsv548253 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
99.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
13.53;
95.56% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SEC16B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SEC16B
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SEC16B Gene
Disorders for SEC16B Gene
Additional Disease Information for SEC16B
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for SEC16B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SEC16B Gene
Publications for SEC16B Gene
- Molecular cloning and sequencing of the cDNA coding for a novel regucalcin gene promoter region-related protein in rat, mouse and human liver. (PMID: 11605020) Misawa H … Yamaguchi M (International journal of molecular medicine 2001) 2 3 4 23
- Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells. (PMID: 21768384) Yonekawa S … Tani K (Proceedings of the National Academy of Sciences of the United States of America 2011) 2 3 4
- Two mammalian Sec16 homologues have nonredundant functions in endoplasmic reticulum (ER) export and transitional ER organization. (PMID: 17192411) Bhattacharyya D … Glick BS (Molecular biology of the cell 2007) 2 3 4
- Characterization of human Sec16B: indications of specialized, non-redundant functions. (PMID: 22355596) Budnik A … Stephens DJ (Scientific reports 2011) 3 4
- TFG-1 function in protein secretion and oncogenesis. (PMID: 21478858) Witte K … Audhya A (Nature cell biology 2011) 3 4
ExternalLinks
Products for SEC16B Gene
- Custom Antibody ServicesOriGene Antibodies for SEC16B
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SEC16B
- Search Origene for MassSpec and Protein Over-expression Lysates for SEC16B
- Origene Custom Protein Services for SEC16B
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SEC16B
- Browse OriGene Inhibitory RNA Products For SEC16B
- OriGene qPCR primer pairs for SEC16B
- OriGene qPCR primer pairs and template standards for SEC16B
- OriGene CRISPR knockouts for SEC16B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SEC16B
- Sino Biological Human cDNA Clone for SEC16B
- Browse Sino Biological Recombinant Proteins
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- Browse Sino Biological Antibodies
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- High-throughput Antibody Production Service
- Protein Production Service
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- Novus Biologicals Antibodies for SEC16B
- Novus Biologicals proteins and lysates for SEC16B
- Browse Antibodies
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- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SEC16B
- Abcam proteins for SEC16B
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- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse ELISA Kits
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
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- Invitrogen Antibodies for SEC16B (AFLGC-SEC16B)
- VectorBuilder Custom and pre-made DNA vectors for SEC16B (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SEC16B (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for SEC16B (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for SEC16B CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for SEC16B
- Addgene plasmids for SEC16B
- antibodies-online: Show 4 available SEC16B Antibodies ranked by validation data
- Compare Top SEC16B Antibodies
- antibodies-online: Search results for available SEC16B related products ranked by validation data
- antibodies-online: Show 3 available SEC16B Proteins ranked by validation data
- Compare Top SEC16B Proteins
- Quality Products:
- Custom Antibody ServicesProSci Antibodies for SEC16B
- Search for SEC16B Proteins at ProSci
- Horizon Cell Lines for SEC16B
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SEC16B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SEC16B
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SEC16B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SEC16B
- Boster Bio Antibodies for SEC16B
- Browse Boster Bio ELISA Kits
Sources for SEC16B Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB