Aliases for SEC16B Gene
External Ids for SEC16B Gene
Previous HGNC Symbols for SEC16B Gene
Previous GeneCards Identifiers for SEC16B Gene
SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).[supplied by OMIM, Jun 2009]
GeneCards Summary for SEC16B Gene
SEC16B (SEC16 Homolog B, Endoplasmic Reticulum Export Factor) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Transport to the Golgi and subsequent modification. An important paralog of this gene is SEC16A.
UniProtKB/Swiss-Prot Summary for SEC16B Gene
Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:17192411, PubMed:21768384, PubMed:22355596). Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes (PubMed:21768384).