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SDR42E1 (Short Chain Dehydrogenase/Reductase Family 42E, Member 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and 3-beta-hydroxy-delta5-steroid dehydrogenase activity. An important paralog of this gene is SDR42E2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity | IEA | -- |
GO:0016491 | oxidoreductase activity | IEA | -- |
GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA,IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006694 | steroid biosynthetic process | IEA | -- |
GO:0055114 | oxidation-reduction process | IEA | -- |
ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||
SP2: | |||||||||||||||
SP3: | - | - |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SDR42E1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | SDR42E1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | SDR42E1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Sdr42e1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Sdr42e1 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | SDR42E1 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | SDR42E1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | SDR42E1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | SDR42E1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | sdr42e1 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.32536 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | sdr42e1 30 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | hsd-3 31 |
|
ManyToMany | |
hsd-2 31 |
|
ManyToMany | |||
hsd-1 31 |
|
ManyToMany | |||
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ERG26 31 |
|
OneToMany | |
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT2G33630 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os02g0715200 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.9296 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs16956174 | - |
p.Lys96Glu |
|||
rs3813012 | - |
p.Gly320Asp |
|||
rs6564956 | - |
p.Ser10Thr |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2660861 | CNV | deletion | 23128226 |
esv3639348 | CNV | loss | 21293372 |
No disorders were found for SDR42E1 Gene.