Aliases for SDC4 Gene
External Ids for SDC4 Gene
Previous GeneCards Identifiers for SDC4 Gene
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
GeneCards Summary for SDC4 Gene
SDC4 (Syndecan 4) is a Protein Coding gene. Diseases associated with SDC4 include Thyroid Carcinoma and Type 2 Diabetes Mellitus. Among its related pathways are MET promotes cell motility and Proteoglycans in cancer. Gene Ontology (GO) annotations related to this gene include cytoskeletal protein binding and fibronectin binding. An important paralog of this gene is SDC2.
UniProtKB/Swiss-Prot Summary for SDC4 Gene
Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).