Aliases for SDC3 Gene
External Ids for SDC3 Gene
Previous GeneCards Identifiers for SDC3 Gene
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009]
GeneCards Summary for SDC3 Gene
SDC3 (Syndecan 3) is a Protein Coding gene. Diseases associated with SDC3 include Body Mass Index Quantitative Trait Locus 11 and Charcot-Marie-Tooth Disease, Dominant Intermediate C. Among its related pathways are Development Slit-Robo signaling and Glycosaminoglycan metabolism. Gene Ontology (GO) annotations related to this gene include cytoskeletal protein binding. An important paralog of this gene is SDC1.
UniProtKB/Swiss-Prot for SDC3 Gene
Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.