Aliases for SDC4 Gene
External Ids for SDC4 Gene
Previous GeneCards Identifiers for SDC4 Gene
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
GeneCards Summary for SDC4 Gene
SDC4 (Syndecan 4) is a Protein Coding gene. Diseases associated with SDC4 include Thyroid Cancer and Juvenile Astrocytoma. Among its related pathways are Chondroitin sulfate/dermatan sulfate metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include cytoskeletal protein binding and fibronectin binding. An important paralog of this gene is SDC3.
UniProtKB/Swiss-Prot for SDC4 Gene
Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).